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Protein
Submitted name:

FI01544p

Gene

Rab1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: FlyBase
  • GTP binding Source: InterPro

GO - Biological processi

  • anterograde axonal transport Source: FlyBase
  • carbohydrate homeostasis Source: FlyBase
  • ER to Golgi vesicle-mediated transport Source: FlyBase
  • Golgi organization Source: FlyBase
  • male meiosis cytokinesis Source: FlyBase
  • mitotic cytokinesis Source: FlyBase
  • positive regulation of dendrite morphogenesis Source: FlyBase
  • positive regulation of insulin secretion Source: FlyBase
  • protein localization to cleavage furrow Source: FlyBase
  • protein localization to Golgi apparatus Source: FlyBase
  • protein secretion Source: FlyBase
  • Rab protein signal transduction Source: FlyBase
  • regulation of cell migration Source: FlyBase
  • vesicle-mediated transport Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-162658 Golgi Cisternae Pericentriolar Stack Reorganization
R-DME-204005 COPII-mediated vesicle transport
R-DME-6807878 COPI-mediated anterograde transport
R-DME-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-DME-8873719 RAB geranylgeranylation
R-DME-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Submitted name:
FI01544pImported
Submitted name:
Rab1Imported
Gene namesi
Name:Rab1Imported
Synonyms:AAF55873Imported, dar6Imported, Dm Rab1Imported, Dmel\CG3320Imported, DmRab1Imported, DRAB1Imported, DRab1Imported, dRab1Imported, drab1Imported, O18332Imported, rab1Imported, Rab1-RAImported, RAB1aImported, Rab1aImported
ORF Names:CG3320Imported, Dmel_CG3320Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0285937 Rab1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0016700

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
tempQ9W5014EBI-89408,EBI-119928

Protein-protein interaction databases

DIPiDIP-51950N
STRINGi7227.FBpp0083503

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0084 Eukaryota
ENOG410XQN5 LUCA
GeneTreeiENSGT00900000140786
HOGENOMiHOG000208217
KOiK07874
OMAiVTDNDTF
OrthoDBiEOG091G0LA6

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit

Sequencei

Sequence statusi: Complete.

O18332-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSVNPEYDY LFKLLLIGDS GVGKSCLLLR FADDTYTESY ISTIGVDFKI
60 70 80 90 100
RTIELDGKTI KLQIWDTAGQ ERFRTITSSY YRGAHGIIVV YDCTDQESFN
110 120 130 140 150
NVKQWLEEIE RYACENVNKL LVGNKSDLTT KKVVDHTTAA EYAAQLGIPF
160 170 180 190 200
LETSAKSATN VEQAFMTMAA EIKNRVGPPS SATDNASKVK IDQGRPVENT

KSGCC
Length:205
Mass (Da):22,763
Last modified:January 1, 1998 - v1
Checksum:i9CE2691205FAE343
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAF55873.1
BT046126 mRNA Translation: ACI46514.1
D84312 mRNA Translation: BAA21705.1
RefSeqiNP_732610.1, NM_169953.3
UniGeneiDm.2386

Genome annotation databases

EnsemblMetazoaiFBtr0084104; FBpp0083503; FBgn0285937
GeneIDi42524
KEGGidme:Dmel_CG3320
UCSCiCG3320-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiO18332_DROME
AccessioniPrimary (citable) accession number: O18332
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: June 20, 2018
This is version 157 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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