Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein LYK5

Gene

LYK5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

May recognize microbe-derived N-acetylglucosamine (NAG)-containing ligands.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei395ATPPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi357 – 365ATPPROSITE-ProRule annotation9

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • chitin binding Source: TAIR
  • protein homodimerization activity Source: TAIR
  • transmembrane receptor protein serine/threonine kinase activity Source: GO_Central

GO - Biological processi

  • cell surface receptor signaling pathway Source: GO_Central
  • cellular response to chitin Source: UniProtKB
  • innate immune response Source: TAIR
  • protein phosphorylation Source: GO_Central

Keywordsi

LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein LYK5
Alternative name(s):
LysM domain receptor-like kinase 5
LysM-containing receptor-like kinase 5
Gene namesi
Name:LYK5
Ordered Locus Names:At2g33580
ORF Names:F4P9.35
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G33580.
TAIRilocus:2050987. AT2G33580.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini27 – 277ExtracellularSequence analysisAdd BLAST251
Transmembranei278 – 298HelicalSequence analysisAdd BLAST21
Topological domaini299 – 664CytoplasmicSequence analysisAdd BLAST366

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000042083127 – 664Protein LYK5Add BLAST638

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi45N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi52 ↔ 114By similarity
Disulfide bondi58 ↔ 181By similarity
Glycosylationi81N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi111N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi112 ↔ 179By similarity
Glycosylationi125N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi129N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi144N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi213N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiO22808.
PRIDEiO22808.

PTM databases

SwissPalmiO22808.

Expressioni

Inductioni

Moderately induced by chitin oligomers (e.g. chitohexaose (6-mer) and chitooctaose (8-mer)).1 Publication

Gene expression databases

GenevisibleiO22808. AT.

Interactioni

GO - Molecular functioni

  • protein homodimerization activity Source: TAIR

Protein-protein interaction databases

BioGridi3270. 12 interactors.
STRINGi3702.AT2G33580.1.

Structurei

3D structure databases

ProteinModelPortaliO22808.
SMRiO22808.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini195 – 238LysMPROSITE-ProRule annotationAdd BLAST44
Domaini351 – 643Protein kinasePROSITE-ProRule annotationAdd BLAST293

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni135 – 141Chitin-bindingBy similarity7
Regioni164 – 170Chitin-bindingBy similarity7

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi235 – 270Pro-richAdd BLAST36

Domaini

The protein kinase domain is predicted to be catalytically inactive.

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IGC6. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000238861.
InParanoidiO22808.
OMAiQNPLHDS.
OrthoDBiEOG093607W7.
PhylomeDBiO22808.

Family and domain databases

Gene3Di1.20.5.100. 1 hit.
3.10.350.10. 3 hits.
InterProiView protein in InterPro
IPR021157. Cyt_c1_TM_anchor_C.
IPR011009. Kinase-like_dom_sf.
IPR018392. LysM_dom.
IPR036779. LysM_dom_sf.
IPR000719. Prot_kinase_dom.
PfamiView protein in Pfam
PF01476. LysM. 1 hit.
PF00069. Pkinase. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS51782. LYSM. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O22808-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAACTLHALS VTLFLLLFFA VSPAKAQQPY VNNHQLACEV RVYDNITNGF
60 70 80 90 100
TCNGPPSCRS YLTFWSQPPY NTADSIAKLL NVSAAEIQSI NNLPTATTRI
110 120 130 140 150
PTRELVVIPA NCSCSSSSGG FYQHNATYNL SGNRGDETYF SVANDTYQAL
160 170 180 190 200
STCQAMMSQN RYGERQLTPG LNLLVPLRCA CPTAKQTTAG FKYLLTYLVA
210 220 230 240 250
MGDSISGIAE MFNSTSAAIT EGNELTSDNI FFFTPVLVPL TTEPTKIVIS
260 270 280 290 300
PSPPPPPVVA TPPQTPVDPP GSSSSHKWIY IGIGIGAGLL LLLSILALCF
310 320 330 340 350
YKRRSKKKSL PSSLPEENKL FDSSTKQSIP TTTTTQWSID LSNSSEAFGL
360 370 380 390 400
KSAIESLTLY RFNDLQSATS NFSDENRIKG SVYRATINGD DAAVKVIKGD
410 420 430 440 450
VSSSEINLLK KLNHSNIIRL SGFCIREGTS YLVFEYSENG SISDWLHSSG
460 470 480 490 500
KKSLTWKQRV EIARDVAEAL DYLHNYITPP HIHKNLESTN ILLDSNFRAK
510 520 530 540 550
IANFGVARIL DEGDLDLQLT RHVEGTQGYL APEYVENGVI TSKLDVFAFG
560 570 580 590 600
VAVLELLSGR EAVTIHKKKE GEEEVEMLCK VINSVLGGEN VREKLKEFMD
610 620 630 640 650
PSLGNEYPLE LAYTMAQLAK SCVATDLNSR PSVTQVLTTL SMIVSSSIDW
660
EPSDDLLRSG SLGN
Length:664
Mass (Da):72,569
Last modified:January 1, 1998 - v1
Checksum:i4EF6E14FB1AE97E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002332 Genomic DNA. Translation: AAB80675.1.
CP002685 Genomic DNA. Translation: AEC08855.1.
AF370600 mRNA. Translation: AAK43919.1.
BT046191 mRNA. Translation: ACI49790.1.
PIRiC84747.
RefSeqiNP_180916.1. NM_128918.5.
UniGeneiAt.12134.

Genome annotation databases

EnsemblPlantsiAT2G33580.1; AT2G33580.1; AT2G33580.
GeneIDi817923.
GrameneiAT2G33580.1; AT2G33580.1; AT2G33580.
KEGGiath:AT2G33580.

Similar proteinsi

Entry informationi

Entry nameiLYK5_ARATH
AccessioniPrimary (citable) accession number: O22808
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2013
Last sequence update: January 1, 1998
Last modified: November 22, 2017
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families