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Protein

Nuclear hormone receptor family member nhr-164

Gene

nhr-164

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi39 – 113Nuclear receptorPROSITE-ProRule annotationAdd BLAST75
Zinc fingeri42 – 63NR C4-typePROSITE-ProRule annotationAdd BLAST22
Zinc fingeri79 – 95NR C4-typePROSITE-ProRule annotationAdd BLAST17

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-164
Gene namesi
Name:nhr-164
ORF Names:C41G6.5
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC41G6.5; CE51345; WBGene00008056; nhr-164.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002235991 – 389Nuclear hormone receptor family member nhr-164Add BLAST389

Proteomic databases

PaxDbiO17657.

Expressioni

Gene expression databases

BgeeiWBGene00008056.

Structurei

3D structure databases

ProteinModelPortaliO17657.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated
Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri42 – 63NR C4-typePROSITE-ProRule annotationAdd BLAST22
Zinc fingeri79 – 95NR C4-typePROSITE-ProRule annotationAdd BLAST17

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00390000015766.
HOGENOMiHOG000016336.
InParanoidiO17657.
OMAiDESENQY.
OrthoDBiEOG091G1OIG.
PhylomeDBiO17657.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00105. zf-C4. 1 hit.
[Graphical view]
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17657-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDYGRTRRKR LLMNGSDESE NQYAQHYVEF LETMSYTKFG VCAVCGFSCQ
60 70 80 90 100
VQYHFGGVVC GACSAFFRRT VSLNIRYLCD GDNQCKSMLK KCRACRFESC
110 120 130 140 150
VKTAGMKRSL VRRKKPTIKT TPLYIKNRET HVRNEDVLRA FIPSYTHPSP
160 170 180 190 200
ANETVEDKGK FSEKLKLSHG NILKFYINQV RYAKRKNTNI FTIKTTEDFM
210 220 230 240 250
RLVNFQRKIA DETCSSFPGV ELIDENNILI LRKYLQFSSV WIESTWTYWI
260 270 280 290 300
TNSSVSVDNM EMDKRLKELI EHVKSTLLIS LSQLKLNIFE FAAFKSFFVW
310 320 330 340 350
KLVFHKTSVA MKTIGQEHYE CVSSALKSYY QTYTSMDSTE IAVRIGEITL
360 370 380
LLSLVFVSKI DLKSKSSELN FQQIYHDMAK LYVHLGLPF
Length:389
Mass (Da):45,184
Last modified:January 1, 1998 - v1
Checksum:i20445C217941447A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z81047 Genomic DNA. Translation: CAB02829.1.
PIRiT19883.
RefSeqiNP_001309454.1. NM_001322592.1.

Genome annotation databases

EnsemblMetazoaiC41G6.5; C41G6.5; WBGene00008056.
GeneIDi183381.
KEGGicel:CELE_C41G6.5.
UCSCiC41G6.5. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z81047 Genomic DNA. Translation: CAB02829.1.
PIRiT19883.
RefSeqiNP_001309454.1. NM_001322592.1.

3D structure databases

ProteinModelPortaliO17657.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiO17657.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC41G6.5; C41G6.5; WBGene00008056.
GeneIDi183381.
KEGGicel:CELE_C41G6.5.
UCSCiC41G6.5. c. elegans.

Organism-specific databases

CTDi183381.
WormBaseiC41G6.5; CE51345; WBGene00008056; nhr-164.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00390000015766.
HOGENOMiHOG000016336.
InParanoidiO17657.
OMAiDESENQY.
OrthoDBiEOG091G1OIG.
PhylomeDBiO17657.

Miscellaneous databases

PROiO17657.

Gene expression databases

BgeeiWBGene00008056.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00105. zf-C4. 1 hit.
[Graphical view]
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNH164_CAEEL
AccessioniPrimary (citable) accession number: O17657
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.