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O22045 (CHSD_IPONI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chalcone synthase D

EC=2.3.1.74
Alternative name(s):
Naringenin-chalcone synthase D
Short name=CHS-D
Gene names
Name:CHSD
OrganismIpomoea nil (Japanese morning glory) (Pharbitis nil)
Taxonomic identifier35883 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesConvolvulaceaeIpomoeeaeIpomoea

Protein attributes

Sequence length388 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activity

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathway

Secondary metabolite biosynthesis; flavonoid biosynthesis.

Sequence similarities

Belongs to the chalcone/stilbene synthases family.

Ontologies

Keywords
   Biological processFlavonoid biosynthesis
   Molecular functionAcyltransferase
Transferase
Gene Ontology (GO)
   Biological_processflavonoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionnaringenin-chalcone synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 388388Chalcone synthase D
PRO_0000216037

Sites

Active site1641 By similarity

Sequences

Sequence LengthMass (Da)Tools
O22045 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 1BE2CDB2C2DABDEE

FASTA38842,183
        10         20         30         40         50         60 
MVTVEEVRKA QRAEGPATIL AIGTATPANC VDQSTYPDYY FRITNSDHMT DLKQKFQRMC 

        70         80         90        100        110        120 
DKSMITKRYM HLTEEILKEN PSFCEYMAPS LDARQDIVVV EVPKLGKEAA QSAIKEWGQP 

       130        140        150        160        170        180 
KSKITHVIFC TTSGVDMPGA DYQLTKLLGL RPSVKRLMMY QQGCFAGGTV LRVAKDLAEN 

       190        200        210        220        230        240 
NKAARVLVVC SEITVVTFRG PNETHLDSLV GQALFGDGAA AIIVGSDPTP AEKPLFQLVS 

       250        260        270        280        290        300 
AAQTLAPDSC GAIDGHLREV GLTFHLLKDV PSIVSNNIEK CLSEAFNPLG ISDWNSIFWI 

       310        320        330        340        350        360 
AHPGGPAILD QVEDKLGLKP EKLRATRHVL SEYGNMSSAC VLFILDEMRK ASSNDGLGTT 

       370        380 
GEGLEWGVLF GFGPGLTIET VVLHSVPA 

« Hide

References

[1]"Identification of new chalcone synthase genes for flower pigmentation in the Japanese and common morning glories."
Fukada-Tanaka S., Hoshino A., Hisatomi Y., Habu Y., Hasebe M., Iida S.
Plant Cell Physiol. 38:754-758(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. KK/ZSK-2.
Tissue: Flower bud.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB001818 mRNA. Translation: BAA21787.1.

3D structure databases

ProteinModelPortalO22045.
SMRO22045. Positions 3-386.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00154.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFPIRSF000451. PKS_III. 1 hit.
SUPFAMSSF53901. SSF53901. 2 hits.
PROSITEPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHSD_IPONI
AccessionPrimary (citable) accession number: O22045
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: January 1, 1998
Last modified: February 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways