ID NDUS3_RECAM Reviewed; 204 AA. AC O21271; DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot. DT 01-JAN-1998, sequence version 1. DT 16-JUN-2009, entry version 54. DE RecName: Full=NADH-ubiquinone oxidoreductase subunit 9; DE EC=1.6.5.3; DE EC=1.6.99.3; GN Name=NAD9; OS Reclinomonas americana. OG Mitochondrion. OC Eukaryota; Jakobida; Histionidae; Reclinomonas. OX NCBI_TaxID=48483; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 50394; RX MEDLINE=97311393; PubMed=9168110; DOI=10.1038/387493a0; RA Lang B.F., Burger G., O'Kelly C.J., Cedergren R., Golding G.B., RA Lemieux C., Sankoff D., Turmel M., Gray M.W.; RT "An ancestral mitochondrial DNA resembling a eubacterial genome in RT miniature."; RL Nature 387:493-497(1997). CC -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory CC chain NADH dehydrogenase (Complex I) that is believed to belong to CC the minimal assembly required for catalysis. Complex I functions CC in the transfer of electrons from NADH to the respiratory chain. CC The immediate electron acceptor for the enzyme is believed to be CC ubiquinone (By similarity). CC -!- CATALYTIC ACTIVITY: NADH + ubiquinone = NAD(+) + ubiquinol. CC -!- CATALYTIC ACTIVITY: NADH + acceptor = NAD(+) + reduced acceptor. CC -!- SUBUNIT: Complex I is composed of about 30 different subunits. CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane (By CC similarity). Note=Matrix and cytoplasmic side of the mitochondrial CC inner membrane (By similarity). CC -!- SIMILARITY: Belongs to the complex I 30 kDa subunit family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF007261; AAD11898.1; -; Genomic_DNA. DR PIR; S78165; S78165. DR RefSeq; NP_044783.1; -. DR GeneID; 801075; -. DR BRENDA; 1.6.5.3; 307247. DR BRENDA; 1.6.99.3; 307247. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:EC. DR GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. DR GO; GO:0006810; P:transport; IEA:UniProtKB-KW. DR InterPro; IPR010218; NADH_DH_csu. DR InterPro; IPR001268; NADH_UbQ_OxRdtase_30kDa_su. DR Pfam; PF00329; Complex1_30kDa; 1. DR ProDom; PD001581; Complex1_30K; 1. DR TIGRFAMs; TIGR01961; NuoC_fam; 1. DR PROSITE; PS00542; COMPLEX1_30K; 1. PE 3: Inferred from homology; KW Electron transport; Membrane; Mitochondrion; KW Mitochondrion inner membrane; NAD; Oxidoreductase; Respiratory chain; KW Transport; Ubiquinone. FT CHAIN 1 204 NADH-ubiquinone oxidoreductase subunit 9. FT /FTId=PRO_0000118649. SQ SEQUENCE 204 AA; 24239 MW; 8AA999B21913AEC6 CRC64; MKKQEQNQFL KEFGISLIKM FPKYIDKAIY SKGELTLHVK PTNLIALMKI LKNHTNCQFK SLSDLCAVDF PEKKERFEIV YNLLSVRYNS RIRVKTFVDE LTPVPSVTCL FQAAGWFERE VWDLFGVYFT NHPDLRRILT DYGFEGHPMR KDFPLTGYVE VRYDDEQKRV VTESLEMTQE FRSFNFTSPW EQIEISKPNI KEKK //