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O18483

- O18483_ONCVO

UniProt

O18483 - O18483_ONCVO

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Protein
Superoxide dismutase [Cu-Zn]
Gene
OvSOD2, WBGene00248325
Organism
Onchocerca volvulus
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Binds 1 copper ion per subunit By similarity.UniRule annotation
Binds 1 zinc ion per subunit By similarity.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:OvSOD2Imported
Synonyms:WBGene00248325Imported
OrganismiOnchocerca volvulusImported
Taxonomic identifieri6282 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaSpiruridaFilarioideaOnchocercidaeOnchocerca

Structurei

3D structure databases

ProteinModelPortaliO18483.
SMRiO18483. Positions 44-198.

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
PRINTSiPR00068. CUZNDISMTASE.
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O18483-1 [UniParc]FASTAAdd to Basket

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MINSFIVIFL SFLIFINYAN LVYVEATHVY GRRSHSNGMH GNGARRAVAV    50
LRGDAGVSGI IYFQQDSGGS ITTISGSVSG LTPGLHGFHV HQYGDQTNGC 100
TSAGGHYNPY GKTHGDPNDR IKHIGDLGNI VAGANGVAEV YINSYHIKLR 150
GPLSVIGRSL VVHENPDDLG QGTGNMREES LKTGNAGSRL ACAVIGIAAV 200
S 201
Length:201
Mass (Da):21,148
Last modified:January 1, 1998 - v1
Checksum:i9BD9E833C71AEE5C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L13778 Genomic DNA. No translation available.
AF009621 Genomic DNA. Translation: AAB64227.1.

Genome annotation databases

EnsemblMetazoaiOVOC11516; OVOC11516; WBGene00248325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L13778 Genomic DNA. No translation available.
AF009621 Genomic DNA. Translation: AAB64227.1 .

3D structure databases

ProteinModelPortali O18483.
SMRi O18483. Positions 44-198.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai OVOC11516 ; OVOC11516 ; WBGene00248325 .

Family and domain databases

Gene3Di 2.60.40.200. 1 hit.
InterProi IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view ]
Pfami PF00080. Sod_Cu. 1 hit.
[Graphical view ]
PRINTSi PR00068. CUZNDISMTASE.
SUPFAMi SSF49329. SSF49329. 1 hit.
PROSITEi PS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Tawe W., Eschbach M.-L., Walter R.D., Henkle-Duehrsen K.J.
    Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Genome sequencing of Onchocerca volvulus."
    Cotton J., Tsai J., Stanley E., Tracey A., Holroyd N., Lustigman S., Berriman M.
    Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. EnsemblMetazoa
    Submitted (MAY-2014) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiO18483_ONCVO
AccessioniPrimary (citable) accession number: O18483
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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