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O22046

- CHSE_IPONI

UniProt

O22046 - CHSE_IPONI

Protein

Chalcone synthase E

Gene

CHSE

Organism
Ipomoea nil (Japanese morning glory) (Pharbitis nil)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    • Comment

    Functioni

    The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chalcone synthase E (EC:2.3.1.74)
    Alternative name(s):
    Naringenin-chalcone synthase E
    Short name:
    CHS-E
    Gene namesi
    Name:CHSE
    OrganismiIpomoea nil (Japanese morning glory) (Pharbitis nil)
    Taxonomic identifieri35883 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesConvolvulaceaeIpomoeeaeIpomoea

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 389389Chalcone synthase EPRO_0000216038Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliO22046.
    SMRiO22046. Positions 3-388.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chalcone/stilbene synthases family.Curated

    Family and domain databases

    Gene3Di3.40.47.10. 2 hits.
    InterProiIPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000451. PKS_III. 1 hit.
    SUPFAMiSSF53901. SSF53901. 2 hits.
    PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O22046-1 [UniParc]FASTAAdd to Basket

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    MVTVEEVRKA QRAQGPATIM AIGTSTPQNC VDQSTYPDYY FRITNSEHLV    50
    ELKEKFKRMC EKSMIKKRYM YLTEEILKEN PNICAYMAPS LDARQDIVVV 100
    EVPKLGKEAA QKAIKEWGQP KSKITHLVFC TTSGVDMPGA DYQLTKLLGL 150
    QPSVKRFMMY QQGCFAGGTV IRLAKDLAEN NKGARVLVVC SEITAVTFRG 200
    PSDAHLDSLV GQALFGDGAA ALIIGSDPDP DLERPLFQLV SAAQTILPDS 250
    GGAIDGHLRE VGLTFHLLKD VPGLISKHIE KSLNEAFQPL GIHDWNSLFW 300
    IAHPGGPAIL DQVEEKLELK PEKLRATRHV LSEYGNMSSA CVLFILDEMR 350
    KASSKEGLNT TGEGLEWGVL FGFGPGLTVE TVVLHSVSA 389
    Length:389
    Mass (Da):42,685
    Last modified:January 1, 1998 - v1
    Checksum:i0FC0E014B9CC0312
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB001819 mRNA. Translation: BAA21788.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB001819 mRNA. Translation: BAA21788.1 .

    3D structure databases

    ProteinModelPortali O22046.
    SMRi O22046. Positions 3-388.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Family and domain databases

    Gene3Di 3.40.47.10. 2 hits.
    InterProi IPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000451. PKS_III. 1 hit.
    SUPFAMi SSF53901. SSF53901. 2 hits.
    PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of new chalcone synthase genes for flower pigmentation in the Japanese and common morning glories."
      Fukada-Tanaka S., Hoshino A., Hisatomi Y., Habu Y., Hasebe M., Iida S.
      Plant Cell Physiol. 38:754-758(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. KK/ZSK-2.
      Tissue: Flower bud.

    Entry informationi

    Entry nameiCHSE_IPONI
    AccessioniPrimary (citable) accession number: O22046
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1999
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3