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O18483

- O18483_ONCVO

UniProt

O18483 - O18483_ONCVO

Protein

Superoxide dismutase [Cu-Zn]

Gene

OvSOD2

Organism
Onchocerca volvulus
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Jan 1998)
      Previous versions | rss
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    Functioni

    Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

    Catalytic activityi

    2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

    Cofactori

    Binds 1 copper ion per subunit.UniRule annotation
    Binds 1 zinc ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. superoxide dismutase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Ligandi

    CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
    Gene namesi
    Name:OvSOD2Imported
    Synonyms:WBGene00248325Imported
    OrganismiOnchocerca volvulusImported
    Taxonomic identifieri6282 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaSpiruridaFilarioideaOnchocercidaeOnchocerca

    Structurei

    3D structure databases

    ProteinModelPortaliO18483.
    SMRiO18483. Positions 44-198.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

    Family and domain databases

    Gene3Di2.60.40.200. 1 hit.
    InterProiIPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view]
    PfamiPF00080. Sod_Cu. 1 hit.
    [Graphical view]
    PRINTSiPR00068. CUZNDISMTASE.
    SUPFAMiSSF49329. SSF49329. 1 hit.
    PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
    PS00332. SOD_CU_ZN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O18483-1 [UniParc]FASTAAdd to Basket

    « Hide

    MINSFIVIFL SFLIFINYAN LVYVEATHVY GRRSHSNGMH GNGARRAVAV    50
    LRGDAGVSGI IYFQQDSGGS ITTISGSVSG LTPGLHGFHV HQYGDQTNGC 100
    TSAGGHYNPY GKTHGDPNDR IKHIGDLGNI VAGANGVAEV YINSYHIKLR 150
    GPLSVIGRSL VVHENPDDLG QGTGNMREES LKTGNAGSRL ACAVIGIAAV 200
    S 201
    Length:201
    Mass (Da):21,148
    Last modified:January 1, 1998 - v1
    Checksum:i9BD9E833C71AEE5C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L13778 Genomic DNA. No translation available.
    AF009621 Genomic DNA. Translation: AAB64227.1.

    Genome annotation databases

    EnsemblMetazoaiOVOC11516; OVOC11516; WBGene00248325.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L13778 Genomic DNA. No translation available.
    AF009621 Genomic DNA. Translation: AAB64227.1 .

    3D structure databases

    ProteinModelPortali O18483.
    SMRi O18483. Positions 44-198.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai OVOC11516 ; OVOC11516 ; WBGene00248325 .

    Family and domain databases

    Gene3Di 2.60.40.200. 1 hit.
    InterProi IPR018152. SOD_Cu/Zn_BS.
    IPR001424. SOD_Cu_Zn_dom.
    [Graphical view ]
    Pfami PF00080. Sod_Cu. 1 hit.
    [Graphical view ]
    PRINTSi PR00068. CUZNDISMTASE.
    SUPFAMi SSF49329. SSF49329. 1 hit.
    PROSITEi PS00087. SOD_CU_ZN_1. 1 hit.
    PS00332. SOD_CU_ZN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Tawe W., Eschbach M.-L., Walter R.D., Henkle-Duehrsen K.J.
      Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Genome sequencing of Onchocerca volvulus."
      Cotton J., Tsai J., Stanley E., Tracey A., Holroyd N., Lustigman S., Berriman M.
      Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. EnsemblMetazoa
      Submitted (MAY-2014) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiO18483_ONCVO
    AccessioniPrimary (citable) accession number: O18483
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 1, 1998
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)