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Protein
Submitted name:

AIP1 (Actin Interacting Protein 1) Like

Gene

aipl-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • actin filament depolymerization Source: GO_Central
  • actin filament organization Source: WormBase
  • locomotion Source: GO_Central
  • positive regulation of actin filament depolymerization Source: GO_Central
  • regulation of protein localization Source: WormBase
  • sarcomere organization Source: GO_Central

Enzyme and pathway databases

ReactomeiR-CEL-114608. Platelet degranulation.
SignaLinkiO17939.

Names & Taxonomyi

Protein namesi
Submitted name:
AIP1 (Actin Interacting Protein 1) LikeImported
Gene namesi
Name:aipl-1Imported
ORF Names:CELE_K08F9.2Imported, K08F9.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiK08F9.2; CE11944; WBGene00010685; aipl-1.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

EPDiO17939.
PaxDbiO17939.
PeptideAtlasiO17939.

Expressioni

Gene expression databases

BgeeiWBGene00010685.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6239.K08F9.2.2.

Structurei

3D structure databases

ProteinModelPortaliO17939.
SMRiO17939.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 600WD_REPEATS_REGIONInterPro annotationAdd BLAST546
Repeati55 – 96WDPROSITE-ProRule annotationAdd BLAST42
Repeati186 – 218WDPROSITE-ProRule annotationAdd BLAST33
Repeati233 – 274WDPROSITE-ProRule annotationAdd BLAST42
Repeati318 – 359WDPROSITE-ProRule annotationAdd BLAST42
Repeati521 – 555WDPROSITE-ProRule annotationAdd BLAST35
Repeati580 – 600WDPROSITE-ProRule annotationAdd BLAST21

Keywords - Domaini

RepeatSAAS annotation, WD repeatPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0318. Eukaryota.
ENOG410XQN1. LUCA.
GeneTreeiENSGT00390000009416.
HOGENOMiHOG000162559.
InParanoidiO17939.
OMAiHTIPVFS.
OrthoDBiEOG091G03SZ.
PhylomeDBiO17939.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR024977. Apc4_WD40_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF12894. ANAPC4_WD40. 1 hit.
PF00400. WD40. 5 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00320. WD40. 11 hits.
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 6 hits.
PS50294. WD_REPEATS_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

O17939-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEFSQTAVF PSLPRAARGV PVILGSSPAG DKILYCNGNS VFTIPIDSLN
60 70 80 90 100
SADIYTEHAH QTTVAKISPT GFYCASGDTQ GNIRIWDTTQ STHILKHTIP
110 120 130 140 150
VFSGPVKDIA WDSESKRIAA VGEGKERFGH VFLLDTTTSN GSLTGQSRTM
160 170 180 190 200
NSVDFKPTRP FRIISGSDDN TVAIFEGPPF KFKHTFDHHK KFVQSTRYNN
210 220 230 240 250
DGSLFASTGS DGTVVLYNGV DGEKVGVLED AKGVAHTGSI FALAWSPDQS
260 270 280 290 300
RIATASADKS VKIWDVSARK LERTIVMGSK IEDQQLGIVW TKSALITVSV
310 320 330 340 350
SGFLNFLNPD DGSVEKIRQG HNKAITALSK SSDGKFLFSA DAEGHITTWE
360 370 380 390 400
ISSGTSSRKS PHTTMITGAQ TSSNGDLFTV GWDDQLKITD GSGDTKSFKL
410 420 430 440 450
PSQPCGLEVS DDLAIVACYK HVVVLSRGTP TENPIEFHST CVAFCAEKSL
460 470 480 490 500
VAVGGKDAKV HVYKLNGDGR LEELKKIEHS AEITAVSFSD DGEYLAVTDL
510 520 530 540 550
ARKVIPYSVS TDFSVTSPNS WTFHTSKVLT VAWSPDNQRL ATGSIDTSVI
560 570 580 590 600
IWDMKKPGEH PVIIKGAHPM SSVNVVRWLD ETTVVSAGQD SNIKFWNVPL
Length:600
Mass (Da):64,887
Last modified:January 1, 1998 - v1
Checksum:i5637D3F823127600
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB03187.1.
PIRiT23497.
RefSeqiNP_506733.1. NM_074332.4.
UniGeneiCel.3069.

Genome annotation databases

EnsemblMetazoaiK08F9.2; K08F9.2; WBGene00010685.
GeneIDi180022.
KEGGicel:CELE_K08F9.2.
UCSCiK08F9.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB03187.1.
PIRiT23497.
RefSeqiNP_506733.1. NM_074332.4.
UniGeneiCel.3069.

3D structure databases

ProteinModelPortaliO17939.
SMRiO17939.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.K08F9.2.2.

Proteomic databases

EPDiO17939.
PaxDbiO17939.
PeptideAtlasiO17939.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK08F9.2; K08F9.2; WBGene00010685.
GeneIDi180022.
KEGGicel:CELE_K08F9.2.
UCSCiK08F9.2.1. c. elegans.

Organism-specific databases

CTDi180022.
WormBaseiK08F9.2; CE11944; WBGene00010685; aipl-1.

Phylogenomic databases

eggNOGiKOG0318. Eukaryota.
ENOG410XQN1. LUCA.
GeneTreeiENSGT00390000009416.
HOGENOMiHOG000162559.
InParanoidiO17939.
OMAiHTIPVFS.
OrthoDBiEOG091G03SZ.
PhylomeDBiO17939.

Enzyme and pathway databases

ReactomeiR-CEL-114608. Platelet degranulation.
SignaLinkiO17939.

Gene expression databases

BgeeiWBGene00010685.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiView protein in InterPro
IPR024977. Apc4_WD40_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
PfamiView protein in Pfam
PF12894. ANAPC4_WD40. 1 hit.
PF00400. WD40. 5 hits.
PRINTSiPR00320. GPROTEINBRPT.
SMARTiView protein in SMART
SM00320. WD40. 11 hits.
SUPFAMiSSF50978. SSF50978. 2 hits.
PROSITEiView protein in PROSITE
PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 6 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO17939_CAEEL
AccessioniPrimary (citable) accession number: O17939
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: June 7, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.