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O18483

- O18483_ONCVO

UniProt

O18483 - O18483_ONCVO

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Protein

Superoxide dismutase [Cu-Zn]

Gene

OvSOD2

Organism
Onchocerca volvulus
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Binds 1 copper ion per subunit.UniRule annotation
Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:OvSOD2Imported
Synonyms:WBGene00248325Imported
OrganismiOnchocerca volvulusImported
Taxonomic identifieri6282 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaSpiruridaFilarioideaOnchocercidaeOnchocerca

Structurei

3D structure databases

ProteinModelPortaliO18483.
SMRiO18483. Positions 44-198.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
PRINTSiPR00068. CUZNDISMTASE.
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O18483-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MINSFIVIFL SFLIFINYAN LVYVEATHVY GRRSHSNGMH GNGARRAVAV
60 70 80 90 100
LRGDAGVSGI IYFQQDSGGS ITTISGSVSG LTPGLHGFHV HQYGDQTNGC
110 120 130 140 150
TSAGGHYNPY GKTHGDPNDR IKHIGDLGNI VAGANGVAEV YINSYHIKLR
160 170 180 190 200
GPLSVIGRSL VVHENPDDLG QGTGNMREES LKTGNAGSRL ACAVIGIAAV

S
Length:201
Mass (Da):21,148
Last modified:January 1, 1998 - v1
Checksum:i9BD9E833C71AEE5C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L13778 Genomic DNA. No translation available.
AF009621 Genomic DNA. Translation: AAB64227.1.

Genome annotation databases

EnsemblMetazoaiOVOC11516; OVOC11516; WBGene00248325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L13778 Genomic DNA. No translation available.
AF009621 Genomic DNA. Translation: AAB64227.1 .

3D structure databases

ProteinModelPortali O18483.
SMRi O18483. Positions 44-198.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai OVOC11516 ; OVOC11516 ; WBGene00248325 .

Family and domain databases

Gene3Di 2.60.40.200. 1 hit.
InterProi IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view ]
Pfami PF00080. Sod_Cu. 1 hit.
[Graphical view ]
PRINTSi PR00068. CUZNDISMTASE.
SUPFAMi SSF49329. SSF49329. 1 hit.
PROSITEi PS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Tawe W., Eschbach M.-L., Walter R.D., Henkle-Duehrsen K.J.
    Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Genome sequencing of Onchocerca volvulus."
    Cotton J., Tsai J., Stanley E., Tracey A., Holroyd N., Lustigman S., Berriman M.
    Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. EnsemblMetazoa
    Submitted (MAY-2014) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiO18483_ONCVO
AccessioniPrimary (citable) accession number: O18483
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: October 1, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)