O19660 (O19660_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: HLA-DRB1*03.01 class II antigen beta I (DR3) EMBL CAA27687.1
Organism	Homo sapiens (Human) EMBL CAA27687.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	89 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Immunity
Cellular component	MHC II RuleBase RU000321 Membrane
Domain	Transmembrane RuleBase RU000321
Gene Ontology (GO)
Biological_process	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Inferred from electronic annotation. Source: UniProtKB-KW immune response Inferred from electronic annotation. Source: InterPro
Cellular_component	MHC class II protein complex Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAA27687.1
	Non-terminal residue	89	1	EMBL CAA27687.1

Sequences

	Sequence		Length	Mass (Da)
	O19660 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 3ECCE64964BA134B	FASTA	89	10,864
	10 20 30 40 50 60 RFLEYSTSEC HFFNGTERVR YLDRYFHNQE ENVRFDSDVG EFRAVTELGR PDAEYWNSQK 70 80 DLLEQKRGRV DNYCRHNYGV VESFTVQRR

References

[1]	"Polymorphism of human Ia antigens: gene conversion between two DR beta loci results in a new HLA-D/DR specificity." Gorski J., Mach B. Nature 322:67-70(1986) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X04054 Genomic DNA. Translation: CAA27687.1.
IPI	IPI00956491.
PIR	I68554.
3D structure databases
HSSP	HSSP built from PDB template 1A6A based on UniProtKB P01912.
ProteinModelPortal	O19660.
ModBase	Search...
Protein-protein interaction databases
STRING	O19660.
Proteomic databases
PRIDE	O19660.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	O19660.
Family and domain databases
Gene3D	3.10.320.10. 1 hit.
InterPro	IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N. [Graphical view]
Pfam	PF00969. MHC_II_beta. 1 hit. [Graphical view]
ProDom	PD000328. MHC_II_b_N. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00921. MHC_II_beta. 1 hit. [Graphical view]
SUPFAM	SSF54452. MHC_I/II-like_Ag-recog. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O19660_HUMAN

Accession

Primary (citable) accession number: O19660

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.