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O21271 (NDUS3_RECAM) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADH-ubiquinone oxidoreductase subunit 9

EC=1.6.5.3
EC=1.6.99.3
Gene names
Name:NAD9
Encoded onMitochondrion
OrganismReclinomonas americana
Taxonomic identifier48483 [NCBI]
Taxonomic lineageEukaryotaJakobidaHistionidaeReclinomonas

Protein attributes

Sequence length204 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. HAMAP-Rule MF_01357

Catalytic activity

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out). HAMAP-Rule MF_01357

NADH + acceptor = NAD+ + reduced acceptor. HAMAP-Rule MF_01357

Subunit structure

Complex I is composed of about 30 different subunits.

Subcellular location

Mitochondrion inner membrane By similarity. Note: Matrix and cytoplasmic side of the mitochondrial inner membrane By similarity. HAMAP-Rule MF_01357

Sequence similarities

Belongs to the complex I 30 kDa subunit family.

Ontologies

Keywords
   Biological processElectron transport
Respiratory chain
Transport
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   LigandNAD
Ubiquinone
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Cellular_componentmitochondrial inner membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

respiratory chain

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionNADH dehydrogenase (ubiquinone) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 204204NADH-ubiquinone oxidoreductase subunit 9 HAMAP-Rule MF_01357
PRO_0000118649

Sequences

Sequence LengthMass (Da)Tools
O21271 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 8AA999B21913AEC6

FASTA20424,239
        10         20         30         40         50         60 
MKKQEQNQFL KEFGISLIKM FPKYIDKAIY SKGELTLHVK PTNLIALMKI LKNHTNCQFK 

        70         80         90        100        110        120 
SLSDLCAVDF PEKKERFEIV YNLLSVRYNS RIRVKTFVDE LTPVPSVTCL FQAAGWFERE 

       130        140        150        160        170        180 
VWDLFGVYFT NHPDLRRILT DYGFEGHPMR KDFPLTGYVE VRYDDEQKRV VTESLEMTQE 

       190        200 
FRSFNFTSPW EQIEISKPNI KEKK 

« Hide

References

[1]"An ancestral mitochondrial DNA resembling a eubacterial genome in miniature."
Lang B.F., Burger G., O'Kelly C.J., Cedergren R., Golding G.B., Lemieux C., Sankoff D., Turmel M., Gray M.W.
Nature 387:493-497(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 50394.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF007261 Genomic DNA. Translation: AAD11898.1.
PIRS78165.
RefSeqNP_044783.1. NC_001823.1.

3D structure databases

ProteinModelPortalO21271.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID801075.

Family and domain databases

HAMAPMF_01357. NDH1_NuoC.
InterProIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR01961. NuoC_fam. 1 hit.
PROSITEPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNDUS3_RECAM
AccessionPrimary (citable) accession number: O21271
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families