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O21337 (CYB_DASNO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome b
Alternative name(s):
Complex III subunit 3
Complex III subunit III
Cytochrome b-c1 complex subunit 3
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Gene names
Name:MT-CYB
Synonyms:COB, CYTB, MTCYB
Encoded onMitochondrion
OrganismDasypus novemcinctus (Nine-banded armadillo)
Taxonomic identifier9361 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Xenarthra › Cingulata › Dasypodidae › Dasypus

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis By similarity.

Cofactor

Binds 2 heme groups non-covalently By similarity.

Subunit structure

The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1) By similarity.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Miscellaneous

Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm By similarity.

Sequence similarities

Belongs to the cytochrome b family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 379379Cytochrome b
PRO_0000060868

Regions

Transmembrane33 – 5321Helical; Potential
Transmembrane76 – 9621Helical; Potential
Transmembrane115 – 13521Helical; Potential
Transmembrane140 – 15819Helical; Potential
Transmembrane178 – 19821Helical; Potential
Transmembrane229 – 24921Helical; Potential
Transmembrane288 – 30821Helical; Potential
Transmembrane320 – 34021Helical; Potential
Transmembrane348 – 36821Helical; Potential

Sites

Metal binding831Iron 1 (heme b562 axial ligand)
Metal binding971Iron 2 (heme b566 axial ligand)
Metal binding1821Iron 1 (heme b562 axial ligand)
Metal binding1961Iron 2 (heme b566 axial ligand)

Sequences

Sequence LengthMass (Da)Tools
O21337 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 15E73D74C9EFA065

FASTA37942,795
        10         20         30         40         50         60 
MTNIRKNHPL LKIVNQSFID LPTPTSISAW WNFGSLLGIC LAMQILTGLF LAMHYTSDTM 

        70         80         90        100        110        120 
TAFSSVTHIC RDVNYGWLIR YLHANGASLF FMCLYLHIGR GLYYGSYTFL ETWNIGIILL 

       130        140        150        160        170        180 
FTVMATAFMG YVLPWGQMSF WGATVITNLL SAIPYIGTDL VEWIWGGFSV DKATLTRFFA 

       190        200        210        220        230        240 
FHFILPFIIT ALVVVHLLFL HETGSNNPTG ISSNMDTIPF HPYYTIKDIL GLILMILLLM 

       250        260        270        280        290        300 
TLVLFYPDLL GDPDNYTPAN PLNTPPHIKP EWYFLFAYAI LRSIPNKLGG VLALVCSILV 

       310        320        330        340        350        360 
LAIIPLLHTA KQRSLMFRPI SQCLFWLLAA NLMILTWIGG QPVEHPFIII GQVASISYFT 

       370 
IILVLMPIAG LIENKLMKW

« Hide

References

[1]"Phylogenetic analyses of mitochondrial DNA suggest a sister group relationship between Xenarthra (Edentata) and Ferungulates."
Arnason U., Gullberg A., Janke A.
Mol. Biol. Evol. 14:762-768(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Y11832 Genomic DNA. Translation: CAA72519.1.
PIRT11453.
RefSeqNP_007471.1. NC_001821.1.

3D structure databases

ProteinModelPortalO21337.
SMRO21337. Positions 1-379.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID808127.

Organism-specific databases

CTD4519.

Phylogenomic databases

HOVERGENHBG017694.

Family and domain databases

InterProIPR016175. Cyt_b/b6.
IPR005798. Cyt_b/b6_C.
IPR005797. Cyt_b/b6_N.
IPR016174. Di-haem_cyt_TM.
[Graphical view]
PANTHERPTHR19271. PTHR19271. 1 hit.
PfamPF00032. Cytochrom_B_C. 1 hit.
PF13631. Cytochrom_B_N_2. 1 hit.
[Graphical view]
SUPFAMSSF81648. Cytochrome_b/b6_C. 1 hit.
SSF81342. Transmembr_di-haem_cytochrome. 1 hit.
PROSITEPS51003. CYTB_CTER. 1 hit.
PS51002. CYTB_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCYB_DASNO
AccessionPrimary (citable) accession number: O21337
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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