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O22047 (CHSE_IPOPU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chalcone synthase E

EC=2.3.1.74
Alternative name(s):
Naringenin-chalcone synthase E
Short name=CHS-E
Gene names
Name:CHSE
OrganismIpomoea purpurea (Common morning glory) (Pharbitis purpurea)
Taxonomic identifier4121 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesConvolvulaceaeIpomoeeaeIpomoea

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activity

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathway

Secondary metabolite biosynthesis; flavonoid biosynthesis.

Sequence similarities

Belongs to the chalcone/stilbene synthases family.

Ontologies

Keywords
   Biological processFlavonoid biosynthesis
   Molecular functionAcyltransferase
Transferase
Gene Ontology (GO)
   Biological_processflavonoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionnaringenin-chalcone synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 389389Chalcone synthase E
PRO_0000215995

Sites

Active site1641 By similarity

Sequences

Sequence LengthMass (Da)Tools
O22047 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 0CC81302CCA8A56A

FASTA38942,677
        10         20         30         40         50         60 
MVTVEEVRKA QRAQGPATIM AIGTSTPQNC VDQSTYPDYY FRITNSEHLV ELKEKFKRMC 

        70         80         90        100        110        120 
EKSMIKKRYM YLTEEILTEN PNICAYMAPS LDARQDIVVV EVPKLGKEAA QKAIKEWGQP 

       130        140        150        160        170        180 
KSKITHLVFC TTSGVDMPGA DYQLTKLLGL QPSVKRFMMY QQGCFAGGTV IRLAKDLAEN 

       190        200        210        220        230        240 
NKGARVLVVC SEITAVTFRG PSDAHLDSLV GQALFGDGAA ALIIGSDPDP DLERPLFQLV 

       250        260        270        280        290        300 
SAAQTILPDS GGAIDGHLRE VGLTFHLLKD VPGLISKHIE KSLNEAFQPL GIRDWNSLFW 

       310        320        330        340        350        360 
IAHPGGPAIL DQVEEKLELK PEKLRATRHV LSEYGNMSSA CVLFILDEMR KASSKEGLNT 

       370        380 
TGEGLEWGVL FGFGPGLTVE TVVLHSVSA 

« Hide

References

[1]"Identification of new chalcone synthase genes for flower pigmentation in the Japanese and common morning glories."
Fukada-Tanaka S., Hoshino A., Hisatomi Y., Habu Y., Hasebe M., Iida S.
Plant Cell Physiol. 38:754-758(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. FR-35.
Tissue: Flower bud.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB001827 mRNA. Translation: BAA21789.1.
PIRT07799.

3D structure databases

ProteinModelPortalO22047.
SMRO22047. Positions 3-388.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00154.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFPIRSF000451. PKS_III. 1 hit.
SUPFAMSSF53901. SSF53901. 2 hits.
PROSITEPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHSE_IPOPU
AccessionPrimary (citable) accession number: O22047
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: January 1, 1998
Last modified: February 19, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways