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O19470

- O19470_MOUSE

UniProt

O19470 - O19470_MOUSE

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Protein
Submitted name: MHC class II H2-I-A-beta gene (k haplotype), 3' end.
Gene
H2-Ab1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. peptide antigen binding Source: MGI
  2. protein binding Source: MGI
Complete GO annotation...

GO - Biological processi

  1. antigen processing and presentation Source: MGI
  2. antigen processing and presentation of exogenous peptide antigen via MHC class II Source: MGI
  3. antigen processing and presentation of peptide antigen Source: MGI
  4. immune response Source: MGI
Complete GO annotation...

Keywords - Biological processi

Immunity

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class II H2-I-A-beta gene (k haplotype), 3' end.Imported
Gene namesi
Name:H2-Ab1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:103070. H2-Ab1.

Subcellular locationi

GO - Cellular componenti

  1. Golgi apparatus Source: MGI
  2. MHC class II protein complex Source: MGI
  3. early endosome Source: MGI
  4. external side of plasma membrane Source: MGI
  5. integral component of membrane Source: MGI
  6. intracellular Source: MGI
  7. multivesicular body Source: MGI
  8. plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MHC IIUniRule annotationSAAS annotations

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

GenevestigatoriO19470.

Structurei

3D structure databases

ProteinModelPortaliO19470.

Family & Domainsi

Sequence similaritiesi

Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG012730.
InParanoidiO19470.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomiPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

O19470-1 [UniParc]FASTAAdd to Basket

« Hide

HFVHQFQPFC YFTNGTQRIR LVIRYIYNRE EYVRFDSDVG EYRAVTELGR    50
PDAEYWNKQY LERTRAELDT VCRHNYEKTE TPTSLRRLEQ PSVVISLSRT 100
EALNHHNTLV CSVTDFYPAK IKVRWFRNGQ EETVGVSSTQ LIRNGDWTFQ 150
VLVMLEMTPR RGEVYTCHVE HPSLKSPITV EWRAQSESAR SKMLSGIGGC 200
VLGVIFLGLG LFIRHRSQKG PRGPPPAGLL Q 231
Length:231
Mass (Da):26,748
Last modified:January 1, 1998 - v1
Checksum:i26769976A04076E7
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M21932 mRNA. Translation: AAA39637.1.
UniGeneiMm.254067.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M21932 mRNA. Translation: AAA39637.1 .
UniGenei Mm.254067.

3D structure databases

ProteinModelPortali O19470.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:103070. H2-Ab1.

Phylogenomic databases

HOVERGENi HBG012730.
InParanoidi O19470.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Genevestigatori O19470.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view ]
ProDomi PD000328. MHC_II_b_N. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Signaling to a B-cell clone by Ek, but not Ak, does not reflect alteration of Ak genes."
    Bishop G.A., McMillan M.S., Haughton G., Frelinger J.A.
    Immunogenetics 28:184-192(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO19470_MOUSE
AccessioniPrimary (citable) accession number: O19470
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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