O22000 (DCTD_BPMD2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidylate deaminase
EC=3.5.4.12

Alternative name(s):
dCMP deaminase

Gene names

Name:	36.1
Synonyms:	G1

Organism

Mycobacterium phage D29 (Mycobacteriophage D29) [Complete proteome]

Taxonomic identifier

28369 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Caudovirales › Siphoviridae › L5likevirus

Virus host

Mycobacterium [TaxID: 1763]

Protein attributes

Sequence length	128 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCMP + H2O = dUMP + NH3.
Sequence similarities	Belongs to the cytidine and deoxycytidylate deaminase family.

Ontologies

Keywords
Biological process	Nucleotide biosynthesis
Ligand	Metal-binding Zinc
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nucleotide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	dCMP deaminase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 128	128	Deoxycytidylate deaminase		PRO_0000171698
Sites
	Active site	83	1	Proton donor By similarity
	Metal binding	81	1	Zinc; catalytic By similarity
	Metal binding	107	1	Zinc; catalytic By similarity
	Metal binding	110	1	Zinc; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	O22000 [UniParc]. Last modified December 15, 1998. Version 2. Checksum: F78F1BA3DB5184D4	FASTA	128	13,539
	10 20 30 40 50 60 MSRPDWDEYF LGIATAAAQR SDCERSKVGA VVVKDRRVRG TGYNGAPAGA AGCSTCPRRL 70 80 90 100 110 120 SGAVPGVSDY SSGATRCVAV HAEANALLYC DREDLIGATL YVTREPCYAC SNLIAASGIE RVVYPKES

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome structure of mycobacteriophage D29: implications for phage evolution." Ford M.E., Sarkis G.J., Belanger A.E., Hendrix R.W., Hatfull G.F. J. Mol. Biol. 279:143-164(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Mycobacteriophage D29 contains an integration system similar to that of the temperate mycobacteriophage L5." Ribeiro G., Viveiros M., David H.L., Costa J.V. Microbiology 143:2701-2708(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 51-128.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF022214 Genomic DNA. Translation: AAC18478.1. U81553 Genomic DNA. Translation: AAB69099.1.
PIR	C72804.
RefSeq	NP_046853.1. NC_001900.1.
3D structure databases
ProteinModelPortal	O22000.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1261565.
Phylogenomic databases
ProtClustDB	CLSP2343399.
Family and domain databases
InterPro	IPR016192. APOBEC/CMP_deaminase_Zn-bd. IPR002125. CMP_dCMP_Zn-bd. IPR015517. Cyt_deaminase. IPR016193. Cytidine_deaminase-like. IPR016473. dCMP_deaminase. [Graphical view]
PANTHER	PTHR11086. PTHR11086. 1 hit.
Pfam	PF00383. dCMP_cyt_deam_1. 1 hit. [Graphical view]
PIRSF	PIRSF006019. dCMP_deaminase. 1 hit.
SUPFAM	SSF53927. Cytidine_deaminase-like. 1 hit.
PROSITE	PS00903. CYT_DCMP_DEAMINASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DCTD_BPMD2

Accession

Primary (citable) accession number: O22000

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	December 15, 1998
Last modified:	May 1, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program