Fizzy-related protein - Drosophila melanogaster (Fruit fly)

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Unreviewed, UniProtKB/TrEMBL O18402 (O18402_DROME)

Last modified June 16, 2009. Version 63. History...

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Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
Fizzy-related protein EMBL CAA74575.1

Gene names

Name:	rap FlyBase FBgn0003200
Synonyms:	fzr EMBL CAA74575.1
ORF Names:	CG3000 FlyBase FBgn0003200

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL CAA74575.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	478 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Domain	WD repeat RuleBase RU000362V4
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	compound eye morphogenesis Inferred from mutant phenotype. Source: FlyBase cyclin catabolic process Ref.1 Inferred from direct assay. Source: FlyBase eye-antennal disc morphogenesis Inferred from mutant phenotype. Source: FlyBase positive regulation of exit from mitosis Inferred from mutant phenotype. Source: FlyBase
Cellular component	centriole Inferred from direct assay. Source: FlyBase spindle Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

O18402-1 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 752B799F43762439
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478

53,507

        10         20         30         40         50         60 
MFSPEYQKRI LKHYSPVARN LFNNFESSTT PTSLDRFIPC RAYNNWQTNF ASINKSNDNS 

        70         80         90        100        110        120 
PQTSKKQRDC GETARDSLAY SCLLKNELLG SAIDDVKTAG EERNENAYTP AAKRSLFKYQ 

       130        140        150        160        170        180 
SPTKQDYNGE CPYSLSPVSA KSQKLLRSPR KATRKISRIP FKVLDAPELQ DDFYLNLVDW 

       190        200        210        220        230        240 
SSQNVLAVGL GSCVYLWSAC TSQVTRLCDL SPDANTVTSV SWNERGNTVA VGTHHGYVTV 

       250        260        270        280        290        300 
WDVAANKQIN KLNGHSARVG ALAWNSDILS SGSRDRWIIQ RDTRTPQLQS ERRLAGHRQE 

       310        320        330        340        350        360 
VCGLKWSPDN QYLASGGNDN RLYVWNQHSV NPVQSYTEHM AAVKAIAWSP HHHGLLASGG 

       370        380        390        400        410        420 
GTADRCIRFW NTLTGQPMQC VDTGSQVCNL AWSKHSSELV STHGYSQNQI LVWKYPSLTQ 

       430        440        450        460        470 
VAKLTGHSYR VLYLALSPDG EAIVTGAGDE TLRFWNVFSK ARSQKENKSV LNLFANIR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles." Sigrist S.J., Lehner C.F. Cell 90:671-681(1997) [PubMed: 9288747] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

Cross-references

Sequence databases
	Y14162 mRNA. Translation: CAA74575.1.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	O18402.
Genome annotation databases
Ensembl	FBgn0003200. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0003200. rap.
Phylogenomic databases
HOGENOM	O18402.
Gene expression databases
ArrayExpress	O18402.
Family and domain databases
InterPro	IPR015943. WD40/YVTN_repeat-like. IPR001680. WD40_repeat. IPR019782. WD40_repeat_2. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_region. IPR019781. WD40_repeat_sg. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF00400. WD40. 5 hits. [Graphical view]
ProDom	PD004563. Fizzy. 1 hit. PD000018. WD40. 2 hits. [Graphical view] [Entries sharing at least one domain]
SMART	SM00320. WD40. 7 hits. [Graphical view]
PROSITE	PS00678. WD_REPEATS_1. 2 hits. PS50082. WD_REPEATS_2. 3 hits. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O18402_DROME

Accession

Primary (citable) accession number: O18402

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	June 16, 2009
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequences · References · Cross-references · Entry information