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Protein

Calmodulin-like protein 5

Gene

CML5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Potential calcium sensor.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi74 – 851PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi110 – 1212PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi152 – 1633PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi190 – 2014PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

LigandCalcium, Metal-binding

Enzyme and pathway databases

ReactomeiR-ATH-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Calmodulin-like protein 5
Alternative name(s):
Protein MULTICOPY SUPPRESSORS OF SNF4 DEFICIENCY IN YEAST 3
Gene namesi
Name:CML5
Synonyms:MSS3
Ordered Locus Names:At2g43290
ORF Names:F14B2.33, T1O24.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G43290
TAIRilocus:2058198 AT2G43290

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003428881 – 215Calmodulin-like protein 5Add BLAST215

Proteomic databases

PaxDbiO22845

Expressioni

Inductioni

By touch and during darkness conditions.1 Publication

Gene expression databases

ExpressionAtlasiO22845 baseline and differential
GenevisibleiO22845 AT

Interactioni

Protein-protein interaction databases

BioGridi4268, 3 interactors
STRINGi3702.AT2G43290.1

Structurei

3D structure databases

ProteinModelPortaliO22845
SMRiO22845
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 96EF-hand 1PROSITE-ProRule annotationAdd BLAST36
Domaini97 – 132EF-hand 2PROSITE-ProRule annotationAdd BLAST36
Domaini139 – 174EF-hand 3PROSITE-ProRule annotationAdd BLAST36
Domaini177 – 212EF-hand 4PROSITE-ProRule annotationAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi50 – 55Poly-Ser6

Sequence similaritiesi

Belongs to the calmodulin family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
HOGENOMiHOG000233018
InParanoidiO22845
KOiK13448
OMAiIVDEHHN
OrthoDBiEOG09360QFU
PhylomeDBiO22845

Family and domain databases

CDDicd00051 EFh, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13499 EF-hand_7, 2 hits
SMARTiView protein in SMART
SM00054 EFh, 4 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 4 hits
PS50222 EF_HAND_2, 4 hits

Sequencei

Sequence statusi: Complete.

O22845-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRIFLLYNI LNSFLLSLVP KKLRTLFPLS WFDKTLHKNS PPSPSTMLPS
60 70 80 90 100
PSSSSAPTKR IDPSELKRVF QMFDKNGDGR ITKEELNDSL ENLGIYIPDK
110 120 130 140 150
DLTQMIHKID ANGDGCVDID EFESLYSSIV DEHHNDGETE EEDMKDAFNV
160 170 180 190 200
FDQDGDGFIT VEELKSVMAS LGLKQGKTLD GCKKMIMQVD ADGDGRVNYK
210
EFLQMMKGGG FSSSN
Length:215
Mass (Da):24,114
Last modified:June 1, 2002 - v2
Checksum:iA225E5A6E70D96C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF250344 mRNA Translation: AAG10150.1
AC002335 Genomic DNA Translation: AAB64310.2
AC004450 Genomic DNA Translation: AAM14938.1
CP002685 Genomic DNA Translation: AEC10248.1
AY062815 mRNA Translation: AAL32893.1
AY081574 mRNA Translation: AAM10136.1
AY087087 mRNA Translation: AAM64648.1
PIRiD84864
RefSeqiNP_565996.1, NM_129891.2
UniGeneiAt.21047

Genome annotation databases

EnsemblPlantsiAT2G43290.1; AT2G43290.1; AT2G43290
GeneIDi818931
GrameneiAT2G43290.1; AT2G43290.1; AT2G43290
KEGGiath:AT2G43290

Similar proteinsi

Entry informationi

Entry nameiCML5_ARATH
AccessioniPrimary (citable) accession number: O22845
Secondary accession number(s): Q9FV55
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: June 1, 2002
Last modified: April 25, 2018
This is version 128 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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