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Protein
Submitted name:

TransKeTolase homolog

Gene

tkt-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-CEL-163754. Insulin effects increased synthesis of Xylulose-5-Phosphate.
R-CEL-71336. Pentose phosphate pathway (hexose monophosphate shunt).

Names & Taxonomyi

Protein namesi
Submitted name:
TransKeTolase homologImported
Gene namesi
Name:tkt-1Imported
ORF Names:CELE_F01G10.1Imported, F01G10.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF01G10.1; CE09163; WBGene00008506; tkt-1.

PTM / Processingi

Proteomic databases

EPDiO17759.
PaxDbiO17759.
PeptideAtlasiO17759.

Expressioni

Gene expression databases

BgeeiWBGene00008506.

Interactioni

Protein-protein interaction databases

DIPiDIP-25606N.
IntActiO17759. 1 interactor.
MINTiMINT-1109227.
STRINGi6239.F01G10.1.2.

Structurei

3D structure databases

ProteinModelPortaliO17759.
SMRiO17759.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini313 – 477Transket_pyrInterPro annotationAdd BLAST165

Phylogenomic databases

eggNOGiKOG0523. Eukaryota.
COG0021. LUCA.
GeneTreeiENSGT00390000005240.
HOGENOMiHOG000243868.
InParanoidiO17759.
KOiK00615.
OMAiRALANCI.
OrthoDBiEOG091G03M5.
PhylomeDBiO17759.

Family and domain databases

Gene3Di3.40.50.920. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR029061. THDP-binding.
IPR009014. Transketo_C/PFOR_II.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR033248. Transketolase_C.
IPR033247. Transketolase_fam.
IPR005474. Transketolase_N.
[Graphical view]
PANTHERiPTHR11624. PTHR11624. 1 hit.
PfamiPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
PF00456. Transketolase_N. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
SSF52922. SSF52922. 1 hit.
PROSITEiPS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17759-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVSEQLRND LEDAANRMRI SSIEMTCASK SGHPTSSTSA AEIMSTLFFS
60 70 80 90 100
EMKYDVAEPK SASADRFVLS KGHACPILYA AWEEAGLLSH EQVLSLRKID
110 120 130 140 150
SDIEGHPTPR LNFIDVATGS LGQGLGVATG MAYVGKYIDK ASYRVFCLLG
160 170 180 190 200
DGESAEGSVW EAAAFASIYK LDNLVAIVDV NRLGQSQATS LGHDVETYKA
210 220 230 240 250
RFAAFGFNAI IVNGHNVDEL LAAYETARST KGKPTAIIAK TLKGKGIEGI
260 270 280 290 300
ENEDNWHGKP VPEGTVNAIK ARFHGSQKGK LVAQKPINDA PAIDLHVGSI
310 320 330 340 350
KMAAPEYKKG DKVATRAAYG TALAKLGDAS PRVIGLDGDT KNSTFSDKLL
360 370 380 390 400
KKHPDQFIEC FIAEQNLVGV AVGAQCRDRT IPFTSTFAAF FTRATDQIRM
410 420 430 440 450
AAVSFANLKC VGSHVGVSIG EDGPSQMALE DLAIFRTIPG ATVFYPTDAV
460 470 480 490 500
SAERATELAA NTKGVVFIRT GRPALPVLYD NEEPFHIGQA KVVKQSAQDK
510 520 530 540 550
IVLVGSGVTL YESLKAAEEL EKEGIHATVI DPFTIKPLDG KTIAEHALKV
560 570 580 590 600
GGRVVTTEDH YAAGGIGEAV SAALADYPTI RVRSLNVKEV PRSGPPDALV
610
DMYGISARHI VAAVKNFQ
Length:618
Mass (Da):66,011
Last modified:January 1, 1998 - v1
Checksum:i74B13D0C3AC5C8E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAB02889.1.
PIRiT20473.
RefSeqiNP_501878.1. NM_069477.3.
UniGeneiCel.8781.

Genome annotation databases

EnsemblMetazoaiF01G10.1.1; F01G10.1.1; WBGene00008506.
F01G10.1.2; F01G10.1.2; WBGene00008506.
GeneIDi177906.
KEGGicel:CELE_F01G10.1.
UCSCiF01G10.1.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAB02889.1.
PIRiT20473.
RefSeqiNP_501878.1. NM_069477.3.
UniGeneiCel.8781.

3D structure databases

ProteinModelPortaliO17759.
SMRiO17759.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-25606N.
IntActiO17759. 1 interactor.
MINTiMINT-1109227.
STRINGi6239.F01G10.1.2.

Proteomic databases

EPDiO17759.
PaxDbiO17759.
PeptideAtlasiO17759.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiF01G10.1.1; F01G10.1.1; WBGene00008506.
F01G10.1.2; F01G10.1.2; WBGene00008506.
GeneIDi177906.
KEGGicel:CELE_F01G10.1.
UCSCiF01G10.1.1. c. elegans.

Organism-specific databases

CTDi177906.
WormBaseiF01G10.1; CE09163; WBGene00008506; tkt-1.

Phylogenomic databases

eggNOGiKOG0523. Eukaryota.
COG0021. LUCA.
GeneTreeiENSGT00390000005240.
HOGENOMiHOG000243868.
InParanoidiO17759.
KOiK00615.
OMAiRALANCI.
OrthoDBiEOG091G03M5.
PhylomeDBiO17759.

Enzyme and pathway databases

ReactomeiR-CEL-163754. Insulin effects increased synthesis of Xylulose-5-Phosphate.
R-CEL-71336. Pentose phosphate pathway (hexose monophosphate shunt).

Gene expression databases

BgeeiWBGene00008506.

Family and domain databases

Gene3Di3.40.50.920. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR029061. THDP-binding.
IPR009014. Transketo_C/PFOR_II.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR033248. Transketolase_C.
IPR033247. Transketolase_fam.
IPR005474. Transketolase_N.
[Graphical view]
PANTHERiPTHR11624. PTHR11624. 1 hit.
PfamiPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
PF00456. Transketolase_N. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
SSF52922. SSF52922. 1 hit.
PROSITEiPS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO17759_CAEEL
AccessioniPrimary (citable) accession number: O17759
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 2, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.