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O17450

- PE48_CHRBE

UniProt

O17450 - PE48_CHRBE

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Protein
Peritrophin-48
Gene
N/A
Organism
Chrysomya bezziana (Old world screw-worm fly)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Binds chitin and may bind related oligosaccharide structures.

GO - Molecular functioni

  1. chitin binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. chitin metabolic process Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Chitin-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Peritrophin-48
OrganismiChrysomya bezziana (Old world screw-worm fly)
Taxonomic identifieri69364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaOestroideaCalliphoridaeChrysomyinaeChrysomya

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020
Add
BLAST
Chaini21 – 379359Peritrophin-48
PRO_0000023614Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi60 ↔ 73 By similarity
Disulfide bondi120 ↔ 133 By similarity
Glycosylationi150 – 1501N-linked (GlcNAc...) Reviewed prediction
Glycosylationi168 – 1681N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi185 ↔ 198 By similarity
Glycosylationi247 – 2471N-linked (GlcNAc...) Reviewed prediction
Glycosylationi252 – 2521N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi324 ↔ 337 By similarity
Glycosylationi341 – 3411N-linked (GlcNAc...) Reviewed prediction
Glycosylationi356 – 3561N-linked (GlcNAc...) Reviewed prediction
Glycosylationi373 – 3731N-linked (GlcNAc...) Reviewed prediction

Post-translational modificationi

Glycosylated.

Keywords - PTMi

Disulfide bond, Glycoprotein

Expressioni

Tissue specificityi

Larval peritrophic membrane.

Structurei

3D structure databases

ProteinModelPortaliO17450.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 8359Chitin-binding type-2 1
Add
BLAST
Domaini86 – 14358Chitin-binding type-2 2
Add
BLAST
Domaini151 – 20858Chitin-binding type-2 3
Add
BLAST
Domaini224 – 28360Chitin-binding type-2 4
Add
BLAST
Domaini285 – 35672Chitin-binding type-2 5
Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Family and domain databases

Gene3Di2.170.140.10. 3 hits.
InterProiIPR002557. Chitin-bd_dom.
[Graphical view]
PfamiPF01607. CBM_14. 4 hits.
[Graphical view]
SMARTiSM00494. ChtBD2. 5 hits.
[Graphical view]
SUPFAMiSSF57625. SSF57625. 4 hits.
PROSITEiPS50940. CHIT_BIND_II. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O17450-1 [UniParc]FASTAAdd to Basket

« Hide

MKAKTLTATL ALILLAFAQA DYDVASYCQL VQSGTKLPSL DSCQNYYTCV    50
SNGLPTLSSC SSGYVFNKDS QQCVPTGSFN CFFGVANPCQ NQDKKFVPSA 100
KQCNEWHYCL AGAIAGTGTC KEGQIFNFAK QSCVYGECSN TGNNILDSPN 150
LSVCQIMPNG IYFGDNKNCS TWHKCSGMEE KKGTCPNGDN FDPTYASCVP 200
SNMPACSRIQ NPPSTGVVSG PPSTSPCSLG TVVGDLTSCS VYYKCENATR 250
SNSTIWNTYT CSGQFFDVIS KQCTSTNQAR TLKGCNRCQF TTGSMYWVNA 300
VDPQCSEYFT CSNGLETKST ASTCGAGNFF NEDLQYCMIG NSTVGQYAQT 350
HGACENYTCN PNTRLCNLVT ATNTTSSHR 379
Length:379
Mass (Da):40,829
Last modified:January 1, 1998 - v1
Checksum:iFCDCC6AAE7976479
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti159 – 1591N → H in AAD25103. 1 Publication
Sequence conflicti167 – 1671K → T in AAD25103. 1 Publication
Sequence conflicti236 – 2361L → I in AAD25103. 1 Publication
Sequence conflicti263 – 2631G → S in AAD25103. 1 Publication
Sequence conflicti278 – 2781Q → P in AAD25103. 1 Publication
Sequence conflicti282 – 2821L → F in AAD25103. 1 Publication
Sequence conflicti286 – 2861N → I in AAD25103. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF030557 mRNA. Translation: AAB86623.1.
AF139718 Genomic DNA. Translation: AAD25103.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF030557 mRNA. Translation: AAB86623.1 .
AF139718 Genomic DNA. Translation: AAD25103.1 .

3D structure databases

ProteinModelPortali O17450.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.170.140.10. 3 hits.
InterProi IPR002557. Chitin-bd_dom.
[Graphical view ]
Pfami PF01607. CBM_14. 4 hits.
[Graphical view ]
SMARTi SM00494. ChtBD2. 5 hits.
[Graphical view ]
SUPFAMi SSF57625. SSF57625. 4 hits.
PROSITEi PS50940. CHIT_BIND_II. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification and molecular characterisation of a peritrophin gene, peritrophin-48, from the myiasis fly Chrysomya bezziana."
    Vuocolo T., Eisemann C.H., Pearson R.D., Willadsen P., Tellam R.L.
    Insect Biochem. Mol. Biol. 31:919-932(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
    Tissue: Larval peritrophic membrane.

Entry informationi

Entry nameiPE48_CHRBE
AccessioniPrimary (citable) accession number: O17450
Secondary accession number(s): Q9XZF7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: January 1, 1998
Last modified: October 16, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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