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O19998 (HO_RHOVL) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Heme oxygenase

EC=1.14.99.3
Gene names
Name:pbsA
Encoded onPlastid; Chloroplast
OrganismRhodella violacea (Red alga)
Taxonomic identifier2801 [NCBI]
Taxonomic lineageEukaryotaRhodophytaRhodellophyceaeRhodellalesRhodellaceaeRhodella

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae.

Catalytic activity

Protoheme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O.

Subcellular location

Plastidchloroplast.

Sequence similarities

Belongs to the heme oxygenase family.

Ontologies

Keywords
   Biological processPhotosynthesis
   Cellular componentChloroplast
Plastid
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processheme oxidation

Inferred from electronic annotation. Source: InterPro

photosynthesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionheme oxygenase (decyclizing) activity

Inferred from electronic annotation. Source: UniProtKB-EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 235235Heme oxygenase
PRO_0000209700

Sites

Metal binding191Iron (heme axial ligand) By similarity

Sequences

Sequence LengthMass (Da)Tools
O19998 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: F0E797F8D5B72845

FASTA23527,144
        10         20         30         40         50         60 
MIYDTNLALQ LRQGTTKAHS MAENVSFVKS FLGGVVDKQA YRQLIANFYF VYSAIEDEMK 

        70         80         90        100        110        120 
RHQESQIIKP IYFEELNRKS SLEEDLQFYY GLEWQDKIFP SPATKVYINR IHEISNTSPE 

       130        140        150        160        170        180 
LLIAHCYTRY LGDLSGGQIL KKITQSAMNL SGGEGTAFYE FKDIKDEKNF KQNYRLALDS 

       190        200        210        220        230 
IHLSDSAIKS IVSEANIAFK LNMKIFQELN SNFIKIIAIF LFNFIKRIKL PGFKS 

« Hide

References

[1]"The heme oxygenase gene (pbsA) in the red alga Rhodella violacea is discontinuous and transcriptionally activated during iron limitation."
Richaud C., Zabulon G.
Proc. Natl. Acad. Sci. U.S.A. 94:11736-11741(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF000719, AF000717, AF000718 Genomic DNA. Translation: AAB66516.1.

3D structure databases

ProteinModelPortalO19998.
SMRO19998. Positions 5-225.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.910.10. 1 hit.
InterProIPR002051. Haem_Oase.
IPR016053. Haem_Oase-like.
IPR016084. Haem_Oase-like_multi-hlx.
IPR018207. Haem_oxygenase_CS.
[Graphical view]
PANTHERPTHR10720. PTHR10720. 1 hit.
PfamPF01126. Heme_oxygenase. 1 hit.
[Graphical view]
PIRSFPIRSF000343. Haem_Oase. 1 hit.
PRINTSPR00088. HAEMOXYGNASE.
SUPFAMSSF48613. SSF48613. 1 hit.
PROSITEPS00593. HEME_OXYGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHO_RHOVL
AccessionPrimary (citable) accession number: O19998
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: October 16, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families