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O22719 (LHTL3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Lysine histidine transporter-like 3
Gene names
Ordered Locus Names:At1g61270
ORF Names:F11P17.1
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length451 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Amino acid transporter By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily. [View classification]

Sequence caution

The sequence AAB71468.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processAmino-acid transport
Transport
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processamino acid transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 451451Lysine histidine transporter-like 3
PRO_0000387973

Regions

Topological domain1 – 4040Cytoplasmic Potential
Transmembrane41 – 6121Helical; Potential
Topological domain62 – 632Extracellular Potential
Transmembrane64 – 8421Helical; Potential
Topological domain85 – 11531Cytoplasmic Potential
Transmembrane116 – 13621Helical; Potential
Topological domain137 – 15923Extracellular Potential
Transmembrane160 – 17718Helical; Potential
Topological domain178 – 1825Cytoplasmic Potential
Transmembrane183 – 20321Helical; Potential
Topological domain204 – 22724Extracellular Potential
Transmembrane228 – 24821Helical; Potential
Topological domain249 – 26921Cytoplasmic Potential
Transmembrane270 – 29021Helical; Potential
Topological domain291 – 30919Extracellular Potential
Transmembrane310 – 33021Helical; Potential
Topological domain331 – 35828Cytoplasmic Potential
Transmembrane359 – 37921Helical; Potential
Topological domain3801Extracellular Potential
Transmembrane381 – 40121Helical; Potential
Topological domain402 – 41312Cytoplasmic Potential
Transmembrane414 – 43421Helical; Potential
Topological domain435 – 45117Extracellular Potential

Sequences

Sequence LengthMass (Da)Tools
O22719 [UniParc].

Last modified November 3, 2009. Version 2.
Checksum: 949DE600442F66E1

FASTA45150,326
        10         20         30         40         50         60 
MKGIPSSSNQ ILNQDLVEDQ SFELEDWLPI TASRNANWYY SAFHNVTAIV GAGVLGLPYA 

        70         80         90        100        110        120 
MSELGWGPGV VVLILSWVIT LYTFWQMIEM HEMFEGKRFD RYHELGQAAF GKKLGLYIVV 

       130        140        150        160        170        180 
PLQLLVETSA CIVYMVTGGE SLKKIHQLSV GDYECRKLKV RHFILIFASS QFVLSLLKNF 

       190        200        210        220        230        240 
NSISGVSLVA AVMSMSYSTI AWVASLTKGV ANNVEYGYKR RNNTSVPLAF LGALGEMAFA 

       250        260        270        280        290        300 
YAGHNVVLEI QATIPSTPEN PSKRPMWKGA IVAYIIVAFC YFPVALVGFW TFGNNVEENI 

       310        320        330        340        350        360 
LKTLRGPKGL IIVANIFVII HLMGSYQVYA MPVFDMIESV MIKKWHFSPT RVLRFTIRWT 

       370        380        390        400        410        420 
FVAATMGIAV ALPHFSALLS FFGGFIFAPT TYFIPCIIWL ILKKPKRFSL SWCINWICII 

       430        440        450 
LGVLVMIIAP IGGLAKLMNA LKQPDSSCKS T

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Selective expression of a novel high-affinity transport system for acidic and neutral amino acids in the tapetum cells of Arabidopsis flowers."
Lee Y.-H., Tegeder M.
Plant J. 40:60-74(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
Strain: cv. C24.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC002294 Genomic DNA. Translation: AAB71468.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33815.1.
IPIIPI00526245.
RefSeqNP_176322.1. NM_104808.1.
UniGeneAt.52299.

3D structure databases

ProteinModelPortalO22719.
ModBaseSearch...

Protein-protein interaction databases

STRING3702.AT1G61270.1-P.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G61270.1; AT1G61270.1; AT1G61270.
GeneID842421.
KEGGath:AT1G61270.

Organism-specific databases

TAIRAt1g61270.

Phylogenomic databases

eggNOGNOG241385.
HOGENOMHOG000241295.
InParanoidO22719.
OMACINWICI.
PhylomeDBO22719.
ProtClustDBCLSN2914405.

Family and domain databases

InterProIPR013057. AA_transpt_TM.
[Graphical view]
PfamPF01490. Aa_trans. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLHTL3_ARATH
AccessionPrimary (citable) accession number: O22719
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: November 3, 2009
Last modified: May 1, 2013
This is version 57 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

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