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Protein

PBAN-type neuropeptides

Gene

PBAN

Organism
Helicoverpa assulta (Oriental tobacco budworm) (Heliothis assulta)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity).1 Publication

Miscellaneous

Juvenile hormone seems to allow PBAN release, which then induces pheromone biosynthesis.By similarity
PBAN is produced independent of the photoperiod. The circadian rhythm in pheromone production is due to the circadian rhythm of PBAN release.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHormone, Neuropeptide
Biological processPheromone response

Names & Taxonomyi

Protein namesi
Recommended name:
PBAN-type neuropeptides
Alternative name(s):
Pheromone/pyrokinin biosynthesis-activating neuropeptide
Cleaved into the following 5 chains:
Alternative name(s):
Pyrokinin-1
Alternative name(s):
Pyrokinin-2
Pheromone biosynthesis-activating neuropeptide
Short name:
Has-PBAN
Short name:
HeA-PBAN
Alternative name(s):
Pyrokinin-3
Alternative name(s):
Pyrokinin-4
Gene namesi
Name:PBAN
OrganismiHelicoverpa assulta (Oriental tobacco budworm) (Heliothis assulta)
Taxonomic identifieri52344 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaNoctuoideaNoctuidaeHeliothinaeHelicoverpa

Subcellular locationi

  • Secreted 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
PeptideiPRO_000002992924 – 47Diapause hormone homologSequence analysisAdd BLAST24
PropeptideiPRO_000002993051 – 94Add BLAST44
PeptideiPRO_000002993197 – 103Alpha-SG neuropeptideSequence analysis7
PeptideiPRO_0000029932106 – 123Beta-SG neuropeptideSequence analysisAdd BLAST18
PeptideiPRO_0000029933127 – 159Pheromone biosynthesis-activating neuropeptideAdd BLAST33
PeptideiPRO_0000029934162 – 169Gamma-SG neuropeptideSequence analysis8
PropeptideiPRO_0000029935172 – 194Add BLAST23

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei47Leucine amideBy similarity1
Modified residuei103Leucine amideBy similarity1
Modified residuei123Leucine amideBy similarity1
Modified residuei159Leucine amideBy similarity1
Modified residuei169Leucine amideBy similarity1

Keywords - PTMi

Amidation, Cleavage on pair of basic residues

Expressioni

Tissue specificityi

Synthesized in the subesophageal ganglion and released in the hemolymph.1 Publication

Developmental stagei

Detected in 1-3 day old adults.1 Publication

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiO18641.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pyrokinin family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR008730. PBAN.
IPR001484. Pyrokinin_CS.
PfamiView protein in Pfam
PF05874. PBAN. 1 hit.
PROSITEiView protein in PROSITE
PS00539. PYROKININ. 4 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O18641-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNQTQFFVL LAVFTTSSVL GNNNDVKDGA ASGAHSDRLG LWFGPRLGKR
60 70 80 90 100
SLRISTEDNR QAFFKLLEAA DALKYYYDQL PYEMQADEPE TRVTKKVIFT
110 120 130 140 150
PKLGRSLAYD DKSFENVEFT PRLGRRLSDD MPATPADQEM YRQDPEQIDS
160 170 180 190
RTKYFSPRLG RTMNFSPRLG RELSYDMMPN KIRVVRSANK TRST
Length:194
Mass (Da):22,343
Last modified:January 1, 1998 - v1
Checksum:i392AB211375A474D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U96761 mRNA. Translation: AAC64293.1.
AY052417 mRNA. Translation: AAL13079.2.

Similar proteinsi

Entry informationi

Entry nameiPBAN_HELAU
AccessioniPrimary (citable) accession number: O18641
Secondary accession number(s): Q95P22
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: May 10, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families