Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Drab11

Gene

Rab11

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activating protein binding Source: FlyBase
  • GTPase activity Source: FlyBase
  • GTP binding Source: InterPro
  • protein-containing complex binding Source: FlyBase

GO - Biological processi

  • actin cytoskeleton reorganization Source: FlyBase
  • actomyosin contractile ring contraction Source: FlyBase
  • adherens junction maintenance Source: FlyBase
  • antimicrobial humoral response Source: FlyBase
  • border follicle cell migration Source: FlyBase
  • cellularization Source: FlyBase
  • centrosome localization Source: FlyBase
  • chaeta development Source: FlyBase
  • compound eye development Source: FlyBase
  • compound eye morphogenesis Source: FlyBase
  • cortical actin cytoskeleton organization Source: FlyBase
  • dorsal closure Source: FlyBase
  • dorsal closure, amnioserosa morphology change Source: FlyBase
  • dorsal closure, elongation of leading edge cells Source: FlyBase
  • endocytic recycling Source: FlyBase
  • endocytosis Source: FlyBase
  • exosomal secretion Source: FlyBase
  • fusome organization Source: FlyBase
  • germ-line stem cell division Source: FlyBase
  • germ-line stem cell population maintenance Source: FlyBase
  • Golgi vesicle fusion to target membrane Source: FlyBase
  • male meiosis cytokinesis Source: FlyBase
  • negative regulation of synaptic growth at neuromuscular junction Source: FlyBase
  • oocyte development Source: FlyBase
  • oocyte microtubule cytoskeleton polarization Source: FlyBase
  • oogenesis Source: FlyBase
  • ovarian follicle cell development Source: FlyBase
  • ovarian fusome organization Source: FlyBase
  • positive regulation of Golgi to plasma membrane protein transport Source: FlyBase
  • Rab protein signal transduction Source: FlyBase
  • regulation of pole plasm oskar mRNA localization Source: FlyBase
  • regulation of synapse organization Source: FlyBase
  • rhabdomere development Source: FlyBase
  • sensory organ precursor cell fate determination Source: FlyBase
  • spermatocyte division Source: FlyBase
  • synaptic vesicle endocytosis Source: FlyBase
  • vesicle-mediated transport Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-432040 Vasopressin regulates renal water homeostasis via Aquaporins
R-DME-5620916 VxPx cargo-targeting to cilium
R-DME-8873719 RAB geranylgeranylation

Names & Taxonomyi

Protein namesi
Submitted name:
Drab11Imported
Submitted name:
GM06568pImported
Submitted name:
RE11886pImported
Submitted name:
Rab11Imported
Submitted name:
Rab11, isoform AImported
Submitted name:
Rab11, isoform BImported
Gene namesi
Name:Rab11Imported
Synonyms:AAF55850Imported, Dm Rab11Imported, Dmel\CG5771Imported, DmRab11Imported, DRAB11Imported, DRab11Imported, Drab11Imported, dRab11Imported, l(3)93BiImported, l(3)j2D1Imported, O18335Imported, Rab 11Imported, Rab-11Imported, rab-11Imported, Rab-r11Imported, RAB11Imported, rab11Imported, rlr7Imported
ORF Names:CG5771Imported, Dmel_CG5771Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0015790 Rab11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiO18335

Expressioni

Gene expression databases

BgeeiFBgn0015790
ExpressionAtlasiO18335 baseline and differential

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CragO969572EBI-148897,EBI-868608

GO - Molecular functioni

  • GTPase activating protein binding Source: FlyBase

Protein-protein interaction databases

DIPiDIP-47764N
IntActiO18335, 5 interactors
STRINGi7227.FBpp0083413

Structurei

3D structure databases

SMRiO18335
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0087 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00760000118841
KOiK07904
OMAiKHSTYES
OrthoDBiEOG091G0O1R

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit

Sequencei

Sequence statusi: Complete.

O18335-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAREDEYDY LFKVVLIGDS GVGKSNLLSR FTRNEFNLES KSTIGVEFAT
60 70 80 90 100
RSIEVDGKTI KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE
110 120 130 140 150
NVERWLRELR DHADQNIVIM LVGNKSDLRH LRSVPTDEAK LFAERNGLSF
160 170 180 190 200
IETSALDSTN VETAFQNILT EIYRIVSQKQ IRDPPEGDVI RPSNVEPIDV
210
KPTVTADVRK QCCQ
Length:214
Mass (Da):24,245
Last modified:January 1, 1998 - v1
Checksum:i6033C911EFA74D89
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55850.1
AY070528 mRNA Translation: AAL47999.1
AY113404 mRNA Translation: AAM29409.1
AE014297 Genomic DNA Translation: AAN13849.1
D84315 mRNA Translation: BAA21708.1
AB035354 mRNA Translation: BAA87880.1
RefSeqiNP_477170.1, NM_057822.4
NP_599137.1, NM_134310.3
UniGeneiDm.3038

Genome annotation databases

EnsemblMetazoaiFBtr0084010; FBpp0083413; FBgn0015790
FBtr0084011; FBpp0083414; FBgn0015790
GeneIDi42501
KEGGidme:Dmel_CG5771
UCSCiCG5771-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiO18335_DROME
AccessioniPrimary (citable) accession number: O18335
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 171 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health