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Protein
Submitted name:

FERM domain (Protein4.1-ezrin-radixin-moesin) family

Gene

frm-3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • cytoskeletal protein binding Source: InterPro
  • GABA receptor binding Source: WormBase

GO - Biological processi

  • gamma-aminobutyric acid receptor clustering Source: WormBase

Enzyme and pathway databases

ReactomeiR-CEL-399955. SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion.

Names & Taxonomyi

Protein namesi
Submitted name:
FERM domain (Protein4.1-ezrin-radixin-moesin) familyImported
Gene namesi
Name:frm-3Imported
ORF Names:CELE_H05G16.1Imported, H05G16.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiH05G16.1a; CE43269; WBGene00001490; frm-3.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

EPDiO17905.
PaxDbiO17905.
PeptideAtlasiO17905.

Expressioni

Gene expression databases

BgeeiWBGene00001490.

Interactioni

GO - Molecular functioni

  • cytoskeletal protein binding Source: InterPro
  • GABA receptor binding Source: WormBase

Protein-protein interaction databases

IntActiO17905. 1 interactor.
STRINGi6239.H05G16.1.

Structurei

3D structure databases

ProteinModelPortaliO17905.
SMRiO17905.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 309FERMInterPro annotationAdd BLAST285

Phylogenomic databases

eggNOGiKOG3531. Eukaryota.
ENOG410XP7Q. LUCA.
GeneTreeiENSGT00890000139342.
HOGENOMiHOG000021058.
InParanoidiO17905.
KOiK06082.
OMAiCIKVRML.
OrthoDBiEOG091G015W.

Family and domain databases

CDDicd14473. FERM_B-lobe. 1 hit.
Gene3Di1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
InterProiView protein in InterPro
IPR019749. Band_41_domain.
IPR000798. Ez/rad/moesin-like.
IPR014847. FERM-adjacent.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR019747. FERM_CS.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR018980. FERM_PH-like_C.
IPR011993. PH_dom-like.
IPR029071. Ubiquitin-rel_dom.
PfamiView protein in Pfam
PF08736. FA. 1 hit.
PF09380. FERM_C. 1 hit.
PF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
PRINTSiPR00935. BAND41.
PR00661. ERMFAMILY.
SMARTiView protein in SMART
SM00295. B41. 1 hit.
SM01195. FA. 1 hit.
SM01196. FERM_C. 1 hit.
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiView protein in PROSITE
PS00660. FERM_1. 1 hit.
PS50057. FERM_3. 1 hit.

Sequencei

Sequence statusi: Complete.

O17905-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNIPRGVGA PPPPGMNSSK RGRLVCIKVR MLDDTVAVFH LGHKAIGQTL
60 70 80 90 100
LDEVCRHLNL LECDYFGLSF IDINGNHCWL DREKTILRQI TNGSTDAKFY
110 120 130 140 150
FVVKFYTPNP IDLEEEYTRY LFTMQIKRDL ALGELHCSDN TASLLSAYLV
160 170 180 190 200
QSECGDFSSE DYPDATYLSH TRFVPNQTLE FQKKVMDNHR NFIGMTPGES
210 220 230 240 250
DLAMLEVARR CDFYGVKLHA AKDIDGNDAA LSVMHLGIKV FRQLQLDTTF
260 270 280 290 300
SWARIRKLSF KRKKLLVKLH PDSYQYLKET VEFSFETRDE CKNFWKKCVE
310 320 330 340 350
HHAFFRCVQA EEPKKETRFF ISKGSSFRYH GRTQKQLIDY VREHHKRREP
360 370 380 390 400
FTRPLRSAAS TRKGTYSSTY GLVTDRPTKH RNGSVYEPNQ TDPYNKHQNT
410 420 430 440 450
HSSMPHIAHI SSQPADHSFS GTLDARVGKS VTRDPSTSVT QHRLRQLKRS
460 470 480 490 500
ERCISDVDTV ERPQRSSCRP VSHAINISST SSKEQPDLSV SLPNVLSDDL
510 520 530 540 550
QMVCKEIEIE QNDPPKSVSG DNFQQRRSSR DYDNVSEDSY RLSDHERSTR
560 570 580 590 600
SEVGVGSKFA AATIFNSTFV ARKPGSNVVK RVVAHTKSTP NSTDDEEGAL
610 620 630 640 650
KSASEYQTFR HIKEYPFARN ANIVPIEIDG PNVDLSARRS PAATTTTTRT
660 670 680 690 700
YANTTTTVTT TSKVLTSSGA VLMKPKVISN DHEPSSGTHS SRVSPESGTY
710 720 730 740 750
GALGPLPGRV ITKENMMITP EGFKEKKAKP NPPPKPSFPV QAVHSETEVV
760 770 780 790 800
REIKTERASS HPLVHMQEEI PFSRAPLKFE DKKERKSSLS RPALISVQSE
810 820 830 840 850
DNPDVQKCHL FNSDIPYTLT MRNVENTQSL PYSSFKDVST AKKQGYESNS
860 870 880 890 900
LKRVSKSPEF KRRKSLDLVP RKRLPSPGNF SAQDHTISPT TPDSDVLEYL
910 920 930 940 950
LRRRSLLGDK SVIKTKSKRT DPRRQTQPVR FDLPPSPCSP TAGGSTPFIS
960 970 980 990 1000
ILNDDLFDEC VSESRSLHED MDRLDKTTPH NQSISSFMSQ KSRRDSEDSD
1010 1020 1030 1040 1050
VMPPPPEEIL NKAMISSSRP APPPPPPKSL AAAVKVAEMK AAAAGKIYYS
1060 1070 1080 1090
GSSRTGKITD SPPFIDDSPK NSSASDAPSV PSPQKNCFSD F
Length:1,091
Mass (Da):122,458
Last modified:December 16, 2008 - v2
Checksum:i59BEEDCFFACD9D9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAB10024.2.
RefSeqiNP_509934.2. NM_077533.3.
UniGeneiCel.815.

Genome annotation databases

EnsemblMetazoaiH05G16.1; H05G16.1; WBGene00001490.
GeneIDi186110.
KEGGicel:CELE_H05G16.1.
UCSCiH05G16.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiO17905_CAEEL
AccessioniPrimary (citable) accession number: O17905
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: December 16, 2008
Last modified: August 30, 2017
This is version 134 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported