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Protein

Cyanate hydratase

Gene

CYN

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.UniRule annotation

Catalytic activityi

Cyanate + HCO3- + 2 H+ = NH3 + 2 CO2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei91UniRule annotation1
Active sitei94UniRule annotation1
Active sitei117UniRule annotation1

GO - Molecular functioni

  • cyanate hydratase activity Source: TAIR
  • DNA binding Source: InterPro
  • identical protein binding Source: TAIR

GO - Biological processi

  • cyanate catabolic process Source: TAIR
  • response to salt stress Source: TAIR

Keywordsi

Molecular functionLyase

Enzyme and pathway databases

BioCyciARA:AT3G23490-MONOMER.
MetaCyc:AT3G23490-MONOMER.
BRENDAi4.2.1.104. 399.

Names & Taxonomyi

Protein namesi
Recommended name:
Cyanate hydrataseUniRule annotation (EC:4.2.1.104UniRule annotation)
Short name:
CyanaseUniRule annotation
Alternative name(s):
Cyanate hydrolaseUniRule annotation
Cyanate lyaseUniRule annotation
Gene namesi
Name:CYNUniRule annotation
Ordered Locus Names:At3g23490
ORF Names:MEE5.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRilocus:2088727. AT3G23490.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: TAIR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001875341 – 168Cyanate hydrataseAdd BLAST168

Proteomic databases

PaxDbiO22683.

PTM databases

iPTMnetiO22683.

Expressioni

Gene expression databases

ExpressionAtlasiO22683. baseline and differential.
GenevisibleiO22683. AT.

Interactioni

GO - Molecular functioni

  • identical protein binding Source: TAIR

Protein-protein interaction databases

BioGridi7262. 1 interactor.
STRINGi3702.AT3G23490.1.

Structurei

3D structure databases

ProteinModelPortaliO22683.
SMRiO22683.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyanase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IWK0. Eukaryota.
COG1513. LUCA.
HOGENOMiHOG000043436.
InParanoidiO22683.
KOiK01725.
OMAiPPMRSYD.
OrthoDBiEOG09360QQX.
PhylomeDBiO22683.

Family and domain databases

CDDicd00559. Cyanase_C. 1 hit.
Gene3Di3.30.1160.10. 1 hit.
HAMAPiMF_00535. Cyanate_hydrat. 1 hit.
InterProiView protein in InterPro
IPR008076. Cyanase.
IPR003712. Cyanate_lyase_C.
IPR010982. Lambda_DNA-bd_dom.
PANTHERiPTHR34186. PTHR34186. 1 hit.
PfamiView protein in Pfam
PF02560. Cyanate_lyase. 1 hit.
PIRSFiPIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSiPR01693. CYANASE.
SMARTiView protein in SMART
SM01116. Cyanate_lyase. 1 hit.
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF55234. SSF55234. 1 hit.
TIGRFAMsiTIGR00673. cynS. 1 hit.

Sequencei

Sequence statusi: Complete.

O22683-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAAKKQSVT NQLLAVKSAS GKTFSQLAAE TGLTNVYVAQ LLRRQAQLKP
60 70 80 90 100
DTVPKLKEAL PALTDELIGD MMSPPWRSYD PNLIQEPTIY RLNEAVMHFG
110 120 130 140 150
ESIKEIINED FGDGIMSAID FYCSVDKIKG VDGNNRVVVT LDGKYLSHSE
160
QRTENMVSRL NLKGGTSE
Length:168
Mass (Da):18,592
Last modified:January 1, 1998 - v1
Checksum:iB31E891C80A7789E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004568 mRNA. Translation: BAA21660.1.
AB015748 Genomic DNA. Translation: BAA31224.1.
AP000374 Genomic DNA. Translation: BAB01741.1.
CP002686 Genomic DNA. Translation: AEE76771.1.
CP002686 Genomic DNA. Translation: ANM65955.1.
AF410298 mRNA. Translation: AAK95284.1.
AY093708 mRNA. Translation: AAM10332.1.
RefSeqiNP_001327887.1. NM_001338643.1.
NP_188991.1. NM_113252.4.
UniGeneiAt.20785.

Genome annotation databases

EnsemblPlantsiAT3G23490.1; AT3G23490.1; AT3G23490.
AT3G23490.2; AT3G23490.2; AT3G23490.
GeneIDi821930.
GrameneiAT3G23490.1; AT3G23490.1; AT3G23490.
AT3G23490.2; AT3G23490.2; AT3G23490.
KEGGiath:AT3G23490.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004568 mRNA. Translation: BAA21660.1.
AB015748 Genomic DNA. Translation: BAA31224.1.
AP000374 Genomic DNA. Translation: BAB01741.1.
CP002686 Genomic DNA. Translation: AEE76771.1.
CP002686 Genomic DNA. Translation: ANM65955.1.
AF410298 mRNA. Translation: AAK95284.1.
AY093708 mRNA. Translation: AAM10332.1.
RefSeqiNP_001327887.1. NM_001338643.1.
NP_188991.1. NM_113252.4.
UniGeneiAt.20785.

3D structure databases

ProteinModelPortaliO22683.
SMRiO22683.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi7262. 1 interactor.
STRINGi3702.AT3G23490.1.

PTM databases

iPTMnetiO22683.

Proteomic databases

PaxDbiO22683.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G23490.1; AT3G23490.1; AT3G23490.
AT3G23490.2; AT3G23490.2; AT3G23490.
GeneIDi821930.
GrameneiAT3G23490.1; AT3G23490.1; AT3G23490.
AT3G23490.2; AT3G23490.2; AT3G23490.
KEGGiath:AT3G23490.

Organism-specific databases

AraportiAT3G23490.
TAIRilocus:2088727. AT3G23490.

Phylogenomic databases

eggNOGiENOG410IWK0. Eukaryota.
COG1513. LUCA.
HOGENOMiHOG000043436.
InParanoidiO22683.
KOiK01725.
OMAiPPMRSYD.
OrthoDBiEOG09360QQX.
PhylomeDBiO22683.

Enzyme and pathway databases

BioCyciARA:AT3G23490-MONOMER.
MetaCyc:AT3G23490-MONOMER.
BRENDAi4.2.1.104. 399.

Miscellaneous databases

PROiPR:O22683.

Gene expression databases

ExpressionAtlasiO22683. baseline and differential.
GenevisibleiO22683. AT.

Family and domain databases

CDDicd00559. Cyanase_C. 1 hit.
Gene3Di3.30.1160.10. 1 hit.
HAMAPiMF_00535. Cyanate_hydrat. 1 hit.
InterProiView protein in InterPro
IPR008076. Cyanase.
IPR003712. Cyanate_lyase_C.
IPR010982. Lambda_DNA-bd_dom.
PANTHERiPTHR34186. PTHR34186. 1 hit.
PfamiView protein in Pfam
PF02560. Cyanate_lyase. 1 hit.
PIRSFiPIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSiPR01693. CYANASE.
SMARTiView protein in SMART
SM01116. Cyanate_lyase. 1 hit.
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF55234. SSF55234. 1 hit.
TIGRFAMsiTIGR00673. cynS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYNS_ARATH
AccessioniPrimary (citable) accession number: O22683
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 31, 2002
Last sequence update: January 1, 1998
Last modified: May 10, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.