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Protein

Nuclear hormone receptor family member nhr-51

Gene

nhr-51

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi2 – 7776Nuclear receptorPROSITE-ProRule annotationAdd
BLAST
Zinc fingeri5 – 2521NR C4-typePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri41 – 6020NR C4-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-51
Gene namesi
Name:nhr-51
ORF Names:K06B4.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiK06B4.1; CE35582; WBGene00003641; nhr-51.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 371371Nuclear hormone receptor family member nhr-51PRO_0000223577Add
BLAST

Proteomic databases

PaxDbiO17927.

Expressioni

Gene expression databases

ExpressionAtlasiO17927. baseline.

Interactioni

Protein-protein interaction databases

BioGridi45045. 2 interactions.
DIPiDIP-25072N.
IntActiO17927. 2 interactions.
MINTiMINT-1072256.

Structurei

3D structure databases

ProteinModelPortaliO17927.
SMRiO17927. Positions 3-337.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated
Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri5 – 2521NR C4-typePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri41 – 6020NR C4-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410K7C1. Eukaryota.
ENOG4110MJ8. LUCA.
GeneTreeiENSGT00530000064378.
HOGENOMiHOG000015902.
InParanoidiO17927.
OMAiAHEWAFL.
OrthoDBiEOG7R2BPW.
PhylomeDBiO17927.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17927-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKNCLICHR KAAGQHYGVL SCFACKMFFH RMVVENLHYC CQKFNKCYEK
60 70 80 90 100
FIILPKCKAC RYQKCLEMGM QAFPRRVKSF EESMDLKIQR MLMNLSEMDE
110 120 130 140 150
QRHWRMLNSY SIEDPSLGDV LVDSNVMKIM RKPSNQKVTA HEWAFLDVYS
160 170 180 190 200
RISHFSNFEF MNNISFADRK LIFSFNCLRT GVFHGSMRTL REQRDCLLTP
210 220 230 240 250
SGEDVYPDAV HNLFKDSPGL LNRTCCLLVS KLIELKVTNE EYQLLSLIFF
260 270 280 290 300
CNPTISHNLS DFARNTLASH QIKYSSALFR HLQITNPGTA PVRFQELISL
310 320 330 340 350
VHVINRVTND MQHVSMMFQC MIPSFKFKQL VTDTFVDCGV VQKKSNVKIL
360 370
NEKPCADSSQ DFIFHKNKFI H
Length:371
Mass (Da):43,306
Last modified:July 5, 2004 - v3
Checksum:i4C8F3CA85C004ACE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83233 Genomic DNA. Translation: CAB05760.3.
PIRiT23364.
RefSeqiNP_506898.2. NM_074497.4.
UniGeneiCel.38844.

Genome annotation databases

EnsemblMetazoaiK06B4.1; K06B4.1; WBGene00003641.
GeneIDi180052.
KEGGicel:CELE_K06B4.1.
UCSCiK06B4.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83233 Genomic DNA. Translation: CAB05760.3.
PIRiT23364.
RefSeqiNP_506898.2. NM_074497.4.
UniGeneiCel.38844.

3D structure databases

ProteinModelPortaliO17927.
SMRiO17927. Positions 3-337.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi45045. 2 interactions.
DIPiDIP-25072N.
IntActiO17927. 2 interactions.
MINTiMINT-1072256.

Proteomic databases

PaxDbiO17927.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK06B4.1; K06B4.1; WBGene00003641.
GeneIDi180052.
KEGGicel:CELE_K06B4.1.
UCSCiK06B4.1. c. elegans.

Organism-specific databases

CTDi180052.
WormBaseiK06B4.1; CE35582; WBGene00003641; nhr-51.

Phylogenomic databases

eggNOGiENOG410K7C1. Eukaryota.
ENOG4110MJ8. LUCA.
GeneTreeiENSGT00530000064378.
HOGENOMiHOG000015902.
InParanoidiO17927.
OMAiAHEWAFL.
OrthoDBiEOG7R2BPW.
PhylomeDBiO17927.

Miscellaneous databases

NextBioi907900.
PROiO17927.

Gene expression databases

ExpressionAtlasiO17927. baseline.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiNHR51_CAEEL
AccessioniPrimary (citable) accession number: O17927
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: November 11, 2015
This is version 109 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.