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Protein

Cytochrome c oxidase subunit 3

Gene

cox3

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:cox3
ORF Names:DDB_G0294092
Encoded oniMitochondrion
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componenti: Mitochondrion

Organism-specific databases

dictyBaseiDDB_G0294092 cox3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei96 – 116HelicalSequence analysisAdd BLAST21
Transmembranei132 – 152HelicalSequence analysisAdd BLAST21
Transmembranei176 – 196HelicalSequence analysisAdd BLAST21
Transmembranei325 – 345HelicalSequence analysisAdd BLAST21
Transmembranei360 – 380HelicalSequence analysisAdd BLAST21
Transmembranei412 – 432HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003123701 – 435Cytochrome c oxidase subunit 3Add BLAST435

Proteomic databases

PRIDEiO21049

Structurei

3D structure databases

ProteinModelPortaliO21049
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiO21049
KOiK02262
PhylomeDBiO21049

Family and domain databases

CDDicd01665 Cyt_c_Oxidase_III, 1 hit
Gene3Di1.20.120.80, 2 hits
InterProiView protein in InterPro
IPR024791 Cyt_c/ubiquinol_Oxase_su3
IPR033945 Cyt_c_oxase_su3_dom
IPR000298 Cyt_c_oxidase-like_su3
IPR035973 Cyt_c_oxidase_su3-like_sf
IPR013833 Cyt_c_oxidase_su3_a-hlx
PANTHERiPTHR11403 PTHR11403, 1 hit
PfamiView protein in Pfam
PF00510 COX3, 2 hits
SUPFAMiSSF81452 SSF81452, 2 hits
PROSITEiView protein in PROSITE
PS50253 COX3, 1 hit

Sequencei

Sequence statusi: Complete.

O21049-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGFFENLFR QNVRSVINTG KKVGARAAAR EIINQEWGYP LANHEVLFLT
60 70 80 90 100
NVYQPKHMKR HPFHIVRGTV APLAVTLPLG FFVLNYFGVI SSKLGLLIAL
110 120 130 140 150
SSFIGGLVIW TISIIFDSLY DQQHTYEVKR GLVMGMMMFI ISEVMFFFSF
160 170 180 190 200
FWSYFYISLS PNIAIGCVWP PYGLTVYSYM GLPLLNTVLL LLSGAILTDG
210 220 230 240 250
YTILTEQKAV HEKNEKVLAV EEAFKNLMNL YKTKNSINTL TFVDERRDKF
260 270 280 290 300
FGKESRQEDK IAEQKLIAIS AGVKELRDLD WDLYFFENPE NIEPNYKEPT
310 320 330 340 350
NLSVIEYALI TIYLKKRNKV IKTRLYFTLL CAVVFLACQG YEYFFAPFSM
360 370 380 390 400
NDGIYGSLFF LLTGFHGFHV LVGSILIGII TIRFIVGNFN LLNVGTNFQI
410 420 430
YKNKSTGFAC TLFYWHFVDI VWIFLYIVIY WWGSR
Length:435
Mass (Da):50,234
Last modified:January 1, 1998 - v1
Checksum:i5AC920869B67F434
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D16579 Genomic DNA Translation: BAA21120.1
AB000109 Genomic DNA Translation: BAA78053.1
PIRiT43749
RefSeqiNP_050071.1, NC_000895.1

Genome annotation databases

GeneIDi2193893
KEGGiddi:DidioMp04

Similar proteinsi

Entry informationi

Entry nameiCOX3_DICDI
AccessioniPrimary (citable) accession number: O21049
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families
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