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O21271

- NDUS3_RECAM

UniProt

O21271 - NDUS3_RECAM

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Protein

NADH-ubiquinone oxidoreductase subunit 9

Gene

NAD9

Organism
Reclinomonas americana
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

  1. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase subunit 9 (EC:1.6.5.3, EC:1.6.99.3)
Gene namesi
Name:NAD9
Encoded oniMitochondrion
OrganismiReclinomonas americana
Taxonomic identifieri48483 [NCBI]
Taxonomic lineageiEukaryotaJakobidaHistionidaeReclinomonas

Subcellular locationi

Mitochondrion inner membrane By similarity
Note: Matrix and cytoplasmic side of the mitochondrial inner membrane.By similarity

GO - Cellular componenti

  1. mitochondrial inner membrane Source: UniProtKB-KW
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204NADH-ubiquinone oxidoreductase subunit 9PRO_0000118649Add
BLAST

Interactioni

Subunit structurei

Complex I is composed of about 30 different subunits.

Structurei

3D structure databases

ProteinModelPortaliO21271.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC.
InterProiIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamiPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01961. NuoC_fam. 1 hit.
PROSITEiPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O21271-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKQEQNQFL KEFGISLIKM FPKYIDKAIY SKGELTLHVK PTNLIALMKI
60 70 80 90 100
LKNHTNCQFK SLSDLCAVDF PEKKERFEIV YNLLSVRYNS RIRVKTFVDE
110 120 130 140 150
LTPVPSVTCL FQAAGWFERE VWDLFGVYFT NHPDLRRILT DYGFEGHPMR
160 170 180 190 200
KDFPLTGYVE VRYDDEQKRV VTESLEMTQE FRSFNFTSPW EQIEISKPNI

KEKK
Length:204
Mass (Da):24,239
Last modified:January 1, 1998 - v1
Checksum:i8AA999B21913AEC6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF007261 Genomic DNA. Translation: AAD11898.1.
PIRiS78165.
RefSeqiNP_044783.1. NC_001823.1.

Genome annotation databases

GeneIDi801075.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF007261 Genomic DNA. Translation: AAD11898.1 .
PIRi S78165.
RefSeqi NP_044783.1. NC_001823.1.

3D structure databases

ProteinModelPortali O21271.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 801075.

Family and domain databases

HAMAPi MF_01357. NDH1_NuoC.
InterProi IPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view ]
Pfami PF00329. Complex1_30kDa. 1 hit.
[Graphical view ]
ProDomi PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
TIGRFAMsi TIGR01961. NuoC_fam. 1 hit.
PROSITEi PS00542. COMPLEX1_30K. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "An ancestral mitochondrial DNA resembling a eubacterial genome in miniature."
    Lang B.F., Burger G., O'Kelly C.J., Cedergren R., Golding G.B., Lemieux C., Sankoff D., Turmel M., Gray M.W.
    Nature 387:493-497(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 50394.

Entry informationi

Entry nameiNDUS3_RECAM
AccessioniPrimary (citable) accession number: O21271
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3