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Protein
Submitted name:

Cysteine protease

Gene

ldccys2

Organism
Leishmania chagasi
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Protein family/group databases

MEROPSiC01.076.

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteine proteaseImported
Gene namesi
Name:ldccys2Imported
OrganismiLeishmania chagasiImported
Taxonomic identifieri44271 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeLeishmaniinaeLeishmania

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23UniRule annotationAdd BLAST23
ChainiPRO_500539989624 – 353UniRule annotationAdd BLAST330

Structurei

3D structure databases

ProteinModelPortaliO18699.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 98Inhibitor_I29InterPro annotationAdd BLAST58
Domaini128 – 339Pept_C1InterPro annotationAdd BLAST212

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR025661. Pept_asp_AS.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
IPR013201. Prot_inhib_I29.
PANTHERiPTHR12411. PTHR12411. 1 hit.
PfamiView protein in Pfam
PF08246. Inhibitor_I29. 1 hit.
PF00112. Peptidase_C1. 1 hit.
PRINTSiPR00705. PAPAIN.
SMARTiView protein in SMART
SM00848. Inhibitor_I29. 1 hit.
SM00645. Pept_C1. 1 hit.
PROSITEiView protein in PROSITE
PS00640. THIOL_PROTEASE_ASN. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.

Sequencei

Sequence statusi: Complete.

O18699-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARNPFFFAI VVTILFVVCY GSALIAQTPL GVDDFIASAH YGRFKKRHGK
60 70 80 90 100
PFGEDAEEGR RFNAFKQNMQ TAYFLNAHNP HAHYDVSGKF ADLTPQEFAK
110 120 130 140 150
LYLNPNYYAR HGKDYKEHVH VDDSVRSGVM SVDWREKGVV TPVKNQGMCG
160 170 180 190 200
SCWAFATTGN IEGQWALKNH SLVSLSEQVL VSCDNIDDGC NGGLMQQAMQ
210 220 230 240 250
WIINDHNGTV PTEDSYPYTS AGGTRPPCHD NGTVGAKIAG YMSLPHDEEE
260 270 280 290 300
IAAYVGKNGP VAVAVDATTW QLYFGGVVTL CFGLSLNHGV LVVGFNRQAK
310 320 330 340 350
PPYWIVKNSW GSSWGEKGYI RLAMGSNQCL LKNYAVTATI DDSNTSHVPT

TAA
Length:353
Mass (Da):38,746
Last modified:October 1, 2001 - v2
Checksum:iD6C931C689300FB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF004593 Genomic DNA. Translation: AAC38833.2.

Similar proteinsi

Entry informationi

Entry nameiO18699_LEICH
AccessioniPrimary (citable) accession number: O18699
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: October 1, 2001
Last modified: October 25, 2017
This is version 72 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)