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Protein

Nuclear hormone receptor family member nhr-100

Gene

nhr-100

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Orphan nuclear receptor.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi21 – 96Nuclear receptorPROSITE-ProRule annotationAdd BLAST76
Zinc fingeri24 – 44NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri60 – 79NR C4-typePROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Receptor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear hormone receptor family member nhr-100
Gene namesi
Name:nhr-100
ORF Names:C28D4.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC28D4.1; CE28893; WBGene00003690; nhr-100.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002235851 – 437Nuclear hormone receptor family member nhr-100Add BLAST437

Proteomic databases

PaxDbiO17611.
PeptideAtlasiO17611.

PTM databases

iPTMnetiO17611.

Expressioni

Gene expression databases

BgeeiWBGene00003690.

Interactioni

Protein-protein interaction databases

IntActiO17611. 1 interactor.
STRINGi6239.C28D4.1.1.

Structurei

3D structure databases

ProteinModelPortaliO17611.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri24 – 44NR C4-typePROSITE-ProRule annotationAdd BLAST21
Zinc fingeri60 – 79NR C4-typePROSITE-ProRule annotationAdd BLAST20

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00870000136388.
HOGENOMiHOG000020487.
InParanoidiO17611.
OMAiTESFMAD.
OrthoDBiEOG091G0AVF.
PhylomeDBiO17611.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O17611-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIPFNSVSK IQWRNPSPVS DTSCLVCGDP HGKRHYGAMS CNGCKGFFRR
60 70 80 90 100
SIWEKRTYKC SFNNECIIEF KYRNRCRACR LKRCLHVGMD ANAVRSERTR
110 120 130 140 150
KIKTEIDGDV KLEIKEEPAD SEDADDECPL DIKPDIAMAW QTKEIIAHML
160 170 180 190 200
YEEDRVLNWE EPYNKLRYYT MDSEVLQAIK DPSQVCARTK INWNSHSRPL
210 220 230 240 250
ITIEALRFNW CRTFTLTIDW FETLPEYRAL IDDDKELLVK FSLMPVGWLW
260 270 280 290 300
YAYKSYEYRC DGIVFVDGSW FPRDKTIQQQ VCPTCVLYYG RITESFMADV
310 320 330 340 350
VNSMKELEMD ETEMVLLKAI CHLQPDYRLT RRGNDVISTG REKYKRALCE
360 370 380 390 400
YIRMKSNGFM DASFRLCKLM QILPVVDILG KYEDESALLV SLGETEFNGS
410 420 430
GGGLPYDIHA SDSHFARKNR RKSDNQYHQQ HVPLHIQ
Length:437
Mass (Da):51,142
Last modified:December 1, 2001 - v3
Checksum:iCF5B539264B0096A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY305849 mRNA. Translation: AAR11993.1.
Z82259 Genomic DNA. Translation: CAB05126.3.
PIRiT19540.
RefSeqiNP_501731.1. NM_069330.5.
UniGeneiCel.7765.

Genome annotation databases

EnsemblMetazoaiC28D4.1; C28D4.1; WBGene00003690.
GeneIDi177806.
KEGGicel:CELE_C28D4.1.
UCSCiC28D4.1.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiNH100_CAEEL
AccessioniPrimary (citable) accession number: O17611
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: December 1, 2001
Last modified: August 30, 2017
This is version 125 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families