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O22000 (DCTD_BPMD2) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Deoxycytidylate deaminase

EC=3.5.4.12
Alternative name(s):
dCMP deaminase
Gene names
Name:36.1
Synonyms:G1
OrganismMycobacterium phage D29 (Mycobacteriophage D29) [Complete proteome]
Taxonomic identifier28369 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridaeL5likevirus
Virus hostMycobacterium [TaxID: 1763]

Protein attributes

Sequence length128 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

dCMP + H2O = dUMP + NH3.

Sequence similarities

Belongs to the cytidine and deoxycytidylate deaminase family.

Ontologies

Keywords
   Biological processNucleotide biosynthesis
   LigandMetal-binding
Zinc
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processnucleotide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functiondCMP deaminase activity

Inferred from electronic annotation. Source: UniProtKB-EC

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 128128Deoxycytidylate deaminase
PRO_0000171698

Sites

Active site831Proton donor By similarity
Metal binding811Zinc; catalytic By similarity
Metal binding1071Zinc; catalytic By similarity
Metal binding1101Zinc; catalytic By similarity

Sequences

Sequence LengthMass (Da)Tools
O22000 [UniParc].

Last modified December 15, 1998. Version 2.
Checksum: F78F1BA3DB5184D4

FASTA12813,539
        10         20         30         40         50         60 
MSRPDWDEYF LGIATAAAQR SDCERSKVGA VVVKDRRVRG TGYNGAPAGA AGCSTCPRRL 

        70         80         90        100        110        120 
SGAVPGVSDY SSGATRCVAV HAEANALLYC DREDLIGATL YVTREPCYAC SNLIAASGIE 


RVVYPKES 

« Hide

References

« Hide 'large scale' references
[1]"Genome structure of mycobacteriophage D29: implications for phage evolution."
Ford M.E., Sarkis G.J., Belanger A.E., Hendrix R.W., Hatfull G.F.
J. Mol. Biol. 279:143-164(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5."
Ribeiro G., Viveiros M., David H.L., Costa J.V.
Microbiology 143:2701-2708(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 51-128.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF022214 Genomic DNA. Translation: AAC18478.1.
U81553 Genomic DNA. Translation: AAB69099.1.
PIRC72804.
RefSeqNP_046853.1. NC_001900.1.

3D structure databases

ProteinModelPortalO22000.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1261565.

Phylogenomic databases

ProtClustDBCLSP2343399.

Family and domain databases

InterProIPR016192. APOBEC/CMP_deaminase_Zn-bd.
IPR002125. CMP_dCMP_Zn-bd.
IPR015517. Cyt_deaminase.
IPR016193. Cytidine_deaminase-like.
IPR016473. dCMP_deaminase.
[Graphical view]
PANTHERPTHR11086. PTHR11086. 1 hit.
PfamPF00383. dCMP_cyt_deam_1. 1 hit.
[Graphical view]
PIRSFPIRSF006019. dCMP_deaminase. 1 hit.
SUPFAMSSF53927. SSF53927. 1 hit.
PROSITEPS00903. CYT_DCMP_DEAMINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDCTD_BPMD2
AccessionPrimary (citable) accession number: O22000
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: December 15, 1998
Last modified: October 16, 2013
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families