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O22727 (DRL16_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable disease resistance protein At1g61190
Gene names
Ordered Locus Names:At1g61190
ORF Names:F11P17.9
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length967 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probable disease resistance protein By similarity.

Domain

The LRR repeats probably act as specificity determinant of pathogen recognition By similarity.

Sequence similarities

Belongs to the disease resistance NB-LRR family.

Contains 5 LRR (leucine-rich) repeats.

Contains 1 NB-ARC domain.

Ontologies

Keywords
   Biological processPlant defense
   DomainCoiled coil
Leucine-rich repeat
Repeat
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdefense response

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionADP binding

Inferred from electronic annotation. Source: InterPro

ATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 967967Probable disease resistance protein At1g61190
PRO_0000212748

Regions

Domain138 – 441304NB-ARC
Repeat516 – 53722LRR 1
Repeat538 – 55922LRR 2
Repeat562 – 58524LRR 3
Repeat586 – 60823LRR 4
Repeat609 – 63123LRR 5
Nucleotide binding180 – 1878ATP Potential
Coiled coil20 – 6849 Potential

Sequences

Sequence LengthMass (Da)Tools
O22727 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 9037FAA7BFEC7827

FASTA967111,532
        10         20         30         40         50         60 
MGNFVCIEIS GDQMLDRIIR CLCGKGYIRN LEKNLRALQR EMEDLRATQH EVQNKVAREE 

        70         80         90        100        110        120 
SRHQQRLEAV QVWLDRVNSI DIECKDLLSV SPVELQKLCL CGLCSKYVCS SYKYGKRVFL 

       130        140        150        160        170        180 
LLEEVTKLKS EGNFDEVSQP PPRSEVEERP TQPTIGQEEM LKKAWNRLME DGVGIMGLHG 

       190        200        210        220        230        240 
MGGVGKTTLF KKIHNKFAET GGTFDIVIWI VVSQGAKLSK LQEDIAEKLH LCDDLWKNKN 

       250        260        270        280        290        300 
ESDKATDIHR VLKGKRFVLM LDDIWEKVDL EAIGIPYPSE VNKCKVAFTT RDQKVCGQMG 

       310        320        330        340        350        360 
DHKPMQVKCL EPEDAWELFK NKVGDNTLRS DPVIVGLARE VAQKCRGLPL ALSCIGETMA 

       370        380        390        400        410        420 
SKTMVQEWEH AIDVLTRSAA EFSDMQNKIL PILKYSYDSL EDEHIKSCFL YCALFPEDDK 

       430        440        450        460        470        480 
IDTKTLINKW ICEGFIGEDQ VIKRARNKGY EMLGTLIRAN LLTNDRGFVK WHVVMHDVVR 

       490        500        510        520        530        540 
EMALWIASDF GKQKENYVVR ARVGLHEIPK VKDWGAVRRM SLMMNEIEEI TCESKCSELT 

       550        560        570        580        590        600 
TLFLQSNQLK NLSGEFIRYM QKLVVLDLSH NPDFNELPEQ ISGLVSLQYL DLSWTRIEQL 

       610        620        630        640        650        660 
PVGLKELKKL IFLNLCFTER LCSISGISRL LSLRWLSLRE SNVHGDASVL KELQQLENLQ 

       670        680        690        700        710        720 
DLRITESAEL ISLDQRLAKL ISVLRIEGFL QKPFDLSFLA SMENLYGLLV ENSYFSEINI 

       730        740        750        760        770        780 
KCRESETESS YLHINPKIPC FTNLTGLIIM KCHSMKDLTW ILFAPNLVNL DIRDSREVGE 

       790        800        810        820        830        840 
IINKEKAINL TSIITPFQKL ERLFLYGLPK LESIYWSPLP FPLLSNIVVK YCPKLRKLPL 

       850        860        870        880        890        900 
NATSVPLVEE FEIRMDPPEQ ENELEWEDED TKNRFLPSIK PLVRRLKIHY SGMGFLNVKN 

       910        920        930        940        950        960 
QNPRFFFYCF IYLLVVHLDC IIDLHSDTSG MCCVVHLDYV FHFPFVFPKT FCILFRLHFY 


TIKSLCV 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
+Additional computationally mapped references.

Web resources

NIB-LRRS

Functional and comparative genomics of disease resistance gene homologs

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC002294 Genomic DNA. Translation: AAB71476.1.
CP002684 Genomic DNA. Translation: AEE33801.1.
PIRG96637.
RefSeqNP_176314.1. NM_104800.1.
UniGeneAt.36514.
At.71478.

3D structure databases

ProteinModelPortalO22727.
SMRO22727. Positions 174-478, 508-666, 743-775, 797-839.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G61190.1-P.

Proteomic databases

PaxDbO22727.
PRIDEO22727.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G61190.1; AT1G61190.1; AT1G61190.
GeneID842412.
KEGGath:AT1G61190.

Organism-specific databases

TAIRAT1G61190.

Phylogenomic databases

eggNOGNOG249426.
HOGENOMHOG000238348.
InParanoidO22727.
OMAHINAVET.
PhylomeDBO22727.

Gene expression databases

GenevestigatorO22727.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR000767. Disease_R.
IPR001611. Leu-rich_rpt.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF13855. LRR_8. 1 hit.
PF00931. NB-ARC. 1 hit.
[Graphical view]
PRINTSPR00364. DISEASERSIST.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDRL16_ARATH
AccessionPrimary (citable) accession number: O22727
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: January 1, 1998
Last modified: June 11, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names