O18887 (O18887_PIG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
K-Cl cotransporter EMBL AAB84137.1

Submitted name:
Solute carrier family 12 (Potassium/chloride transporters), member 4 tv1 EMBL JAA74176.1

Gene names

Name:

SLC12A4 EMBL JAA74176.1

Organism

Sus scrofa (Pig) EMBL AAB84137.1

Taxonomic identifier

9823 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Suina › Suidae › Sus

Protein attributes

Sequence length	1086 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	potassium:chloride symporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O18887 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: B81A8A22BB9F4325	FASTA	1,086	120,788
	10 20 30 40 50 60 MPHFTVVPVD GPRRGDYDNL EGLSWVDYGE RADREDSDGH GNQKESSPFL CPMEASRGND 70 80 90 100 110 120 YCDRNLALFE EELDIRPKVS SLLGKLVSYT NLTQGAKEHE EAESGEGTRR RAAKAPSMGT 130 140 150 160 170 180 LMGVYLPCLQ NIFGVILFLR LTWMVGTAGV LQALLIVLIC CCCTLLTAIS MSAIATNGVV 190 200 210 220 230 240 PAGGSYFMIS RSLGPEFGGA VGLCFYLGTT FAAAMYILGA IEILLTYIAP PAAIFYPTGT 250 260 270 280 290 300 HDTSSATLNN MRVYGTIFLT FMTLVVFVGV KYVNKFASLF LACVIISILS IYAGGIKSIF 310 320 330 340 350 360 DPPVFPVCML GNRTLSRDQF DVCAKTVMVD NETVTTRLWS LFCHSPNLTA DSCDPYFLLN 370 380 390 400 410 420 NVTEIPGIPG AAASVLQENL WSAYLEKGEV VEKHGLPSTD ALGLKESLPL YVVADIATSF 430 440 450 460 470 480 TVLVGIFFPS VTGIMAGSNR SGDLRDAQKS IPVGTILAII TTSLVYFSSV VLFGACIEGV 490 500 510 520 530 540 VLRDKYGDGV SRNLVVGTLA WPSPWVIVIG SFFSTCGAGL QSLTGAPRLL QAIAKDNIIP 550 560 570 580 590 600 FLRVFGHGKA NGEPTWALLL TALIAELGIL IASLDMVAPI LSMFFLMCYL FVNLACAVQT 610 620 630 640 650 660 LLRTPNWRPR FKYYHWALSF LGMSLCLALM FVSSWYYALV AMLIAGMIYK YIEYQGAEKE 670 680 690 700 710 720 WGDGIRGLSL SAARYALLRL EEGPPHTKNW RPQLLVLLKL DEDLHVKYPR LLTFASQLKA 730 740 750 760 770 780 GKGLTIVGSV IQGSFLESYG EAQAAEQTIK NMMEIEKVKG FCQVVVASKV REGLAHLIQS 790 800 810 820 830 840 CGLGGMRHNS VVLGWPYGWR QSEDPRAWKT FIDTVRCTTA AHLALLVPKN IAFYPSNHER 850 860 870 880 890 900 YLEGHIDVWW IVHDGGMLML LPFLLRQHKV WRKCRMRIFT VAQMDDNSIQ MKKDLAIFLY 910 920 930 940 950 960 HLRLEAEVEV VEMPNSDISA YTYERTLMME QRSQMLRQMR LTKTEREREA QLVKDRHSAL 970 980 990 1000 1010 1020 RLESLYSDEE DESVAGTDKI QMTWTRDKYM EAEPWDPSHT PDNFRELVHI KPDQSNVRRM 1030 1040 1050 1060 1070 1080 HTAVKLNEVI VTRSHDARLV LLNMPGPPKN SEGDENYMEF LEVLTEGLER VLLVRGGGRE VITIYS

References

[1]	Holtzman E.J. Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Cloning and Characterization of the K-Cl Cotransporter (KCC1) from LLC-PK1 Cells and Human Kidney." Holtzman E.J., Kumar S., Kumar S., Warner F., Logue P., Faaland C.A., Ricken G., Waldman J., Dunham P.B. Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Global Gene Expression Profiling of Alveolar Macrophages by Deep Sequencing." Dawson H.D., Chen C.T. Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF028807 mRNA. Translation: AAB84137.1. GACC01000408 mRNA. Translation: JAA74176.1.
PIR	T14114.
RefSeq	NP_999114.1. NM_213949.1.
UniGene	Ssc.4097.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	396992.
KEGG	ssc:396992.
Organism-specific databases
CTD	6560.
Phylogenomic databases
HOVERGEN	HBG052852.
KO	K14427.
Family and domain databases
InterPro	IPR004841. AA-permease_dom. IPR000622. K/Cl_cotranspt1. IPR018491. K/Cl_cotranspt_1/3. IPR000076. KCL_cotranspt. IPR004842. Na/K/Cl_cotransptS. [Graphical view]
Pfam	PF00324. AA_permease. 2 hits. PF03522. KCl_Cotrans_1. 1 hit. [Graphical view]
PRINTS	PR01081. KCLTRNSPORT. PR01082. KCLTRNSPORT1.
TIGRFAMs	TIGR00930. 2a30. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O18887_PIG

Accession

Primary (citable) accession number: O18887

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)