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Protein
Submitted name:

LD44762p

Gene

Rab8

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • polarized secretion of basement membrane proteins in epithelium Source: FlyBase
  • protein localization to plasma membrane Source: GO_Central
  • protein secretion Source: GO_Central
  • Rab protein signal transduction Source: FlyBase
  • regulation of exocytosis Source: GO_Central
  • regulation of synaptic growth at neuromuscular junction Source: FlyBase
  • sleep Source: FlyBase
  • vesicle docking involved in exocytosis Source: GO_Central
  • vesicle-mediated transport Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-5620916. VxPx cargo-targeting to cilium.
R-DME-8873719. RAB geranylgeranylation.

Names & Taxonomyi

Protein namesi
Submitted name:
LD44762pImported
Submitted name:
Rab8Imported
Submitted name:
Rab8, isoform AImported
Submitted name:
Rab8, isoform CImported
Gene namesi
Name:Rab8Imported
Synonyms:AAF49101Imported, Dm Rab8Imported, dm-Rab8Imported, Dmel\CG8287Imported, DmRab8Imported, DRAB8Imported, DRab8Imported, l(3)76BDuImported, O18338Imported, Rab-r8Imported, rab8Imported
ORF Names:CG8287Imported, Dmel_CG8287Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0262518. Rab8.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0262518.

Interactioni

Protein-protein interaction databases

IntActiO18338. 1 interactor.
MINTiMINT-864123.
STRINGi7227.FBpp0074690.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0078. Eukaryota.
ENOG410XPUI. LUCA.
GeneTreeiENSGT00890000139330.
OMAiNRKMNDG.
OrthoDBiEOG091G0LA6.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

O18338-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKTYDYLFK LLLIGDSGVG KTCILFRFSE DAFNTTFIST IGIDFKIRTI
60 70 80 90 100
ELDNKKIKLQ IWDTAGQERF RTITTAYYRG AMGIMLVYDI TQEKSFENIK
110 120 130 140 150
NWIRNIEENA SADVEKMLLG NKCELTDKRQ VSKERGEQLA IEYGIKFMET
160 170 180 190 200
SAKASINVEE AFLTLASDIK AKTEKRMEAN NPPKGGHQLK PMDSRTKDSW

LSRCSLL
Length:207
Mass (Da):23,691
Last modified:January 1, 1998 - v1
Checksum:iBE9DE812C77DCF09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014296 Genomic DNA. Translation: AAF49101.1.
AY069671 mRNA. Translation: AAL39816.1.
AE014296 Genomic DNA. Translation: AFH04508.1.
D84347 mRNA. Translation: BAA21711.1.
AB112933 mRNA. Translation: BAD07038.1.
RefSeqiNP_001246837.1. NM_001259908.2.
NP_524172.1. NM_079448.4.
UniGeneiDm.2015.

Genome annotation databases

EnsemblMetazoaiFBtr0074921; FBpp0074690; FBgn0262518.
FBtr0308833; FBpp0300990; FBgn0262518.
GeneIDi40168.
UCSCiCG8287-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiO18338_DROME
AccessioniPrimary (citable) accession number: O18338
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: September 27, 2017
This is version 155 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported