Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nuclear hormone receptor family member nhr-53

Gene

nhr-53

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi20 – 95Nuclear receptorPROSITE-ProRule annotationAdd BLAST76
Zinc fingeri23 – 43NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri59 – 83NR C4-typePROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-53
Gene namesi
Name:nhr-53
ORF Names:K06B4.11
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiK06B4.11; CE27770; WBGene00003643; nhr-53.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000537871 – 364Nuclear hormone receptor family member nhr-53Add BLAST364

Proteomic databases

PaxDbiO17933.

Expressioni

Gene expression databases

BgeeiWBGene00003643.

Interactioni

Protein-protein interaction databases

BioGridi45046. 4 interactors.
IntActiO17933. 3 interactors.
MINTiMINT-1058766.
STRINGi6239.K06B4.11.

Structurei

3D structure databases

ProteinModelPortaliO17933.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated
Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri23 – 43NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri59 – 83NR C4-typePROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00530000064422.
HOGENOMiHOG000237300.
InParanoidiO17933.
OMAiFLCEAFP.
OrthoDBiEOG091G0BF9.
PhylomeDBiO17933.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17933-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSPTHLLNN FESSSSQGPP SYCLICCEVA DGHHFGAAAC RACAAFFRRT
60 70 80 90 100
VQLNKVHDCP KNGQCFILSN VRNMCRACRY EKCLEVGMQR SSVQQKRDQL
110 120 130 140 150
GRRDGLPTNR EEPVLDTMRR AYEKLLVVRK KVHNRQENQL PRAISFNELQ
160 170 180 190 200
VVYQNEMTVI YQFLCEAFPE YSELLPDTKR SLFKNFFLPF TLLESSYYGY
210 220 230 240 250
LTKQENVMLI PSGDYVDLAH LESYFNNNHH TFSQKDTISM FAQQFRMLHT
260 270 280 290 300
SITVPLSAEN VDVNEFLALA AIILWESDLE VEADRKNVQE EAVKIKSAII
310 320 330 340 350
KDLLFHYQSI NVYADVAMRL GAVLSILPSI QRASHRFHEY MEIKNLLNLY
360
ALPKNLYDMF SPTS
Length:364
Mass (Da):41,980
Last modified:January 31, 2002 - v3
Checksum:i6E6016AAA5AC9F2E
GO

Sequence cautioni

The sequence AAG15147 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAG15148 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF273798 mRNA. Translation: AAG15147.1. Different initiation.
AF273799 mRNA. Translation: AAG15148.1. Different initiation.
Z83233 Genomic DNA. Translation: CAB05768.2.
PIRiT23372.
RefSeqiNP_741644.1. NM_171556.4.
UniGeneiCel.19468.

Genome annotation databases

EnsemblMetazoaiK06B4.11; K06B4.11; WBGene00003643.
GeneIDi180053.
KEGGicel:CELE_K06B4.11.
UCSCiK06B4.11. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF273798 mRNA. Translation: AAG15147.1. Different initiation.
AF273799 mRNA. Translation: AAG15148.1. Different initiation.
Z83233 Genomic DNA. Translation: CAB05768.2.
PIRiT23372.
RefSeqiNP_741644.1. NM_171556.4.
UniGeneiCel.19468.

3D structure databases

ProteinModelPortaliO17933.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi45046. 4 interactors.
IntActiO17933. 3 interactors.
MINTiMINT-1058766.
STRINGi6239.K06B4.11.

Proteomic databases

PaxDbiO17933.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK06B4.11; K06B4.11; WBGene00003643.
GeneIDi180053.
KEGGicel:CELE_K06B4.11.
UCSCiK06B4.11. c. elegans.

Organism-specific databases

CTDi180053.
WormBaseiK06B4.11; CE27770; WBGene00003643; nhr-53.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00530000064422.
HOGENOMiHOG000237300.
InParanoidiO17933.
OMAiFLCEAFP.
OrthoDBiEOG091G0BF9.
PhylomeDBiO17933.

Miscellaneous databases

PROiO17933.

Gene expression databases

BgeeiWBGene00003643.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNHR53_CAEEL
AccessioniPrimary (citable) accession number: O17933
Secondary accession number(s): Q9GTG0, Q9GTG1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 31, 2002
Last modified: November 2, 2016
This is version 123 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.