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O19190

- O19190_HUMAN

UniProt

O19190 - O19190_HUMAN

Protein
Submitted name:

MHC class II HLA-DR-beta

Gene

HLA-DRB1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Biological processi

    1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
    2. immune response Source: InterPro

    Keywords - Biological processi

    Immunity

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MHC class II HLA-DR-betaImported
    Gene namesi
    Name:HLA-DRB1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. MHC class II protein complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, MHC IIUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiO19190.

    Structurei

    3D structure databases

    ProteinModelPortaliO19190.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    HOVERGENiHBG012730.

    Family and domain databases

    Gene3Di3.10.320.10. 1 hit.
    InterProiIPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view]
    PfamiPF00969. MHC_II_beta. 1 hit.
    [Graphical view]
    ProDomiPD000328. MHC_II_b_N. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00921. MHC_II_beta. 1 hit.
    [Graphical view]
    SUPFAMiSSF54452. SSF54452. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    O19190-1 [UniParc]FASTAAdd to Basket

    « Hide

    GDTRPRFLEY STSECHFFNG TERVRYLDRY FHNQEENVRF DSDVGEFRAV    50
    TELGRPDAEY WNSQKDLLEQ KRGRVDNYCR HNYGVVESFT VQRRVHPKVT 100
    VY 102
    Length:102
    Mass (Da):12,315
    Last modified:January 1, 1998 - v1
    Checksum:i35081A8721E4542C
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei102 – 1021Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U35729 mRNA. Translation: AAA79144.1.
    UniGeneiHs.534322.
    Hs.696211.
    Hs.716081.
    Hs.723344.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U35729 mRNA. Translation: AAA79144.1 .
    UniGenei Hs.534322.
    Hs.696211.
    Hs.716081.
    Hs.723344.

    3D structure databases

    ProteinModelPortali O19190.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi O19190.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG012730.

    Miscellaneous databases

    ChiTaRSi HLA-DRB1. human.

    Family and domain databases

    Gene3Di 3.10.320.10. 1 hit.
    InterProi IPR011162. MHC_I/II-like_Ag-recog.
    IPR014745. MHC_II_a/b_N.
    IPR000353. MHC_II_b_N.
    [Graphical view ]
    Pfami PF00969. MHC_II_beta. 1 hit.
    [Graphical view ]
    ProDomi PD000328. MHC_II_b_N. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00921. MHC_II_beta. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54452. SSF54452. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Hurley C.K.
      Submitted (SEP-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BloodImported.

    Entry informationi

    Entry nameiO19190_HUMAN
    AccessioniPrimary (citable) accession number: O19190
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 1, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.