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Protein

Amino acid transporter

Gene

glt-5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

SymportUniRule annotation, Transport

Enzyme and pathway databases

ReactomeiR-CEL-210500. Glutamate Neurotransmitter Release Cycle.
R-CEL-425393. Transport of inorganic cations/anions and amino acids/oligopeptides.

Names & Taxonomyi

Protein namesi
Recommended name:
Amino acid transporterUniRule annotation
Gene namesi
Name:glt-5Imported
ORF Names:CELE_Y53C12A.2Imported, Y53C12A.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiY53C12A.2; CE14886; WBGene00001623; glt-5.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4222HelicalUniRule annotationAdd
BLAST
Transmembranei62 – 8221HelicalUniRule annotationAdd
BLAST
Transmembranei94 – 11623HelicalUniRule annotationAdd
BLAST
Transmembranei189 – 20719HelicalUniRule annotationAdd
BLAST
Transmembranei219 – 24224HelicalUniRule annotationAdd
BLAST
Transmembranei262 – 28928HelicalUniRule annotationAdd
BLAST
Transmembranei369 – 39123HelicalUniRule annotationAdd
BLAST
Transmembranei397 – 42327HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiO18210.

Interactioni

Protein-protein interaction databases

DIPiDIP-26370N.
MINTiMINT-1102543.
STRINGi6239.Y53C12A.2.1.

Structurei

3D structure databases

ProteinModelPortaliO18210.
SMRiO18210. Positions 21-442.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili464 – 49128Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG3787. Eukaryota.
COG1301. LUCA.
GeneTreeiENSGT00760000119117.
HOGENOMiHOG000208776.
InParanoidiO18210.
OMAiVAKSHEM.
OrthoDBiEOG7RV9G2.
PhylomeDBiO18210.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiIPR001991. Na-dicarboxylate_symporter.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 2 hits.

Sequencei

Sequence statusi: Complete.

O18210-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIASKKSVS RWTSWLTKNM LLLMTMAGIV MGVIIGGVLR TADPSPDVIR
60 70 80 90 100
YVGFPGELFM NMLKAMVLPL IAASIVSGLS QLDGKTSGRL GSRAVMYYAI
110 120 130 140 150
TTTHAVILGI IVVSIIQPGD PTIKQKMGYD KEGEAANVSA AQKFLDLFRN
160 170 180 190 200
AFPENIMRAT FSQVQTNYIN QTHSNGATHE VLHTGYVDGM NVLGIIVFCI
210 220 230 240 250
VMGLVVSRIG EEAKALANLF HALDVVITRM VMLIMWLGPI GIPSLIAQKM
260 270 280 290 300
LEVSDLWLTA RMLGLFVFTV ILGLAIQAFI TLPLIYFIGT RHNPYTFLKG
310 320 330 340 350
LGQAIMTALG TSSSAASLPV TFRCLNKLGI DPRVTKFVLP VGAMVNMDGT
360 370 380 390 400
ALYEATASIF IAQMNGLELS IGQIVTVSIT ATLASIGAAS IPSAGLVTML
410 420 430 440 450
IVLTALGLPA NDISLILAVD WFLDRLRTSV NVIGDALGCG FVHHICADHL
460 470 480 490
NADVAEAEKN HAVVEAHGVN FDELEKECEQ ENNNQKQIEQ V
Length:491
Mass (Da):52,818
Last modified:January 1, 1998 - v1
Checksum:iDC5198C17C24D150
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAB16485.1.
PIRiT27128.
RefSeqiNP_496094.1. NM_063693.4.
UniGeneiCel.17547.

Genome annotation databases

EnsemblMetazoaiY53C12A.2; Y53C12A.2; WBGene00001623.
GeneIDi174530.
KEGGicel:CELE_Y53C12A.2.
UCSCiY53C12A.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA. Translation: CAB16485.1.
PIRiT27128.
RefSeqiNP_496094.1. NM_063693.4.
UniGeneiCel.17547.

3D structure databases

ProteinModelPortaliO18210.
SMRiO18210. Positions 21-442.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-26370N.
MINTiMINT-1102543.
STRINGi6239.Y53C12A.2.1.

Proteomic databases

PaxDbiO18210.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY53C12A.2; Y53C12A.2; WBGene00001623.
GeneIDi174530.
KEGGicel:CELE_Y53C12A.2.
UCSCiY53C12A.2.1. c. elegans.

Organism-specific databases

CTDi174530.
WormBaseiY53C12A.2; CE14886; WBGene00001623; glt-5.

Phylogenomic databases

eggNOGiKOG3787. Eukaryota.
COG1301. LUCA.
GeneTreeiENSGT00760000119117.
HOGENOMiHOG000208776.
InParanoidiO18210.
OMAiVAKSHEM.
OrthoDBiEOG7RV9G2.
PhylomeDBiO18210.

Enzyme and pathway databases

ReactomeiR-CEL-210500. Glutamate Neurotransmitter Release Cycle.
R-CEL-425393. Transport of inorganic cations/anions and amino acids/oligopeptides.

Miscellaneous databases

NextBioi884416.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiIPR001991. Na-dicarboxylate_symporter.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiO18210_CAEEL
AccessioniPrimary (citable) accession number: O18210
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 11, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.