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Protein

Cytochrome B5-like protein

Gene

CB5LP

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi81 – 811Iron (heme axial ligand)PROSITE-ProRule annotation
Metal bindingi104 – 1041Iron (heme axial ligand)PROSITE-ProRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome B5-like protein1 Publication
Short name:
AtCb5LP1 Publication
Alternative name(s):
Cytochrome b5 isoform F1 Publication
Short name:
AtCb5-F1 Publication
Gene namesi
Name:CB5LP1 Publication
Synonyms:CB5-F1 Publication
Ordered Locus Names:At1g60660Imported
ORF Names:F8A5.18Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G60660.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 121121Cytochrome B5-like proteinPRO_0000430956Add
BLAST

Proteomic databases

PaxDbiO22704.
PRIDEiO22704.

PTM databases

iPTMnetiO22704.

Expressioni

Gene expression databases

GenevisibleiO22704. AT.

Interactioni

Protein-protein interaction databases

BioGridi27584. 1 interaction.
IntActiO22704. 1 interaction.
STRINGi3702.AT1G60660.1.

Structurei

3D structure databases

ProteinModelPortaliO22704.
SMRiO22704. Positions 47-96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini46 – 12176Cytochrome b5 heme-bindingPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cytochrome b5 family.Curated
Contains 1 cytochrome b5 heme-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0537. Eukaryota.
COG5274. LUCA.
HOGENOMiHOG000039853.
InParanoidiO22704.
OMAiHNKRNDC.
PhylomeDBiO22704.

Family and domain databases

Gene3Di3.10.120.10. 1 hit.
InterProiIPR001199. Cyt_B5-like_heme/steroid-bd.
IPR018506. Cyt_B5_heme-BS.
[Graphical view]
PfamiPF00173. Cyt-b5. 1 hit.
[Graphical view]
PRINTSiPR00363. CYTOCHROMEB5.
SMARTiSM01117. Cyt-b5. 1 hit.
[Graphical view]
SUPFAMiSSF55856. SSF55856. 1 hit.
PROSITEiPS00191. CYTOCHROME_B5_1. 1 hit.
PS50255. CYTOCHROME_B5_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O22704-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAVIGLLLG FLVSALFLIQ GKRRRTNDNQ EKKRSSSEPV EDVVRPKSYS
60 70 80 90 100
KSEVAVHNKR NDCWIIIKDK VYDITSYVEE HPGGDAILDH AGDDSTDGFF
110 120
GPQHATRVFD MIEDFYIGEL H
Length:121
Mass (Da):13,709
Last modified:January 1, 1998 - v1
Checksum:i59E729C7EBAAA525
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002292 Genomic DNA. Translation: AAB71978.1.
CP002684 Genomic DNA. Translation: AEE33716.1.
AY049297 mRNA. Translation: AAK83639.1.
AY133575 mRNA. Translation: AAM91405.1.
PIRiH96631.
RefSeqiNP_176265.1. NM_104749.2.
UniGeneiAt.19208.

Genome annotation databases

EnsemblPlantsiAT1G60660.1; AT1G60660.1; AT1G60660.
GeneIDi842360.
GrameneiAT1G60660.1; AT1G60660.1; AT1G60660.
KEGGiath:AT1G60660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002292 Genomic DNA. Translation: AAB71978.1.
CP002684 Genomic DNA. Translation: AEE33716.1.
AY049297 mRNA. Translation: AAK83639.1.
AY133575 mRNA. Translation: AAM91405.1.
PIRiH96631.
RefSeqiNP_176265.1. NM_104749.2.
UniGeneiAt.19208.

3D structure databases

ProteinModelPortaliO22704.
SMRiO22704. Positions 47-96.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi27584. 1 interaction.
IntActiO22704. 1 interaction.
STRINGi3702.AT1G60660.1.

PTM databases

iPTMnetiO22704.

Proteomic databases

PaxDbiO22704.
PRIDEiO22704.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G60660.1; AT1G60660.1; AT1G60660.
GeneIDi842360.
GrameneiAT1G60660.1; AT1G60660.1; AT1G60660.
KEGGiath:AT1G60660.

Organism-specific databases

TAIRiAT1G60660.

Phylogenomic databases

eggNOGiKOG0537. Eukaryota.
COG5274. LUCA.
HOGENOMiHOG000039853.
InParanoidiO22704.
OMAiHNKRNDC.
PhylomeDBiO22704.

Miscellaneous databases

PROiO22704.

Gene expression databases

GenevisibleiO22704. AT.

Family and domain databases

Gene3Di3.10.120.10. 1 hit.
InterProiIPR001199. Cyt_B5-like_heme/steroid-bd.
IPR018506. Cyt_B5_heme-BS.
[Graphical view]
PfamiPF00173. Cyt-b5. 1 hit.
[Graphical view]
PRINTSiPR00363. CYTOCHROMEB5.
SMARTiSM01117. Cyt-b5. 1 hit.
[Graphical view]
SUPFAMiSSF55856. SSF55856. 1 hit.
PROSITEiPS00191. CYTOCHROME_B5_1. 1 hit.
PS50255. CYTOCHROME_B5_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Functional association of cell death suppressor, Arabidopsis Bax inhibitor-1, with fatty acid 2-hydroxylation through cytochrome b(5)."
    Nagano M., Ihara-Ohori Y., Imai H., Inada N., Fujimoto M., Tsutsumi N., Uchimiya H., Kawai-Yamada M.
    Plant J. 58:122-134(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE.
  5. "Higher plant cytochrome b5 polypeptides modulate fatty acid desaturation."
    Kumar R., Tran L.S., Neelakandan A.K., Nguyen H.T.
    PLoS ONE 7:E31370-E31370(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE.

Entry informationi

Entry nameiCYP5F_ARATH
AccessioniPrimary (citable) accession number: O22704
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 26, 2014
Last sequence update: January 1, 1998
Last modified: June 8, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.