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Protein

Nuclear hormone receptor family member nhr-100

Gene

nhr-100

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi21 – 96Nuclear receptorPROSITE-ProRule annotationAdd BLAST76
Zinc fingeri24 – 44NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri60 – 79NR C4-typePROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-100
Gene namesi
Name:nhr-100
ORF Names:C28D4.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC28D4.1; CE28893; WBGene00003690; nhr-100.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002235851 – 437Nuclear hormone receptor family member nhr-100Add BLAST437

Proteomic databases

PaxDbiO17611.
PeptideAtlasiO17611.

PTM databases

iPTMnetiO17611.

Expressioni

Gene expression databases

BgeeiWBGene00003690.

Interactioni

Protein-protein interaction databases

IntActiO17611. 1 interactor.
STRINGi6239.C28D4.1.1.

Structurei

3D structure databases

ProteinModelPortaliO17611.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated
Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri24 – 44NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri60 – 79NR C4-typePROSITE-ProRule annotationAdd BLAST20

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00850000132285.
HOGENOMiHOG000020487.
InParanoidiO17611.
OMAiTESFMAD.
OrthoDBiEOG091G0AVF.
PhylomeDBiO17611.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O17611-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIPFNSVSK IQWRNPSPVS DTSCLVCGDP HGKRHYGAMS CNGCKGFFRR
60 70 80 90 100
SIWEKRTYKC SFNNECIIEF KYRNRCRACR LKRCLHVGMD ANAVRSERTR
110 120 130 140 150
KIKTEIDGDV KLEIKEEPAD SEDADDECPL DIKPDIAMAW QTKEIIAHML
160 170 180 190 200
YEEDRVLNWE EPYNKLRYYT MDSEVLQAIK DPSQVCARTK INWNSHSRPL
210 220 230 240 250
ITIEALRFNW CRTFTLTIDW FETLPEYRAL IDDDKELLVK FSLMPVGWLW
260 270 280 290 300
YAYKSYEYRC DGIVFVDGSW FPRDKTIQQQ VCPTCVLYYG RITESFMADV
310 320 330 340 350
VNSMKELEMD ETEMVLLKAI CHLQPDYRLT RRGNDVISTG REKYKRALCE
360 370 380 390 400
YIRMKSNGFM DASFRLCKLM QILPVVDILG KYEDESALLV SLGETEFNGS
410 420 430
GGGLPYDIHA SDSHFARKNR RKSDNQYHQQ HVPLHIQ
Length:437
Mass (Da):51,142
Last modified:December 1, 2001 - v3
Checksum:iCF5B539264B0096A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY305849 mRNA. Translation: AAR11993.1.
Z82259 Genomic DNA. Translation: CAB05126.3.
PIRiT19540.
RefSeqiNP_501731.1. NM_069330.5.
UniGeneiCel.7765.

Genome annotation databases

EnsemblMetazoaiC28D4.1; C28D4.1; WBGene00003690.
GeneIDi177806.
KEGGicel:CELE_C28D4.1.
UCSCiC28D4.1.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY305849 mRNA. Translation: AAR11993.1.
Z82259 Genomic DNA. Translation: CAB05126.3.
PIRiT19540.
RefSeqiNP_501731.1. NM_069330.5.
UniGeneiCel.7765.

3D structure databases

ProteinModelPortaliO17611.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO17611. 1 interactor.
STRINGi6239.C28D4.1.1.

PTM databases

iPTMnetiO17611.

Proteomic databases

PaxDbiO17611.
PeptideAtlasiO17611.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC28D4.1; C28D4.1; WBGene00003690.
GeneIDi177806.
KEGGicel:CELE_C28D4.1.
UCSCiC28D4.1.1. c. elegans.

Organism-specific databases

CTDi177806.
WormBaseiC28D4.1; CE28893; WBGene00003690; nhr-100.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00850000132285.
HOGENOMiHOG000020487.
InParanoidiO17611.
OMAiTESFMAD.
OrthoDBiEOG091G0AVF.
PhylomeDBiO17611.

Miscellaneous databases

PROiO17611.

Gene expression databases

BgeeiWBGene00003690.

Family and domain databases

Gene3Di1.10.565.10. 2 hits.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNH100_CAEEL
AccessioniPrimary (citable) accession number: O17611
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: December 1, 2001
Last modified: November 2, 2016
This is version 119 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.