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Protein

Styelin-D

Gene
N/A
Organism
Styela clava (Sea squirt)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Bactericidal against several Gram-positive and Gram-negative bacteria. Plays a significant role in the innate immune mechanisms of S.clava.

GO - Biological processi

Keywordsi

Molecular functionAntibiotic, Antimicrobial

Protein family/group databases

TCDBi1.C.17.2.1. the cecropin (cecropin) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Styelin-D
OrganismiStyela clava (Sea squirt)
Taxonomic identifieri7725 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaeStyela

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
PeptideiPRO_000002243623 – 54Styelin-D1 PublicationAdd BLAST32
PropeptideiPRO_000002243756 – 81Removed in mature formAdd BLAST26

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei246'-bromotryptophan1 Publication1
Modified residuei263,4-dihydroxyarginine1 Publication1
Modified residuei274,5-dihydroxylysine1 Publication1
Modified residuei304,5-dihydroxylysine1 Publication1
Modified residuei344,5-dihydroxylysine1 Publication1
Modified residuei363',4'-dihydroxyphenylalanine1 Publication1
Modified residuei373',4'-dihydroxyphenylalanine1 Publication1
Modified residuei384,5-dihydroxylysine1 Publication1
Modified residuei405-hydroxylysine1 Publication1
Modified residuei413',4'-dihydroxyphenylalanine1 Publication1
Modified residuei423',4'-dihydroxyphenylalanine1 Publication1
Modified residuei445-hydroxylysine1 Publication1
Modified residuei54Leucine amide1 Publication1

Post-translational modificationi

Contains L-DOPA (3',4'-dihydroxyphenylalanine).

Keywords - PTMi

Amidation, Bromination, Hydroxylation

Expressioni

Tissue specificityi

Hemocytes and pharyngeal tissues.

Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

HOVERGENiHBG006845.

Family and domain databases

InterProiView protein in InterPro
IPR035578. Styelin.
PfamiView protein in Pfam
PF17562. Styelin. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD865040. PD865040. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O18495-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQMKATILIV LVALFMIQQS EAGWLRKAAK SVGKFYYKHK YYIKAAWQIG
60 70 80
KHALGDMTDE EFQDFMKEVE QAREEELQSR Q
Length:81
Mass (Da):9,560
Last modified:January 1, 1998 - v1
Checksum:iE2F71DD39287D443
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y13269 mRNA. Translation: CAA73718.1.

Similar proteinsi

Entry informationi

Entry nameiSTYD_STYCL
AccessioniPrimary (citable) accession number: O18495
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 1, 1998
Last modified: August 30, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing