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O17450 (PE48_CHRBE) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Binds chitin and may bind related oligosaccharide structures.

Tissue specificity

Larval peritrophic membrane.

Post-translational modification

Glycosylated.

Sequence similarities

Contains 5 chitin-binding type-2 domains.

Ontologies

Keywords
   DomainRepeat
Signal
   LigandChitin-binding
   PTMDisulfide bond
Glycoprotein
Gene Ontology (GO)
   Biological_processchitin metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: InterPro

   Molecular_functionchitin binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020
Chain21 – 379359Peritrophin-48
PRO_0000023614

Regions

Domain25 – 8359Chitin-binding type-2 1
Domain86 – 14358Chitin-binding type-2 2
Domain151 – 20858Chitin-binding type-2 3
Domain224 – 28360Chitin-binding type-2 4
Domain285 – 35672Chitin-binding type-2 5

Amino acid modifications

Glycosylation1501N-linked (GlcNAc...) Potential
Glycosylation1681N-linked (GlcNAc...) Potential
Glycosylation2471N-linked (GlcNAc...) Potential
Glycosylation2521N-linked (GlcNAc...) Potential
Glycosylation3411N-linked (GlcNAc...) Potential
Glycosylation3561N-linked (GlcNAc...) Potential
Glycosylation3731N-linked (GlcNAc...) Potential
Disulfide bond60 ↔ 73 By similarity
Disulfide bond120 ↔ 133 By similarity
Disulfide bond185 ↔ 198 By similarity
Disulfide bond324 ↔ 337 By similarity

Experimental info

Sequence conflict1591N → H in AAD25103. Ref.1
Sequence conflict1671K → T in AAD25103. Ref.1
Sequence conflict2361L → I in AAD25103. Ref.1
Sequence conflict2631G → S in AAD25103. Ref.1
Sequence conflict2781Q → P in AAD25103. Ref.1
Sequence conflict2821L → F in AAD25103. Ref.1
Sequence conflict2861N → I in AAD25103. Ref.1

Sequences

Sequence LengthMass (Da)Tools
O17450 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: FCDCC6AAE7976479

FASTA37940,829
        10         20         30         40         50         60 
MKAKTLTATL ALILLAFAQA DYDVASYCQL VQSGTKLPSL DSCQNYYTCV SNGLPTLSSC 

        70         80         90        100        110        120 
SSGYVFNKDS QQCVPTGSFN CFFGVANPCQ NQDKKFVPSA KQCNEWHYCL AGAIAGTGTC 

       130        140        150        160        170        180 
KEGQIFNFAK QSCVYGECSN TGNNILDSPN LSVCQIMPNG IYFGDNKNCS TWHKCSGMEE 

       190        200        210        220        230        240 
KKGTCPNGDN FDPTYASCVP SNMPACSRIQ NPPSTGVVSG PPSTSPCSLG TVVGDLTSCS 

       250        260        270        280        290        300 
VYYKCENATR SNSTIWNTYT CSGQFFDVIS KQCTSTNQAR TLKGCNRCQF TTGSMYWVNA 

       310        320        330        340        350        360 
VDPQCSEYFT CSNGLETKST ASTCGAGNFF NEDLQYCMIG NSTVGQYAQT HGACENYTCN 

       370 
PNTRLCNLVT ATNTTSSHR 

« Hide

References

[1]"Identification and molecular characterisation of a peritrophin gene, peritrophin-48, from the myiasis fly Chrysomya bezziana."
Vuocolo T., Eisemann C.H., Pearson R.D., Willadsen P., Tellam R.L.
Insect Biochem. Mol. Biol. 31:919-932(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
Tissue: Larval peritrophic membrane.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF030557 mRNA. Translation: AAB86623.1.
AF139718 Genomic DNA. Translation: AAD25103.1.

3D structure databases

ProteinModelPortalO17450.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.170.140.10. 3 hits.
InterProIPR002557. Chitin-bd_dom.
[Graphical view]
PfamPF01607. CBM_14. 4 hits.
[Graphical view]
SMARTSM00494. ChtBD2. 5 hits.
[Graphical view]
SUPFAMSSF57625. SSF57625. 4 hits.
PROSITEPS50940. CHIT_BIND_II. 5 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePE48_CHRBE
AccessionPrimary (citable) accession number: O17450
Secondary accession number(s): Q9XZF7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: January 1, 1998
Last modified: October 16, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families