Reviewed, UniProtKB/Swiss-Prot O21272 (NDUS7_RECAM)

Names and origin

Protein names

Recommended name:
    NADH-ubiquinone oxidoreductase 20 kDa subunit
    EC=1.6.5.3
Alternative name(s):
    NADH dehydrogenase subunit 10

Gene names

Name:

NAD10

Encoded on

Mitochondrion

Organism

Reclinomonas americana

Taxonomic identifier

48483 [NCBI]

Taxonomic lineage

Eukaryota › Jakobida › Histionidae › Reclinomonas

Protein attributes

Sequence length	182 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	NADH + ubiquinone = NAD+ + ubiquinol.
Cofactor	Binds 1 4Fe-4S cluster Potential.
Subcellular location	Mitochondrion.
Sequence similarities	Belongs to the complex I 20 kDa subunit family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Mitochondrion
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding NAD
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrion Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: EC iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW quinone binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 182	182	NADH-ubiquinone oxidoreductase 20 kDa subunit		PRO_0000118740
Sites
	Metal binding	57	1	Iron-sulfur (4Fe-4S) Potential
	Metal binding	58	1	Iron-sulfur (4Fe-4S) Potential
	Metal binding	122	1	Iron-sulfur (4Fe-4S) Potential
	Metal binding	152	1	Iron-sulfur (4Fe-4S) Potential

Sequences

	Sequence		Length	Mass (Da)
	O21272-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 0B4663AB65303D48	FASTA	182	20,925
	10 20 30 40 50 60 MEERCFRLGI KTNYKKEIFM ILNNKQNKTE FIVSKMDELV NWARKGSLWP MTFGLACCAV 70 80 90 100 110 120 EMMHSAASRY DLDRFGIIFR PSPRQSDVMI VAGTLTNKMA PALRKVYDQM SEPRWVVSMG 130 140 150 160 170 180 SCANGGGYYH YSYSVVRGCD RIVPVDIYVP GCPPTAEALL YGLLQLQKKI KRSRKTLYWL QK

References

[1]

"An ancestral mitochondrial DNA resembling a eubacterial genome in miniature." Lang B.F., Burger G., O'Kelly C.J., Cedergren R., Golding G.B., Lemieux C., Sankoff D., Turmel M., Gray M.W. Nature 387:493-497(1997) [PubMed: 9168110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 50394.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF007261 Genomic DNA. Translation: AAD11899.1.
PIR	S78166.
RefSeq	NP_044784.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	801085.
Enzyme and pathway databases
BRENDA	1.6.5.3. 307247.
Family and domain databases
InterPro	IPR006137. NADH_UbQ_OxRdtase-like_20kDa. IPR006138. NADH_UbQ_OxRdtase_su-20kDa. IPR014406. NiFe_hyd_3_ssu/Q_oxred_NuoB. [Graphical view]
PANTHER	PTHR11995:SF2. NADH_DH_20kDa. 1 hit. PTHR11995. NiFe_hyd_3_ssu/Q_oxred_NuoB. 1 hit.
Pfam	PF01058. Oxidored_q6. 1 hit. [Graphical view]
TIGRFAMs	TIGR01957. nuoB_fam. 1 hit.
PROSITE	PS01150. COMPLEX1_20K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDUS7_RECAM

Accession

Primary (citable) accession number: O21272

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	June 16, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)