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O22834 (LRK53_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-type lectin-domain containing receptor kinase V.3
Short name=Arabidopsis thaliana lectin-receptor kinase c2
Short name=AthlecRK-c2
Short name=LecRK-V.3
EC=2.7.11.1
Gene names
Name:LECRK53
Synonyms:LECRKC2
Ordered Locus Names:At2g43690
ORF Names:F18O19.20
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length664 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

In the N-terminal section; belongs to the leguminous lectin family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2626 Potential
Chain27 – 664638Probable L-type lectin-domain containing receptor kinase V.3
PRO_0000403091

Regions

Topological domain27 – 278252Extracellular Potential
Transmembrane279 – 29921Helical; Potential
Topological domain300 – 664365Cytoplasmic Potential
Domain335 – 617283Protein kinase
Nucleotide binding341 – 3499ATP By similarity
Region28 – 250223Legume-lectin like

Sites

Active site4611Proton acceptor By similarity
Binding site3641ATP By similarity

Amino acid modifications

Glycosylation691N-linked (GlcNAc...) Potential
Glycosylation1161N-linked (GlcNAc...) Potential
Glycosylation1221N-linked (GlcNAc...) Potential
Glycosylation1741N-linked (GlcNAc...) Potential
Glycosylation1971N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O22834 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: F234E2645A8FFA6C

FASTA66474,398
        10         20         30         40         50         60 
MSMSCKINWL MVLVIIALSN LESSLGRLVF EGSAGLMNGF TTLTNTKKHA YGQAFNDEPF 

        70         80         90        100        110        120 
PFKNSVNGNM TSFSFTFFFA IVPEHIDKGS HGIAFVISPT RGIPGASADQ YLGIFNDTND 

       130        140        150        160        170        180 
GNSSNHIIAV ELDIHKDDEF GDIDDNHVGI NINGMRSIVS APAGYYDQNG QFKNLSLISG 

       190        200        210        220        230        240 
NLLRVTILYS QEEKQLNVTL SPAEEANVPK WPLLSLNKDL SPYLSKNMYI GFTASTGSVG 

       250        260        270        280        290        300 
AIHYMWMWYV FTFIIVPKLD FDIPTFPPYP KAESQVKLIV LVTFLTLALF VALAASALIV 

       310        320        330        340        350        360 
FFYKRHKKLL EVLEEWEVEC GPHRFSYKEL FNATNGFKQL LGEGGFGPVF KGTLSGSNAK 

       370        380        390        400        410        420 
IAVKRVSHDS SQGMRELLAE ISTIGRLRHP NLVRLLGYCR YKEELYLVYD FLPNGSLDKY 

       430        440        450        460        470        480 
LYGTSDQKQL SWSQRFKIIK DVASALSYLH HGWIHVVIHR DIKPANVLID DKMNASLGDF 

       490        500        510        520        530        540 
GLAKVYDQGY DPQTSRVAGT FGYMAPEIMR TGRPTMGTDV YAFGMFMLEV SCDRKLFEPR 

       550        560        570        580        590        600 
AESEEAILTN WAINCWENGD IVEAATERIR QDNDKGQLEL VLKLGVLCSH EAEEVRPDMA 

       610        620        630        640        650        660 
TVVKILNGVS ELPDNLLDIV RSEKLENWYE RYSKVIDPVT TEESIGNLAI TEPILPSGRP 


RLFL

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
[4]"Lectin receptor kinases in plants."
Barre A., Herve C., Lescure B., Rouge P.
Crit. Rev. Plant Sci. 21:379-399(2002)
Cited for: GENE FAMILY.
[5]"Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
Bouwmeester K., Govers F.
J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC002333 Genomic DNA. Translation: AAB64037.1.
CP002685 Genomic DNA. Translation: AEC10308.1.
IPIIPI00525653.
PIRC84869.
RefSeqNP_181897.1. NM_129931.1.
UniGeneAt.66343.

3D structure databases

HSSPHSSP built from PDB template 1DQ2 based on UniProtKB P02866.
ProteinModelPortalO22834.
SMRO22834. Positions 19-266, 278-603.
ModBaseSearch...

Protein-protein interaction databases

STRING3702.AT2G43690.1-P.

Proteomic databases

PaxDbO22834.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G43690.1; AT2G43690.1; AT2G43690.
GeneID818971.
KEGGath:AT2G43690.

Organism-specific databases

GeneFarm126. 4.
TAIRAt2g43690.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000116555.
InParanoidO22834.
OMAWYERYSK.
PhylomeDBO22834.
ProtClustDBCLSN2912902.

Gene expression databases

GenevestigatorO22834.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_cat_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF49899. ConA_like_lec_gl. 1 hit.
SSF56112. Kinase_like. 1 hit.
PROSITEPS00307. LECTIN_LEGUME_BETA. False negative.
PS00107. PROTEIN_KINASE_ATP. False negative.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLRK53_ARATH
AccessionPrimary (citable) accession number: O22834
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: January 1, 1998
Last modified: May 1, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·Documents