Probable peroxidase 26 precursor - Arabidopsis thaliana (Mouse-ear cress)

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O22862 (PER26_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 94. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Probable peroxidase 26
Short name=Atperox P26
EC=1.11.1.7

Alternative name(s):
ATP50

Gene names

Name:	PER26
Synonyms:	P26
Ordered Locus Names:	At2g43480
ORF Names:	T1O24.22

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Removal of H₂O₂, oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress Probable. The enzyme activity has to be proved.
Catalytic activity	2 phenolic donor + H₂O₂ = 2 phenoxyl radical of the donor + 2 H₂O.
Cofactor	Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. Binds 2 calcium ions per subunit By similarity.
Subcellular location	Secreted By similarity.
Miscellaneous	There are 73 peroxidase genes in A.thaliana.
Sequence similarities	Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
Caution	Lacks the distal histidine (here Ser-77), present in the active site, which is one of the conserved features of the classical plant (class III) peroxidase family.
Sequence caution	The sequence AAB64327.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Ligand	Calcium Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	response to oxidative stress Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	heme binding Inferred from electronic annotation. Source: InterPro peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

1 – 18

Potential

Chain

19 – 335

317

Probable peroxidase 26

PRO_0000023692

Sites

Active site

By similarity

Metal binding

Calcium 1 By similarity

Metal binding

Calcium 1; via carbonyl oxygen By similarity

Metal binding

Calcium 1; via carbonyl oxygen By similarity

Metal binding

Calcium 1 By similarity

Metal binding

Calcium 1 By similarity

Metal binding

198

Iron (heme axial ligand) By similarity

Metal binding

199

Calcium 2 By similarity

Metal binding

255

Calcium 2 By similarity

Metal binding

258

Calcium 2 By similarity

Binding site

168

Substrate; via carbonyl oxygen By similarity

Amino acid modifications

Glycosylation

216

N-linked (GlcNAc...) Potential

Glycosylation

259

N-linked (GlcNAc...) Potential

Glycosylation

273

N-linked (GlcNAc...) Potential

Disulfide bond

46 ↔ 122

By similarity

Disulfide bond

79 ↔ 84

By similarity

Disulfide bond

128 ↔ 331

By similarity

Disulfide bond

205 ↔ 237

By similarity

Experimental info

Sequence conflict

140

V → I in AAL84934. Ref.3

Sequence conflict

189

L → R in AAL84934. Ref.3

Sequence conflict

208

V → A in AAL84934. Ref.3

Sequence conflict

286

N → D in AAL84934. Ref.3

Sequences

Sequence

Length

Mass (Da)

Tools

O22862 [UniParc].

Last modified November 25, 2002. Version 2.
Checksum: CAF4B893D9C3CC24
Show »

FASTA

335

37,568

        10         20         30         40         50         60 
MVMIHIFLTV MVVGGVSLFP ETAEAIVMGP SMQKLTWHYY KVYNTCENAE NFVRHQVEIF 

        70         80         90        100        110        120 
YKNDKSIAPK LLRLLYSDCF VSGCDASVLL EGPNSEKMAP QNRGLGGFVL IDKIKIVLEQ 

       130        140        150        160        170        180 
RCPGVVSCAD ILNLATRDAV HLAGAPSYPV FTGRRDGLTS DKQTVDLPSP SISWDQAMSY 

       190        200        210        220        230        240 
FKSRGLNVLD MATLLGSHSM GRTHCSYVVD RLYNYNKTGK PSPTMNKYFL SEMAKQCPPR 

       250        260        270        280        290        300 
TRKGQTDPLV YLNPDSGSNH SFTSSFYSRI LSNKSVLEVD QQLLYNDDTK QISKEFSEGF 

       310        320        330 
EDFRKSFALS MSKMGAINVL TKTEGEIRKD CRHIN

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. Venter J.C. Nature 402:761-768(1999) [PubMed: 10617197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana." Tognolli M., Penel C., Greppin H., Simon P. Gene 288:129-138(2002) [PubMed: 12034502] [Abstract] Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC002335 Genomic DNA. Translation: AAB64327.1. Different initiation. CP002685 Genomic DNA. Translation: AEC10275.1. AY078928 mRNA. Translation: AAL84934.1.
IPI	IPI00520349.
RefSeq	NP_181876.2. NM_129909.2.
UniGene	At.36889.
3D structure databases
ProteinModelPortal	O22862.
SMR	O22862. Positions 34-335.
ModBase	Search...
Protein-protein interaction databases
STRING	O22862.
Protein family/group databases
PeroxiBase	119. AtPrx26.
Proteomic databases
PRIDE	O22862.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT2G43480.1; AT2G43480.1; AT2G43480.
GeneID	818949.
GenomeReviews	Gene locus AT2G43480 in contig CT485783_GR.
KEGG	ath:AT2G43480.
NMPDR	fig\|3702.1.peg.11504.
Organism-specific databases
GeneFarm	1853. 61.
TAIR	At2g43480.
Phylogenomic databases
GeneTree	EPGT00050000003673.
HOGENOM	HBG597790.
InParanoid	O22862.
OMA	CENAENF.
PhylomeDB	O22862.
ProtClustDB	CLSN2686312.
Gene expression databases
ArrayExpress	O22862.
Genevestigator	O22862.
GermOnline	AT2G43480. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR010255. Haem_peroxidase. IPR002016. Haem_peroxidase_pln/fun/bac. IPR000823. Peroxidase_pln. IPR019793. Peroxidases_heam-ligand_BS. [Graphical view]
KO	K00430.
Pfam	PF00141. peroxidase. 1 hit. [Graphical view]
PRINTS	PR00458. PEROXIDASE. PR00461. PLPEROXIDASE.
SUPFAM	SSF48113. Peroxidase_super. 1 hit.
PROSITE	PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. False negative. PS50873. PEROXIDASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PER26_ARATH

Accession

Primary (citable) accession number: O22862
Secondary accession number(s): Q8RY36

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 25, 2002
Last sequence update:	November 25, 2002
Last modified:	December 14, 2011
This is version 94 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Sites

Amino acid modifications

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents