O18476 (O18476_DORPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Kv2 voltage-gated potassium channel EMBL CAA74748.1
Organism	Doryteuthis pealeii (Longfin inshore squid) (Loligo pealeii) EMBL CAA74748.1
Taxonomic identifier	1051067 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Cephalopoda › Coleoidea › Neocoleoidea › Decapodiformes › Teuthida › Myopsina › Loliginidae › Doryteuthis

Protein attributes

Sequence length	908 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Potassium transport Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS003091
Ligand	Potassium
Molecular function	Ion channel Potassium channel SAAS SAAS003091 Voltage-gated channel SAAS SAAS003091
Gene Ontology (GO)
Biological_process	protein homooligomerization Inferred from electronic annotation. Source: InterPro
Cellular_component	voltage-gated potassium channel complex Inferred from electronic annotation. Source: InterPro
Molecular_function	voltage-gated potassium channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O18476 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: D2B68040ABFB6DA4	FASTA	908	99,369
	10 20 30 40 50 60 MMLPVNDRRA SVAVPSWSSG PFLSGAGSDR GSDLTSATSL AASRNASLRH QRRQHPSSVG 70 80 90 100 110 120 IRRRDPSLSA NTSASDHHRH FPHRHPRHRH RRHPPPLLSS TTAASTRDPA SATSGSVRKQ 130 140 150 160 170 180 SGRSEVKIAP GPIVSGGGGG SIQLAASPAV VQPTGSIVAG GNNNLPLQGG GGGGGGGGVG 190 200 210 220 230 240 GGGVVGVGVG DMSSALRRPF YAASSIGSPP DPASILRSGE VSRRVILNVG GVKHEVLWRT 250 260 270 280 290 300 LDRVPHTRLG KLKDCNTHDA IVDLCDDYSL AENEYFFDRH PRSFASILNF YRTGKLHLVE 310 320 330 340 350 360 EMCVLAFSED LEYWGVDELY LESCCQHKYH QKKEHVFEEI RKEAESLRKG EDEDFGTGSF 370 380 390 400 410 420 AKWRQRVWDL LEKPTTSMAA RVLAIVSILF VVLSTVALTL NTIPGLKGEG EHEGADNPQL 430 440 450 460 470 480 AIVEAVCIGW FTLEYLGRFW ASPNKWKFFK GPLNIIDLLA ILPYFISLGL TETNKSTTEQ 490 500 510 520 530 540 FQNVRRVVRV FRIMRVLRIL KLARHSTGLQ SLGYTLQRSY KELGLLMMFL AIGILLFSSL 550 560 570 580 590 600 AYFAEKDEPG TKYVSIPETF WWAAITMTTV GYGDICPTTI LGKVVGGVCC ICGVLVVALP 610 620 630 640 650 660 IPIIVNNFAE FYKDQMRREK ALKRKEALER AKRNGSIVSF HSVNLRDAFA KSVDLMDVAS 670 680 690 700 710 720 EVPRNDWDTN SVETRSMSSP PPCVMRGSNP NTPKLSGQGG TPNFDCKENQ ENPSNTNLLD 730 740 750 760 770 780 IDEESLHRMT TTQASNEPSL QNQFEFPSDA MTDLDCDNKG CIEMKTLPRQ ESTASTDTYA 790 800 810 820 830 840 SCFTHPQSSP SITGRPNDAS NQANICVNPL EEPSYQGQLP SYESVIQSDF INCPSNHENG 850 860 870 880 890 900 NINYQKAPPL GRAVCQSFSG SVNRPSDQIV QKIEDGLTAT WPGIQSFPSP RLIATTRLKS PVCPTIYP

References

[1]	"RNA editing generates a diverse array of transcripts encoding squid Kv2 K+ channels with altered functional properties." Patton D.E., Silva T., Bezanilla F. Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Optic lobe EMBL CAA74748.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y14390 mRNA. Translation: CAA74748.1.
3D structure databases
HSSP	HSSP built from PDB template 3KVT based on UniProtKB O76457.
ProteinModelPortal	O18476.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.30.710.10. 1 hit.
InterPro	IPR000210. BTB/POZ-like. IPR011333. BTB/POZ_fold. IPR005821. Ion_trans_dom. IPR003091. K_chnl. IPR003968. K_chnl_volt-dep_Kv. IPR003971. K_chnl_volt-dep_Kv9. IPR003131. T1-type_BTB. [Graphical view]
PANTHER	PTHR11537. PTHR11537. 1 hit.
Pfam	PF00520. Ion_trans. 1 hit. PF02214. K_tetra. 1 hit. [Graphical view]
PRINTS	PR00169. KCHANNEL. PR01494. KV9CHANNEL. PR01491. KVCHANNEL.
SMART	SM00225. BTB. 1 hit. [Graphical view]
SUPFAM	SSF54695. BTB/POZ_fold. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O18476_DORPE

Accession

Primary (citable) accession number: O18476

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	March 6, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)