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Protein
Submitted name:

Preprocathepsin C

Gene
N/A
Organism
Schistosoma japonicum (Blood fluke)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Preprocathepsin CImported (EC:3.4.14.1Imported)
OrganismiSchistosoma japonicum (Blood fluke)Imported
Taxonomic identifieri6182 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818UniRule annotationAdd
BLAST
Chaini19 – 458440UniRule annotationPRO_5005399892Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO18533.
SMRiO18533. Positions 393-452.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini222 – 456235Pept_C1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase C1 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Family and domain databases

Gene3Di2.40.128.80. 1 hit.
InterProiIPR014882. CathepsinC_exc.
IPR033161. DPP_I.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PTHR12411:SF354. PTHR12411:SF354. 1 hit.
PfamiPF08773. CathepsinC_exc. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
SUPFAMiSSF75001. SSF75001. 1 hit.
PROSITEiPS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O18533-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFHYIIIYNL ILVTLLYGEI HCDTPANCSY MDAIGHWIFH VSRYKTKCTK
60 70 80 90 100
QLDVSQTFSM NVQYPNIVTD SYGNMGKWTL IYNQGFEITM NHRKWLIMFA
110 120 130 140 150
YGPNNTYTCN KSMPMWTHDT LICQWHCFTA TKVNHFQRMI EYKSPVLQLD
160 170 180 190 200
GNQLYKVDTK FIKAINAKQN SWKATIYPEY SKYTIKEMRR RAGGSRSAFK
210 220 230 240 250
RQNVQLPKKN LTSAMMLELL ALPKEFDWVN RPEGLRSPVT PVRNQKTCGS
260 270 280 290 300
CYAFASTAAI EARIRLASRF RLQPILSPQD IIDCSPYSEG CDGGFPYLVA
310 320 330 340 350
GKHGEDFGFV EEKCNPYTGV KSGTCNKLLG CTRYYTTDYH YIGGYYGATN
360 370 380 390 400
EDLMKLELVK NGPFPVGFEV YGDFLQYKSG VYSHTDIINN HHPFNPFELT
410 420 430 440 450
NHAVLLVGYG IDNSSNLPYW KIKNSWGQYW GEEGYFRILR GSDECGVQSI

AIKFDVVL
Length:458
Mass (Da):52,698
Last modified:January 1, 1998 - v1
Checksum:iADA9765666C4142C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U77932 mRNA. Translation: AAC32040.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U77932 mRNA. Translation: AAC32040.1.

3D structure databases

ProteinModelPortaliO18533.
SMRiO18533. Positions 393-452.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.128.80. 1 hit.
InterProiIPR014882. CathepsinC_exc.
IPR033161. DPP_I.
IPR000169. Pept_cys_AS.
IPR025660. Pept_his_AS.
IPR013128. Peptidase_C1A.
IPR000668. Peptidase_C1A_C.
[Graphical view]
PANTHERiPTHR12411. PTHR12411. 1 hit.
PTHR12411:SF354. PTHR12411:SF354. 1 hit.
PfamiPF08773. CathepsinC_exc. 1 hit.
PF00112. Peptidase_C1. 1 hit.
[Graphical view]
PRINTSiPR00705. PAPAIN.
SMARTiSM00645. Pept_C1. 1 hit.
[Graphical view]
SUPFAMiSSF75001. SSF75001. 1 hit.
PROSITEiPS00139. THIOL_PROTEASE_CYS. 1 hit.
PS00639. THIOL_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO18533_SCHJA
AccessioniPrimary (citable) accession number: O18533
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 11, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.