O19721 (O19721_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: MHC class II HLA-DR-beta chain EMBL AAA36286.1
Organism	Homo sapiens (Human) EMBL AAA36286.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	50 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Signal EMBL AAA36286.1
Gene Ontology (GO)
Biological_process	antigen processing and presentation Inferred from electronic annotation. Source: InterPro immune response Inferred from electronic annotation. Source: InterPro
Cellular_component	MHC class II protein complex Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 29	29	Potential EMBL AAA36286.1
	Chain	30 – ›50	›21	Potential EMBL AAA36286.1		PRO_5000143296
Experimental info
	Non-terminal residue	50	1	EMBL AAA36286.1

Sequences

	Sequence		Length	Mass (Da)
	O19721 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 8E329CDD5EF68CE9	FASTA	50	5,394
	10 20 30 40 50 MVCLRLPGGS CMAVLTVTLM VLSSPLALAG DTRPRFLEYS TSECHFFNGT

References

[1]	"Signal sequences distinguish class II histocompatibility antigen beta chains of different loci." Gustafsson K., Wiman K., Larhammar D., Rask L., Peterson P.A. Scand. J. Immunol. 19:91-97(1984) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M35980 mRNA. Translation: AAA36286.1.
IPI	IPI00473139.
PIR	I80356.
3D structure databases
ProteinModelPortal	O19721.
ModBase	Search...
Proteomic databases
PRIDE	O19721.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	O19721.
Family and domain databases
Gene3D	3.10.320.10. 1 hit.
InterPro	IPR014745. MHC_II_a/b_N. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O19721_HUMAN

Accession

Primary (citable) accession number: O19721

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	May 29, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.