Reviewed, UniProtKB/Swiss-Prot O21271 (NDUS3_RECAM)

Names and origin

Protein names

Recommended name:
    NADH-ubiquinone oxidoreductase subunit 9
    EC=1.6.5.3
    EC=1.6.99.3

Gene names

Name:

NAD9

Encoded on

Mitochondrion

Organism

Reclinomonas americana

Taxonomic identifier

48483 [NCBI]

Taxonomic lineage

Eukaryota › Jakobida › Histionidae › Reclinomonas

Protein attributes

Sequence length	204 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.
Catalytic activity	NADH + ubiquinone = NAD+ + ubiquinol. NADH + acceptor = NAD+ + reduced acceptor.
Subunit structure	Complex I is composed of about 30 different subunits.
Subcellular location	Mitochondrion inner membrane By similarity. Note: Matrix and cytoplasmic side of the mitochondrial inner membrane By similarity.
Sequence similarities	Belongs to the complex I 30 kDa subunit family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Ligand	NAD Ubiquinone
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 204	204	NADH-ubiquinone oxidoreductase subunit 9		PRO_0000118649

Sequences

	Sequence		Length	Mass (Da)
	O21271-1 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 8AA999B21913AEC6	FASTA	204	24,239
	10 20 30 40 50 60 MKKQEQNQFL KEFGISLIKM FPKYIDKAIY SKGELTLHVK PTNLIALMKI LKNHTNCQFK 70 80 90 100 110 120 SLSDLCAVDF PEKKERFEIV YNLLSVRYNS RIRVKTFVDE LTPVPSVTCL FQAAGWFERE 130 140 150 160 170 180 VWDLFGVYFT NHPDLRRILT DYGFEGHPMR KDFPLTGYVE VRYDDEQKRV VTESLEMTQE 190 200 FRSFNFTSPW EQIEISKPNI KEKK

References

[1]

"An ancestral mitochondrial DNA resembling a eubacterial genome in miniature." Lang B.F., Burger G., O'Kelly C.J., Cedergren R., Golding G.B., Lemieux C., Sankoff D., Turmel M., Gray M.W. Nature 387:493-497(1997) [PubMed: 9168110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 50394.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF007261 Genomic DNA. Translation: AAD11898.1.
PIR	S78165.
RefSeq	NP_044783.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	801075.
Enzyme and pathway databases
BRENDA	1.6.5.3. 307247. 1.6.99.3. 307247.
Family and domain databases
InterPro	IPR010218. NADH_DH_csu. IPR001268. NADH_UbQ_OxRdtase_30kDa_su. [Graphical view]
Pfam	PF00329. Complex1_30kDa. 1 hit. [Graphical view]
ProDom	PD001581. Complex1_30K. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01961. NuoC_fam. 1 hit.
PROSITE	PS00542. COMPLEX1_30K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDUS3_RECAM

Accession

Primary (citable) accession number: O21271

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	January 1, 1998
Last modified:	June 16, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)