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O19470 (O19470_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:H2-Ab1 MGI 103070
OrganismMus musculus (Mouse) EMBL AAA39637.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length231 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS014745

Ontologies

Keywords
   Biological processImmunity
   Cellular componentMembrane
MHC II SAAS SAAS014745 RuleBase RU000321
   DomainTransmembrane
Transmembrane helix SAAS SAAS014745
Gene Ontology (GO)
   Biological_processantigen processing and presentation

Inferred from direct assay PubMed 9432982. Source: MGI

antigen processing and presentation of exogenous peptide antigen via MHC class II

Inferred from direct assay PubMed 11027433PubMed 11069069PubMed 11714799PubMed 7679955PubMed 8598040PubMed 8598041PubMed 9432982PubMed 9492004. Source: MGI

antigen processing and presentation of peptide antigen

Inferred from direct assay PubMed 11069069. Source: MGI

immune response

Inferred from mutant phenotype PubMed 1909605. Source: MGI

   Cellular_componentGolgi apparatus

Inferred from direct assay PubMed 7679955. Source: MGI

MHC class II protein complex

Inferred from direct assay PubMed 11148202PubMed 7679955PubMed 7985028PubMed 8598040PubMed 8598041PubMed 8638109PubMed 9432982PubMed 9492004. Source: MGI

early endosome

Inferred from direct assay PubMed 11854359. Source: MGI

external side of plasma membrane

Inferred from direct assay PubMed 11148202PubMed 12801066PubMed 14643301PubMed 7679955PubMed 8598040PubMed 8598041PubMed 8638109PubMed 9432982PubMed 9492004. Source: MGI

integral component of membrane

Inferred from direct assay PubMed 7584146. Source: MGI

intracellular

Inferred from direct assay PubMed 8890155. Source: MGI

multivesicular body

Inferred from direct assay PubMed 11854359. Source: MGI

plasma membrane

Inferred from direct assay PubMed 11854359PubMed 7679955PubMed 7985028PubMed 8638109PubMed 8890155. Source: MGI

   Molecular_functionpeptide antigen binding

Inferred from direct assay PubMed 11069069PubMed 9432982. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAA39637.1

Sequences

Sequence LengthMass (Da)Tools
O19470 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 26769976A04076E7

FASTA23126,748
        10         20         30         40         50         60 
HFVHQFQPFC YFTNGTQRIR LVIRYIYNRE EYVRFDSDVG EYRAVTELGR PDAEYWNKQY 

        70         80         90        100        110        120 
LERTRAELDT VCRHNYEKTE TPTSLRRLEQ PSVVISLSRT EALNHHNTLV CSVTDFYPAK 

       130        140        150        160        170        180 
IKVRWFRNGQ EETVGVSSTQ LIRNGDWTFQ VLVMLEMTPR RGEVYTCHVE HPSLKSPITV 

       190        200        210        220        230 
EWRAQSESAR SKMLSGIGGC VLGVIFLGLG LFIRHRSQKG PRGPPPAGLL Q 

« Hide

References

[1]"Signaling to a B-cell clone by Ek, but not Ak, does not reflect alteration of Ak genes."
Bishop G.A., McMillan M.S., Haughton G., Frelinger J.A.
Immunogenetics 28:184-192(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M21932 mRNA. Translation: AAA39637.1.
UniGeneMm.254067.

3D structure databases

ProteinModelPortalO19470.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:103070. H2-Ab1.

Phylogenomic databases

HOVERGENHBG012730.
InParanoidO19470.

Gene expression databases

GenevestigatorO19470.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamPF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMSSF54452. SSF54452. 1 hit.
PROSITEPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameO19470_MOUSE
AccessionPrimary (citable) accession number: O19470
Entry history
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)