Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nuclear hormone receptor family member nhr-169

Gene

nhr-169

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi16 – 90Nuclear receptorPROSITE-ProRule annotationAdd BLAST75
Zinc fingeri19 – 40NR C4-typePROSITE-ProRule annotationAdd BLAST22
Zinc fingeri56 – 72NR C4-typePROSITE-ProRule annotationAdd BLAST17

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-169
Gene namesi
Name:nhr-169
ORF Names:C54C8.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC54C8.1; CE36114; WBGene00008289; nhr-169.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002236011 – 356Nuclear hormone receptor family member nhr-169Add BLAST356

Proteomic databases

PaxDbiO17706.

Expressioni

Gene expression databases

BgeeiWBGene00008289.

Interactioni

Protein-protein interaction databases

IntActiO17706. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliO17706.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated
Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri19 – 40NR C4-typePROSITE-ProRule annotationAdd BLAST22
Zinc fingeri56 – 72NR C4-typePROSITE-ProRule annotationAdd BLAST17

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00390000015766.
HOGENOMiHOG000016336.
InParanoidiO17706.
PhylomeDBiO17706.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17706-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSTSLEMP FRESTDPICS VCNFSSLIAP HFGGLVCSAC ASFFRRTVAL
60 70 80 90 100
NIHYLCKKDN QCKGMRKNCR ACRFESCVKI AGMKRSLVKE RKNLNNIPLY
110 120 130 140 150
ILNRRNETGN QGVVRAFVSS NQNRLENRLS LSPLTELPIN DEMDVSKILK
160 170 180 190 200
TTPSSLLKYY VEQVSHGKQF YMNTLNIRTK EELFEIVSYQ SKVAAETCRT
210 220 230 240 250
CPGVDLLDNR DILILRKYFQ FSNIWIESTW KYWFSNDFSN DTEKFDIKLM
260 270 280 290 300
EFIGQVKSTL LISLSRLKFN IFEFTAFKAI CIWKLVYHET SRAMKIVAQE
310 320 330 340 350
HYEGVTKALI SYYQTYTLLD SMEIAIRVGE ITLLVSSVFQ MYHDMAKLYL

HMGLPF
Length:356
Mass (Da):41,272
Last modified:July 5, 2004 - v2
Checksum:iD09769DBB4B0B2D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83102 Genomic DNA. Translation: CAB05462.2.
PIRiT20200.
RefSeqiNP_493156.2. NM_060755.2.
UniGeneiCel.19068.

Genome annotation databases

EnsemblMetazoaiC54C8.1; C54C8.1; WBGene00008289.
GeneIDi183768.
KEGGicel:CELE_C54C8.1.
UCSCiC54C8.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z83102 Genomic DNA. Translation: CAB05462.2.
PIRiT20200.
RefSeqiNP_493156.2. NM_060755.2.
UniGeneiCel.19068.

3D structure databases

ProteinModelPortaliO17706.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO17706. 1 interactor.

Proteomic databases

PaxDbiO17706.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC54C8.1; C54C8.1; WBGene00008289.
GeneIDi183768.
KEGGicel:CELE_C54C8.1.
UCSCiC54C8.1. c. elegans.

Organism-specific databases

CTDi183768.
WormBaseiC54C8.1; CE36114; WBGene00008289; nhr-169.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00390000015766.
HOGENOMiHOG000016336.
InParanoidiO17706.
PhylomeDBiO17706.

Miscellaneous databases

PROiO17706.

Gene expression databases

BgeeiWBGene00008289.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNH169_CAEEL
AccessioniPrimary (citable) accession number: O17706
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 110 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.