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Protein
Submitted name:

Uncharacterized protein

Gene

eat-16

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activator activity Source: WormBase
  • signal transducer activity Source: InterPro

GO - Biological processi

  • dopamine receptor signaling pathway Source: WormBase
  • intracellular signal transduction Source: InterPro
  • modulation of chemical synaptic transmission Source: WormBase
  • negative regulation of locomotion Source: WormBase
  • nematode larval development Source: WormBase
  • phospholipase C-inhibiting G-protein coupled receptor signaling pathway Source: WormBase
  • regulation of G-protein coupled receptor protein signaling pathway Source: WormBase
  • regulation of GTPase activity Source: WormBase
  • regulation of locomotion Source: WormBase
  • regulation of oviposition Source: WormBase
  • regulation of pharyngeal pumping Source: WormBase
  • reproduction Source: WormBase
  • response to food Source: WormBase

Enzyme and pathway databases

ReactomeiR-CEL-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:eat-16Imported
ORF Names:C16C2.2Imported, CELE_C16C2.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC16C2.2a ; CE17404 ; WBGene00001145 ; eat-16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiO17589
PaxDbiO17589
PeptideAtlasiO17589

Expressioni

Gene expression databases

BgeeiWBGene00001145
ExpressionAtlasiO17589 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi6239.C16C2.2a.2

Structurei

3D structure databases

ProteinModelPortaliO17589
SMRiO17589
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 90DEPInterPro annotationAdd BLAST76
Domaini287 – 407RGSInterPro annotationAdd BLAST121

Phylogenomic databases

eggNOGiKOG3589 Eukaryota
ENOG410YMJD LUCA
GeneTreeiENSGT00760000119142
HOGENOMiHOG000220864
InParanoidiO17589
KOiK16449
OMAiELLGHMW
OrthoDBiEOG091G05MO
PhylomeDBiO17589

Family and domain databases

CDDicd00068 GGL, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000591 DEP_dom
IPR015898 G-protein_gamma-like_dom
IPR036284 GGL_sf
IPR016137 RGS
IPR036305 RGS_sf
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00610 DEP, 1 hit
PF00631 G-gamma, 1 hit
PF00615 RGS, 1 hit
PRINTSiPR01301 RGSPROTEIN
SMARTiView protein in SMART
SM00049 DEP, 1 hit
SM00224 GGL, 1 hit
SM00315 RGS, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF48097 SSF48097, 1 hit
SSF48670 SSF48670, 1 hit
PROSITEiView protein in PROSITE
PS50186 DEP, 1 hit
PS50132 RGS, 1 hit

Sequencei

Sequence statusi: Complete.

O17589-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMPPLTKIEV LAKRVMEGAQ LKTHKYFRIA VPHAITGQQL IALVLERGAP
60 70 80 90 100
DDEAEASHLA SLLLHHGYMF PVIEHGQPFK DDGTLYRLQR PYFWPSQAEL
110 120 130 140 150
VPDVEYAIYL NKRLLRNEQK HGLEEDEVES FNRLADVLAH MWAFIVQQSE
160 170 180 190 200
LQLKQQKEKK KVDKVVFDSE ERAFWKIRKP SRGGPNFLED PYMKIEKKIR
210 220 230 240 250
RQNAQGYRCL MDRLRFAIKT KPWLKALKAS DTMVTWVDQR AEFDPFLHPP
260 270 280 290 300
QPSNPWISDE ASFWNQPTDT SSAEIPTEKR VKRWGLSVQE LVKDPIGRQV
310 320 330 340 350
LETFLESEFS SENIRFWIAI QDLKYAPNEQ IYQKAERIRE EFLAQGAPAQ
360 370 380 390 400
VNVDNRTLDQ TLECISKAKD ASQMRFAFYH SEEHVFTLMA KDSYPRFVRS
410 420 430 440 450
QIYKAVLTAA QQHGTKRLGW RNFVFNMGTT KKPATSKPAK PQDSIGTGQV
460 470
LPKQLSSDSL PVRQAHGVKP DPE
Length:473
Mass (Da):54,686
Last modified:August 1, 1998 - v2
Checksum:i27B0CD420A8B34D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA Translation: CAB02742.1
PIRiT19337
RefSeqiNP_740904.1, NM_170911.4
UniGeneiCel.20772

Genome annotation databases

EnsemblMetazoaiC16C2.2a.1; C16C2.2a.1; WBGene00001145
C16C2.2a.2; C16C2.2a.2; WBGene00001145
GeneIDi172823
KEGGicel:CELE_C16C2.2
UCSCiC16C2.2a.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiO17589_CAEEL
AccessioniPrimary (citable) accession number: O17589
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: August 1, 1998
Last modified: May 23, 2018
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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