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Protein
Submitted name:

AIP1 (Actin Interacting Protein 1) Like

Gene

aipl-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • actin filament depolymerization Source: GO_Central
  • actin filament organization Source: WormBase
  • locomotion Source: GO_Central
  • positive regulation of actin filament depolymerization Source: GO_Central
  • regulation of protein localization Source: WormBase
  • sarcomere organization Source: GO_Central

Enzyme and pathway databases

ReactomeiR-CEL-114608 Platelet degranulation
SignaLinkiO17939

Names & Taxonomyi

Protein namesi
Submitted name:
AIP1 (Actin Interacting Protein 1) LikeImported
Gene namesi
Name:aipl-1Imported
ORF Names:CELE_K08F9.2Imported, K08F9.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiK08F9.2 ; CE11944 ; WBGene00010685 ; aipl-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiO17939
PaxDbiO17939
PeptideAtlasiO17939

Expressioni

Gene expression databases

BgeeiWBGene00010685

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6239.K08F9.2.2

Structurei

3D structure databases

ProteinModelPortaliO17939
SMRiO17939
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 600WD_REPEATS_REGIONInterPro annotationAdd BLAST546
Repeati55 – 96WDPROSITE-ProRule annotationAdd BLAST42
Repeati186 – 218WDPROSITE-ProRule annotationAdd BLAST33
Repeati233 – 274WDPROSITE-ProRule annotationAdd BLAST42
Repeati318 – 359WDPROSITE-ProRule annotationAdd BLAST42
Repeati521 – 555WDPROSITE-ProRule annotationAdd BLAST35
Repeati580 – 600WDPROSITE-ProRule annotationAdd BLAST21

Keywords - Domaini

RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0318 Eukaryota
ENOG410XQN1 LUCA
GeneTreeiENSGT00390000009416
HOGENOMiHOG000162559
InParanoidiO17939
OMAiHSSHREH
OrthoDBiEOG091G03SZ
PhylomeDBiO17939

Family and domain databases

Gene3Di2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR024977 Apc4_WD40_dom
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF12894 ANAPC4_WD40, 1 hit
PF00400 WD40, 5 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 11 hits
SUPFAMiSSF50978 SSF50978, 2 hits
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 3 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O17939-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEFSQTAVF PSLPRAARGV PVILGSSPAG DKILYCNGNS VFTIPIDSLN
60 70 80 90 100
SADIYTEHAH QTTVAKISPT GFYCASGDTQ GNIRIWDTTQ STHILKHTIP
110 120 130 140 150
VFSGPVKDIA WDSESKRIAA VGEGKERFGH VFLLDTTTSN GSLTGQSRTM
160 170 180 190 200
NSVDFKPTRP FRIISGSDDN TVAIFEGPPF KFKHTFDHHK KFVQSTRYNN
210 220 230 240 250
DGSLFASTGS DGTVVLYNGV DGEKVGVLED AKGVAHTGSI FALAWSPDQS
260 270 280 290 300
RIATASADKS VKIWDVSARK LERTIVMGSK IEDQQLGIVW TKSALITVSV
310 320 330 340 350
SGFLNFLNPD DGSVEKIRQG HNKAITALSK SSDGKFLFSA DAEGHITTWE
360 370 380 390 400
ISSGTSSRKS PHTTMITGAQ TSSNGDLFTV GWDDQLKITD GSGDTKSFKL
410 420 430 440 450
PSQPCGLEVS DDLAIVACYK HVVVLSRGTP TENPIEFHST CVAFCAEKSL
460 470 480 490 500
VAVGGKDAKV HVYKLNGDGR LEELKKIEHS AEITAVSFSD DGEYLAVTDL
510 520 530 540 550
ARKVIPYSVS TDFSVTSPNS WTFHTSKVLT VAWSPDNQRL ATGSIDTSVI
560 570 580 590 600
IWDMKKPGEH PVIIKGAHPM SSVNVVRWLD ETTVVSAGQD SNIKFWNVPL
Length:600
Mass (Da):64,887
Last modified:January 1, 1998 - v1
Checksum:i5637D3F823127600
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CAB03187.1
PIRiT23497
RefSeqiNP_506733.1, NM_074332.4
UniGeneiCel.3069

Genome annotation databases

EnsemblMetazoaiK08F9.2.1; K08F9.2.1; WBGene00010685
K08F9.2.2; K08F9.2.2; WBGene00010685
GeneIDi180022
KEGGicel:CELE_K08F9.2
UCSCiK08F9.2.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiO17939_CAEEL
AccessioniPrimary (citable) accession number: O17939
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health