Reviewed, UniProtKB/Swiss-Prot O22616 (DCOR_SOLLC)

Names and origin

Protein names

Recommended name:
    Ornithine decarboxylase
      Short name=ODC
    EC=4.1.1.17
Alternative name(s):
    LeODC

Gene names

Name:

ODC

Organism

Solanum lycopersicum (Tomato) (Lycopersicon esculentum)

Taxonomic identifier

4081 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length	431 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	L-ornithine = putrescine + CO2.
Cofactor	Pyridoxal phosphate.
Pathway	Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.
Tissue specificity	High expression in roots, shoot tips and whole flowers at anthesis. Lower expression in stems and the lowest in adult leaves. Ref.2
Developmental stage	Transient induction at 8 days post-anthesis. ODC activity seems to be related to active cell division. Ref.2
Sequence similarities	Belongs to the Orn/Lys/Arg decarboxylase class-II family.

Ontologies

Keywords
Biological process	Polyamine biosynthesis
Ligand	Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological process	polyamine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ornithine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 431	431	Ornithine decarboxylase		PRO_0000239255
Sites
	Active site	376	1	Proton donor; shared with dimeric partner By similarity
Amino acid modifications
	Modified residue	94	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	O22616-1 [UniParc]. Last modified March 1, 2001. Version 2. Checksum: B126D4FECEAE305D	FASTA	431	46,647
	10 20 30 40 50 60 MAGQTVIVSG LNPAAILQST IGGAPVAAAA ENGHTRKVVP LSKDALQDFM VSIITQKLQD 70 80 90 100 110 120 DKQPFYVLDL GEVVSLMEQW NSALPNIRPF YAVKCNPEPS FLSMLSAMGS NFDCASRAEI 130 140 150 160 170 180 EYVLSHGISP DRIVFANPCK PESDIIFAEK IGVNLTTYDS EDEVYKIRKH HPKCELLLRI 190 200 210 220 230 240 KPMTDGNARC PMGPKYGALP EEIEPLLRTA QAARLTVSGV SFHIGSGDAD SNAYLGAIAA 250 260 270 280 290 300 AKQVFETAAQ LGMPKMTVLD IGGGFTSGHQ FTTAAPAVKS ALETHFHDFP ELTIIAEPGR 310 320 330 340 350 360 FFAETAFTLA TTIIGKRVRG ELKEYWINDG LYGSMNCVLY DHATVTATPL ACMSNRNNLN 370 380 390 400 410 420 CGGSKTFPST VFGPTCDALD TVLRDYQLPE LQVNDWLIFP NMGAYTKAAG SNFNGFNTSA 430 IVTHLAYAYP N

References

[1]	Kwak S.H., Lee S.H. Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Pink ball. Tissue: Root.
[2]	"Expression of ornithine decarboxylase is transiently increased by pollination, 2,4-dichlorophenoxyacetic acid, and gibberellic acid in tomato ovaries." Alabadi D., Carbonell J. Plant Physiol. 118:323-328(1998) [PubMed: 9733552] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE, TISSUE SPECIFICITY. Strain: cv. Rutgers. Tissue: Ovary.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF029349 mRNA. Translation: AAB82301.2. AF030292 mRNA. Translation: AAC61845.1.
UniGene	Les.3525
3D structure databases
HSSP	HSSP built from PDB template 1NJJ based on UniProtKB Q9TZZ6.
ModBase	Search...
Enzyme and pathway databases
BRENDA	4.1.1.17. 281054.
Family and domain databases
InterPro	IPR000183. De-COase2. IPR002433. Orn_de-COase. [Graphical view]
Pfam	PF02784. Orn_Arg_deC_N. 1 hit. PF00278. Orn_DAP_Arg_deC. 1 hit. [Graphical view]
PRINTS	PR01179. ODADCRBXLASE. PR01182. ORNDCRBXLASE.
PROSITE	PS00878. ODR_DC_2_1. 1 hit. PS00879. ODR_DC_2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DCOR_SOLLC

Accession

Primary (citable) accession number: O22616
Secondary accession number(s): O82420

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	March 1, 2001
Last modified:	June 16, 2009
This is version 51 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)