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Protein

Integrin beta

Gene
N/A
Organism
Ophlitaspongia tenuis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IntegrinUniRule annotationSAAS annotationImported

Keywords - Biological processi

Cell adhesionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Integrin betaUniRule annotation
OrganismiOphlitaspongia tenuisImported
Taxonomic identifieri61613 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPoriferaDemospongiaeHeteroscleromorphaPoeciloscleridaClathriidaeOphlitaspongia

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei771 – 79929HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 838819Integrin betaSequence analysisPRO_5004157402Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO18482.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini36 – 458423INBInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the integrin beta chain family.UniRule annotation
Contains VWFA domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR013111. EGF_extracell.
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR002369. Integrin_bsu_N.
IPR032695. Integrin_dom.
IPR016201. Plexin-like_fold.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 2 hits.
PfamiPF07974. EGF_2. 1 hit.
PF08725. Integrin_b_cyt. 1 hit.
PF00362. Integrin_beta. 1 hit.
[Graphical view]
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiSM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
[Graphical view]
SUPFAMiSSF103575. SSF103575. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
PROSITEiPS00243. INTEGRIN_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O18482-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGLQWSILG SLLVGVVYGQ TGLDPALGRL CNAQVSCGDC IFSSPNCVWC
60 70 80 90 100
ADQNYNGTRC YAIGDPDFEN LCSGMEQNPM GEITDTVDPP LQDLTQVSPS
110 120 130 140 150
RVSINVRPGQ PQTFNLNVRP ARNFPIDLYL LMDLSYSMRD DLDNLKQLGA
160 170 180 190 200
DLAASIVGLS TNFRIGFGSF VEKVVAPFTT LDVRFQQNPC LNRNDIVCEP
210 220 230 240 250
TYSYRHIISL TDDADEFNDL VQEQMISGNQ DLPEGGFDGF LQSLLCTNLI
260 270 280 290 300
GWRDVSRKLL LYITDAGFHF AGDGKLGGLI LPHQSICRLP NSGPHTGSVP
310 320 330 340 350
VEYMDAELFD YPSVGQIAQA LREQDIIPIF AAQRDAREFY DVLAAEIGEG
360 370 380 390 400
ASTGTLASDS SNVVELVRQQ YNTISQRVIF DQEPVPGVSV VINPTSCPGG
410 420 430 440 450
VIEDGICTGL QIERVAEFDV TVSITECTPE LLFQEISIPL RVVGFGELEI
460 470 480 490 500
VLNALCRCEC EDTESPNDPA CSGSGTLSCG QCVCNPDNFG EFCQCDATNP
510 520 530 540 550
NAQLDCPAGD SNIQCTGRGT CLCGICDCDP GFFGQACECD ERDCINQDSG
560 570 580 590 600
LLCSGRGSCG CDGRCTCNVE PVSQLPYNGD LNVCECTPNT QNCRDPTNRT
610 620 630 640 650
SICNGRGACG CDGSCECEDP YFGQFCELCS GSEICFDTNC DSNRDCANCA
660 670 680 690 700
LDIIVQMVET TSVMEFFANA ESNPNLPEGS MVSFDSENNA MQVVLPQGQC
710 720 730 740 750
PLCDAGAVII NGTERADYQI DGEMAVRCEE VRDGCVYRYF VGIAATTDNF
760 770 780 790 800
TAVHVEYARS CPDQQGGTAP WIIAISIIIP LIVLGLLLLL LLKGLLLLWD
810 820 830
VVEVRKFERE IKNAKYTKNE NPLYRSATKD YQNPLYGK
Length:838
Mass (Da):91,114
Last modified:January 1, 1998 - v1
Checksum:iB91D13F613F2A3CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF005357 mRNA. Translation: AAB66911.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF005357 mRNA. Translation: AAB66911.1.

3D structure databases

ProteinModelPortaliO18482.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR013111. EGF_extracell.
IPR015812. Integrin_bsu.
IPR014836. Integrin_bsu_cyt_dom.
IPR002369. Integrin_bsu_N.
IPR032695. Integrin_dom.
IPR016201. Plexin-like_fold.
IPR002035. VWF_A.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 2 hits.
PfamiPF07974. EGF_2. 1 hit.
PF08725. Integrin_b_cyt. 1 hit.
PF00362. Integrin_beta. 1 hit.
[Graphical view]
PIRSFiPIRSF002512. Integrin_B. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiSM00187. INB. 1 hit.
SM01241. Integrin_b_cyt. 1 hit.
[Graphical view]
SUPFAMiSSF103575. SSF103575. 1 hit.
SSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 1 hit.
PROSITEiPS00243. INTEGRIN_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular evolution of integrins: genes encoding integrin beta subunits from a coral and a sponge."
    Brower D.L., Brower S.M., Hayward D.C., Ball E.E.
    Proc. Natl. Acad. Sci. U.S.A. 94:9182-9187(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO18482_9METZ
AccessioniPrimary (citable) accession number: O18482
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 11, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.