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O19908

- GLMS_CYACA

UniProt

O19908 - GLMS_CYACA

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Cyanidium caldarium
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

    Catalytic activityi

    L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei2 – 21Nucleophile; for GATase activityUniRule annotation
    Active sitei616 – 6161For Fru-6P isomerization activityUniRule annotation

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbohydrate biosynthetic process Source: InterPro
    2. glutamine metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminotransferase, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
    Alternative name(s):
    D-fructose-6-phosphate amidotransferaseUniRule annotation
    GFATUniRule annotation
    Glucosamine-6-phosphate synthaseUniRule annotation
    Hexosephosphate aminotransferaseUniRule annotation
    L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
    Gene namesi
    Name:glmSUniRule annotation
    Synonyms:gcaA
    Encoded oniPlastid; Chloroplast
    OrganismiCyanidium caldarium
    Taxonomic identifieri2771 [NCBI]
    Taxonomic lineageiEukaryotaRhodophytaBangiophyceaeCyanidialesCyanidiaceaeCyanidium

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Chloroplast, Plastid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedUniRule annotation
    Chaini2 – 621620Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135421Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliO19908.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 223222Glutamine amidotransferase type-2UniRule annotationAdd
    BLAST
    Domaini289 – 436148SIS 1UniRule annotationAdd
    BLAST
    Domaini470 – 611142SIS 2UniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 glutamine amidotransferase type-2 domain.UniRule annotation
    Contains 2 SIS domains.UniRule annotation

    Keywords - Domaini

    Glutamine amidotransferase, Repeat

    Family and domain databases

    Gene3Di3.60.20.10. 1 hit.
    HAMAPiMF_00164. GlmS.
    InterProiIPR017932. GATase_2_dom.
    IPR005855. GlmS_trans.
    IPR029055. Ntn_hydrolases_N.
    IPR001347. SIS.
    [Graphical view]
    PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
    PfamiPF01380. SIS. 2 hits.
    [Graphical view]
    SUPFAMiSSF56235. SSF56235. 1 hit.
    TIGRFAMsiTIGR01135. glmS. 1 hit.
    PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
    PS51464. SIS. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O19908-1 [UniParc]FASTAAdd to Basket

    « Hide

    MCGIIGYVGE GSCRDVLING LDKLSYRGYD SAGIAFIKNS KINVVRSKGR    50
    IEKLKEKIND NFQKFEIGNI GIGHTRWATH GEPTEINAHP HLDAEGQFAV 100
    VQNGVIENYV QLKNYLTVNG TYFLSDTDAE VIPHLIAYKQ KHLKLQIVEA 150
    ILCALSELKG NFSTVIIARD MPDSIFVYQN KTALTLGKGS NFYSVSSDPI 200
    ALIPYTKNFI QLHDRELGII SISQLAIYNK GKFTYPSRRF KANLNDLITN 250
    KASFDSYTLK EIHDQKKVLR NLIISTLQSE KSIDESGQLH LEYKKIKNFQ 300
    IIACGSSFNA ALVGKVILEK LIRIPVHVYY GSEFKTNLPP LLPCTLTIAV 350
    SQSGETGDML SAIEIEKSRR KFQNTVYKPY LLSITNKNYS SITKKTAQSI 400
    DLKAGIEIGV AATKTFTAQT LSFYLLALKL AEHKFTLRKK EINKHLDEIR 450
    NLPKAIAHLL IKDESSIKWL SKQLKEISKC FYIGKGLNLG SALEGALKLK 500
    EISYIHCDGY AAGEIKHGPI ALVENNTLII TITDPEQSQE STFASSQEAK 550
    ARGAVLLAIT HIEDSSIYQT FDFIIKIPKI SQICASITSS VSLQLFAYYM 600
    AYYKGNDIDK PRNLAKSVTV E 621
    Length:621
    Mass (Da):69,302
    Last modified:January 23, 2007 - v3
    Checksum:i64718F4EBB9E8B69
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF022186 Genomic DNA. Translation: AAB82681.1.
    PIRiT11976.
    RefSeqiNP_045080.1. NC_001840.1.

    Genome annotation databases

    GeneIDi800239.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF022186 Genomic DNA. Translation: AAB82681.1 .
    PIRi T11976.
    RefSeqi NP_045080.1. NC_001840.1.

    3D structure databases

    ProteinModelPortali O19908.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 800239.

    Family and domain databases

    Gene3Di 3.60.20.10. 1 hit.
    HAMAPi MF_00164. GlmS.
    InterProi IPR017932. GATase_2_dom.
    IPR005855. GlmS_trans.
    IPR029055. Ntn_hydrolases_N.
    IPR001347. SIS.
    [Graphical view ]
    PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
    Pfami PF01380. SIS. 2 hits.
    [Graphical view ]
    SUPFAMi SSF56235. SSF56235. 1 hit.
    TIGRFAMsi TIGR01135. glmS. 1 hit.
    PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
    PS51464. SIS. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The structure and gene repertoire of an ancient red algal plastid genome."
      Gloeckner G., Rosenthal A., Valentin K.-U.
      J. Mol. Evol. 51:382-390(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RK-1.

    Entry informationi

    Entry nameiGLMS_CYACA
    AccessioniPrimary (citable) accession number: O19908
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 20, 2001
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 73 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3