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Protein

Heat stress transcription factor B-3

Gene

HSFB3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi38 – 132By similarityAdd BLAST95

GO - Molecular functioni

  • DNA binding transcription factor activity Source: TAIR
  • sequence-specific DNA binding Source: InterPro

GO - Biological processi

  • response to cadmium ion Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processStress response, Transcription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-ATH-3371453 Regulation of HSF1-mediated heat shock response
R-ATH-3371511 HSF1 activation
R-ATH-3371568 Attenuation phase
R-ATH-3371571 HSF1-dependent transactivation

Names & Taxonomyi

Protein namesi
Recommended name:
Heat stress transcription factor B-3
Short name:
AtHsfB3
Alternative name(s):
AtHsf-05
Gene namesi
Name:HSFB3
Synonyms:HSF05
Ordered Locus Names:At2g41690
ORF Names:T32G6.21
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi

Organism-specific databases

AraportiAT2G41690
TAIRilocus:2062698 AT2G41690

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002708121 – 244Heat stress transcription factor B-3Add BLAST244

Post-translational modificationi

Exhibits temperature-dependent phosphorylation.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiO22230

Expressioni

Gene expression databases

ExpressionAtlasiO22230 baseline and differential
GenevisibleiO22230 AT

Interactioni

Subunit structurei

Homotrimer.By similarity

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiO22230, 21 interactors
STRINGi3702.AT2G41690.1

Structurei

3D structure databases

ProteinModelPortaliO22230
SMRiO22230
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni173 – 218Hydrophobic repeat HR-A/BAdd BLAST46

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi202 – 208Nuclear localization signalSequence analysis7
Motifi236 – 243Nuclear export signalSequence analysis8

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi37 – 40Poly-Pro4

Domaini

The hydrophobic-rich region (HR-A/B) corresponds to the oligomerization domain.

Sequence similaritiesi

Belongs to the HSF family. Class B subfamily.Curated

Phylogenomic databases

eggNOGiKOG0627 Eukaryota
COG5169 LUCA
HOGENOMiHOG000242480
InParanoidiO22230
KOiK09419
OMAiVTTIRWE
OrthoDBiEOG09360JWU
PhylomeDBiO22230

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000232 HSF_DNA-bd
IPR027725 HSF_fam
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR10015 PTHR10015, 1 hit
PfamiView protein in Pfam
PF00447 HSF_DNA-bind, 1 hit
PRINTSiPR00056 HSFDOMAIN
SMARTiView protein in SMART
SM00415 HSF, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00434 HSF_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

O22230-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDAGEHLRC NDNVNDEERL PLEFMIGNST STAELQPPPP FLVKTYKVVE
60 70 80 90 100
DPTTDGVISW NEYGTGFVVW QPAEFARDLL PTLFKHCNFS SFVRQLNTYG
110 120 130 140 150
FRKVTTIRWE FSNEMFRKGQ RELMSNIRRR KSQHWSHNKS NHQVVPTTTM
160 170 180 190 200
VNQEGHQRIG IDHHHEDQQS SATSSSFVYT ALLDENKCLK NENELLSCEL
210 220 230 240
GKTKKKCKQL MELVERYRGE DEDATDESDD EEDEGLKLFG VKLE
Length:244
Mass (Da):28,308
Last modified:January 1, 1998 - v1
Checksum:iFC335FFF2705E948
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002510 Genomic DNA Translation: AAB84350.1
CP002685 Genomic DNA Translation: AEC10016.1
BT029452 mRNA Translation: ABK59681.1
PIRiT00825
RefSeqiNP_181700.1, NM_129732.2
UniGeneiAt.53095

Genome annotation databases

EnsemblPlantsiAT2G41690.1; AT2G41690.1; AT2G41690
GeneIDi818767
GrameneiAT2G41690.1; AT2G41690.1; AT2G41690
KEGGiath:AT2G41690

Entry informationi

Entry nameiHSFB3_ARATH
AccessioniPrimary (citable) accession number: O22230
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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