Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O19696

- O19696_HUMAN

UniProt

O19696 - O19696_HUMAN

Protein
Submitted name:

Major histocompatibility complex class II

Gene

HLA-DRB1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Biological processi

    1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
    2. immune response Source: InterPro

    Keywords - Biological processi

    Immunity

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Major histocompatibility complex class IIImported
    Gene namesi
    Name:HLA-DRB1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. MHC class II protein complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, MHC IIUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiO19696.

    Structurei

    3D structure databases

    ProteinModelPortaliO19696.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    TransmembraneUniRule annotation

    Family and domain databases

    Gene3Di3.10.320.10. 1 hit.
    InterProiIPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view]
    PfamiPF00969. MHC_II_beta. 1 hit.
    [Graphical view]
    ProDomiPD000328. MHC_II_b_N. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00921. MHC_II_beta. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    O19696-1 [UniParc]FASTAAdd to Basket

    « Hide

    SECHFFNGTE RVRYLDRYFH NQEENVRFDS DVGEFRAVTE LGRPDAEYWN   50
    SQKDLLEQKR GRVDNYCRHN YGVV 74
    Length:74
    Mass (Da):8,963
    Last modified:January 1, 1998 - v1
    Checksum:i424D614D23B30FAA
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei74 – 741Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L07767 Genomic DNA. Translation: AAA59689.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L07767 Genomic DNA. Translation: AAA59689.1 .

    3D structure databases

    ProteinModelPortali O19696.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi O19696.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    ChiTaRSi HLA-DRB1. human.

    Family and domain databases

    Gene3Di 3.10.320.10. 1 hit.
    InterProi IPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view ]
    Pfami PF00969. MHC_II_beta. 1 hit.
    [Graphical view ]
    ProDomi PD000328. MHC_II_b_N. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00921. MHC_II_beta. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Identification of new class II HLA DRB1, DRB4 and DPB1 alleles in the Belgian population."
      Buyse I., Marynen P., Cassiman J.J.
      Submitted (DEC-1992) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LeukocyteImported.

    Entry informationi

    Entry nameiO19696_HUMAN
    AccessioniPrimary (citable) accession number: O19696
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 1, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.