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Protein
Submitted name:

Drab11

Gene

Rab11

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activating protein binding Source: FlyBase
  • GTPase activity Source: FlyBase
  • GTP binding Source: InterPro
  • protein complex binding Source: FlyBase

GO - Biological processi

  • actin cytoskeleton reorganization Source: FlyBase
  • actomyosin contractile ring contraction Source: FlyBase
  • adherens junction maintenance Source: FlyBase
  • antimicrobial humoral response Source: FlyBase
  • border follicle cell migration Source: FlyBase
  • cellularization Source: FlyBase
  • centrosome localization Source: FlyBase
  • chaeta development Source: FlyBase
  • compound eye development Source: FlyBase
  • compound eye morphogenesis Source: FlyBase
  • cortical actin cytoskeleton organization Source: FlyBase
  • dorsal closure Source: FlyBase
  • dorsal closure, amnioserosa morphology change Source: FlyBase
  • dorsal closure, elongation of leading edge cells Source: FlyBase
  • endocytic recycling Source: FlyBase
  • endocytosis Source: FlyBase
  • epithelium development Source: FlyBase
  • exosomal secretion Source: FlyBase
  • fusome organization Source: FlyBase
  • germarium-derived egg chamber formation Source: FlyBase
  • germ-line stem cell division Source: FlyBase
  • germ-line stem cell population maintenance Source: FlyBase
  • Golgi vesicle fusion to target membrane Source: FlyBase
  • male meiosis cytokinesis Source: FlyBase
  • negative regulation of synaptic growth at neuromuscular junction Source: FlyBase
  • oocyte development Source: FlyBase
  • oocyte microtubule cytoskeleton polarization Source: FlyBase
  • oogenesis Source: FlyBase
  • ovarian follicle cell development Source: FlyBase
  • ovarian fusome organization Source: FlyBase
  • positive regulation of Golgi to plasma membrane protein transport Source: FlyBase
  • Rab protein signal transduction Source: FlyBase
  • regulation of pole plasm oskar mRNA localization Source: FlyBase
  • regulation of synapse organization Source: FlyBase
  • rhabdomere development Source: FlyBase
  • sensory organ precursor cell fate determination Source: FlyBase
  • spermatocyte division Source: FlyBase
  • vesicle-mediated transport Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-432040. Vasopressin regulates renal water homeostasis via Aquaporins.
R-DME-5620916. VxPx cargo-targeting to cilium.
R-DME-8873719. RAB geranylgeranylation.

Names & Taxonomyi

Protein namesi
Submitted name:
Drab11Imported
Submitted name:
GM06568pImported
Submitted name:
RE11886pImported
Submitted name:
Rab11Imported
Submitted name:
Rab11, isoform AImported
Submitted name:
Rab11, isoform BImported
Gene namesi
Name:Rab11Imported
Synonyms:AAF55850Imported, Dm Rab11Imported, Dmel\CG5771Imported, DmRab11Imported, DRAB11Imported, DRab11Imported, Drab11Imported, dRab11Imported, l(3)93BiImported, l(3)j2D1Imported, O18335Imported, Rab 11Imported, Rab-11Imported, rab-11Imported, Rab-r11Imported, RAB11Imported, rab11Imported, rlr7Imported
ORF Names:CG5771Imported, Dmel_CG5771Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0015790. Rab11.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0015790.

Interactioni

GO - Molecular functioni

  • GTPase activating protein binding Source: FlyBase
  • protein complex binding Source: FlyBase

Protein-protein interaction databases

DIPiDIP-47764N.
IntActiO18335. 9 interactors.
MINTiMINT-758893.
STRINGi7227.FBpp0083413.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0087. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00760000118841.
KOiK07904.
OMAiANSTACK.
OrthoDBiEOG091G0O1R.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

O18335-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAREDEYDY LFKVVLIGDS GVGKSNLLSR FTRNEFNLES KSTIGVEFAT
60 70 80 90 100
RSIEVDGKTI KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE
110 120 130 140 150
NVERWLRELR DHADQNIVIM LVGNKSDLRH LRSVPTDEAK LFAERNGLSF
160 170 180 190 200
IETSALDSTN VETAFQNILT EIYRIVSQKQ IRDPPEGDVI RPSNVEPIDV
210
KPTVTADVRK QCCQ
Length:214
Mass (Da):24,245
Last modified:January 1, 1998 - v1
Checksum:i6033C911EFA74D89
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA. Translation: AAF55850.1.
AY070528 mRNA. Translation: AAL47999.1.
AY113404 mRNA. Translation: AAM29409.1.
AE014297 Genomic DNA. Translation: AAN13849.1.
D84315 mRNA. Translation: BAA21708.1.
AB035354 mRNA. Translation: BAA87880.1.
RefSeqiNP_477170.1. NM_057822.4.
NP_599137.1. NM_134310.3.
UniGeneiDm.3038.

Genome annotation databases

EnsemblMetazoaiFBtr0084010; FBpp0083413; FBgn0015790.
FBtr0084011; FBpp0083414; FBgn0015790.
GeneIDi42501.
KEGGidme:Dmel_CG5771.
UCSCiCG5771-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiO18335_DROME
AccessioniPrimary (citable) accession number: O18335
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: September 27, 2017
This is version 164 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported