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Protein
Submitted name:

DeHydrogenases, Short chain

Gene

dhs-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-CEL-193144. Estrogen biosynthesis.
R-CEL-5365859. RA biosynthesis pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
DeHydrogenases, Short chainImported
Gene namesi
Name:dhs-4Imported
ORF Names:CELE_T05F1.10Imported, T05F1.10Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiT05F1.10; CE26900; WBGene00000968; dhs-4.

PTM / Processingi

Proteomic databases

EPDiO18030.
PaxDbiO18030.
PRIDEiO18030.

Expressioni

Gene expression databases

BgeeiWBGene00000968.

Interactioni

Protein-protein interaction databases

STRINGi6239.T05F1.10.

Structurei

3D structure databases

ProteinModelPortaliO18030.
SMRiO18030. Positions 35-271.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IP7K. Eukaryota.
COG0300. LUCA.
GeneTreeiENSGT00540000069900.
InParanoidiO18030.
OMAiAHSYEVN.
OrthoDBiEOG091G0825.
PhylomeDBiO18030.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

O18030-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDIILEIVI LLFNLLIQNL ISLIKYALPY SLLPKKDLYR KKVLITGAGN
60 70 80 90 100
GLGKLLAQKF AARGATLILW DINLQSVDEL KNEIRGNQGE AHSYEVNLCD
110 120 130 140 150
PGKIAQVGQQ VINDIGKVDI LVNNAGIATA KMILDSSENE INRSFDVNVK
160 170 180 190 200
AHFYTVQQFL PAMLKDNNGH IVTIASAAGK MGSSGLADYS STKHAAVGFH
210 220 230 240 250
DSLVAEIMES EKNGVKTTLV CPYYVHTSMF DATGAATRFP WIFPILDTDY
260 270 280 290 300
VVQKIFEAIE TEQEFLVTPR AFYLVFAGIQ ILPYKAQAMV AQFFGLVQNL

ERFHK
Length:305
Mass (Da):33,821
Last modified:June 1, 2001 - v2
Checksum:i4A609F6C837C5AC6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB04694.2.
PIRiT24540.
RefSeqiNP_492563.1. NM_060162.3.
UniGeneiCel.16810.

Genome annotation databases

EnsemblMetazoaiT05F1.10; T05F1.10; WBGene00000968.
GeneIDi172810.
KEGGicel:CELE_T05F1.10.
UCSCiT05F1.10. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CAB04694.2.
PIRiT24540.
RefSeqiNP_492563.1. NM_060162.3.
UniGeneiCel.16810.

3D structure databases

ProteinModelPortaliO18030.
SMRiO18030. Positions 35-271.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T05F1.10.

Proteomic databases

EPDiO18030.
PaxDbiO18030.
PRIDEiO18030.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT05F1.10; T05F1.10; WBGene00000968.
GeneIDi172810.
KEGGicel:CELE_T05F1.10.
UCSCiT05F1.10. c. elegans.

Organism-specific databases

CTDi172810.
WormBaseiT05F1.10; CE26900; WBGene00000968; dhs-4.

Phylogenomic databases

eggNOGiENOG410IP7K. Eukaryota.
COG0300. LUCA.
GeneTreeiENSGT00540000069900.
InParanoidiO18030.
OMAiAHSYEVN.
OrthoDBiEOG091G0825.
PhylomeDBiO18030.

Enzyme and pathway databases

ReactomeiR-CEL-193144. Estrogen biosynthesis.
R-CEL-5365859. RA biosynthesis pathway.

Gene expression databases

BgeeiWBGene00000968.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO18030_CAEEL
AccessioniPrimary (citable) accession number: O18030
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 124 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.